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Details
Link-It Detail - Disease - Parkinsonian Disorders
Debug Stats
  • ### Total Build Time: 79 ms 40.627 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 609 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.403 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 2.809 KB
  • CONCEPT_RELATIONSHIPS gt=30 ms Completed: 30 ms rowSize= 13.649 KB
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 19.499 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Parkinsonian Disorders C0242422
Definition (1)
A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Basal Ganglia Diseases C0004782
img Movement Disorders C0026650
Children (3)
img Parkinson Disease C0030567
img Parkinson Disease, Secondary C0030569
img Lewy Body Disease C0752347
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Basal Ganglia Diseases C0004782
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076824img Movement Disorders C0026650
Relationships (129)

Relation Types:
diso_​to_​anat : 24
diso_​to_​chem : 54
diso_​to_​diso : 40
diso_​to_​phen : 2
diso_​to_​phys : 9


Relationships:
none : 116
entry_​version_​of : 1
isa : 5
mapped_​to : 3
may_​treat : 4
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN327img genetic aspects C0017399
DISO_to_DISO323img chemically induced C0007994
DISO_to_DISO319img chemically induced C0007994
DISO_to_PHEN251img genetic aspects C0017399
DISO_to_DISO198img Complication Aspects C1171258
DISO_to_ANAT145img Neurons C0027882
DISO_to_ANAT136img Substantia Nigra C0038590
DISO_to_ANAT132img Neurons C0027882
DISO_to_DISO128img Complication Aspects C1171258
DISO_to_CHEM126img Dopamine C0013030
DISO_to_ANAT125img Substantia Nigra C0038590
DISO_to_ANAT118img Brain C0006104
DISO_to_ANAT114img Corpus Striatum C0010097
DISO_to_CHEM108img Dopamine C0013030
DISO_to_CHEM104img (-)-3-(3,4-Dihydroxyphenyl)-L-alanine C0023570
DISO_to_ANAT101img Corpus Striatum C0010097
DISO_to_ANAT97img Brain C0006104
DISO_to_CHEM93img Antiparkinson Agents C0003405
DISO_to_CHEM77img (-)-3-(3,4-Dihydroxyphenyl)-L-alanine C0023570
DISO_to_CHEM75img Agents, Neuroprotective C0242912
DISO_to_CHEM75img Antiparkinson Agents C0003405
DISO_to_DISO73img Parkinson Disease C0030567
DISO_to_PHYS66img Mutation C0026882
DISO_to_DISO62img Dyskinesia, Drug-Induced C0013386
DISO_to_DISO61img Dementia C0497327
Genes (535)

Species:
human : 535
Page Size
Current 25
  Page 1 of 22
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanAD10780912Alzheimer disease-10
img OMIM, Score=1000, UMLKSK CUI: C0242422
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanLOC729225729225
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanPARK12677662Parkinson disease 12 (susceptibility)
img OMIM, Score=1000, UMLKSK CUI: C0242422
HumanC1orf190541468
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanAD9450086Alzheimer disease 9
img OMIM, Score=1000, UMLKSK CUI: C0242422
HumanMIR133B442890microRNA 133b
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanCDNF441549cerebral dopamine neurotrophic factor
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanZYG11A440590zyg-11 family member A, cell cycle regulator
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanHSP90AB2P391634heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanSKINTL391037Skint-like, pseudogene
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanLDLRAD1388633low density lipoprotein receptor class A domain containing 1
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanLOC388630388630
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanC1orf175374977
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanNDUFS7374291NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanAD8353128Alzheimer disease 8
img OMIM, Score=1000, UMLKSK CUI: C0242422
HumanFAM159A348378family with sequence similarity 159, member A
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanKIAA1267284058
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanCYP4X1260293cytochrome P450, family 4, subfamily X, polypeptide 1
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanNEGR1257194neuronal growth regulator 1
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanPCSK9255738proprotein convertase subtilisin/kexin type 9
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanSTH246744saitohin
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanMTIF3219402mitochondrial translational initiation factor 3
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanSLFNL1200172schlafen-like 1
INFERRED, Score=800, UMLKSK CUI: C0242422
HumanSLC5A9200010solute carrier family 5 (sodium/sugar cotransporter), member 9
INFERRED, Score=800, UMLKSK CUI: C0242422
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0242422Parkinsonian Disorders0self