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Details
Link-It Detail - Disease - Papillary thyroid carcinoma
Debug Stats
  • ### Total Build Time: 34 ms 39.121 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 999 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=30 ms Completed: 30 ms rowSize= 36.467 KB
  • CONCEPT_XREFS gt=2 ms Completed: 1 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Papillary thyroid carcinoma C0238463
Definition (1)
A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. It is linked to radiation exposure and is the most common malignant thyroid lesion, comprising 75% to 80% of all thyroid cancers in iodine sufficient countries. Diagnostic procedures include: thyroid function tests, thyroid radioisotope scanning, thyroid ultrasound, and fine needle biopsy. Microscopically, the diagnosis is based on the distinct characteristics of the malignant cells, which include enlargement, oval shape, elongation, and overlapping of the nuclei. The nuclei also display clearing or have a ground glass appearance. Depending on the size and spread of the disease, surgical options include lobectomy, and partial or complete thyroidectomy. Adjuvant treatment options include: radioiodine therapy, TSH suppression and external radiation.
Genes (140)

Species:
human : 139
mouse : 1
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseNCOA48031nuclear receptor coactivator 4
img NCI, Score=801, Pubmed Id: 11861385, UMLKSK CUI: C0238463
HumanMIR146A406938microRNA 146a
img GENERIF, Score=1000, Pubmed Id: 18474871, UMLKSK CUI: C0238463
HumanNEWENTRY192343Record to support submission of GeneRIFs for a gene not in Gene (human; man).
img GENERIF, Score=717, Pubmed Id: 18505566, UMLKSK CUI: C0238463
HumanSLC5A8160728solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
img NCI, Score=801, Pubmed Id: 15687339, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 15687339, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 15687339, UMLKSK CUI: C0238463
HumanGADD45GIP190480growth arrest and DNA-damage-inducible, gamma interacting protein 1
img NCI, Score=801, Pubmed Id: 12716909, UMLKSK CUI: C0238463
HumanKISS1R84634KISS1 receptor
img NCI, Score=801, Pubmed Id: 11994395, UMLKSK CUI: C0238463
HumanNAA1580155N(alpha)-acetyltransferase 15, NatA auxiliary subunit
img GENERIF, Score=988, Pubmed Id: 12140756, UMLKSK CUI: C0238463
img GENERIF, Score=756, Pubmed Id: 16279846, UMLKSK CUI: C0238463
HumanC11orf3056946chromosome 11 open reading frame 30
img GENERIF, Score=1000, Pubmed Id: 18787380, UMLKSK CUI: C0238463
HumanERRFI154206ERBB receptor feedback inhibitor 1
img GENERIF, Score=1000, Pubmed Id: 19040996, UMLKSK CUI: C0238463
HumanWWOX51741WW domain containing oxidoreductase
img GENERIF, Score=988, Pubmed Id: 18047428, UMLKSK CUI: C0238463
HumanTCO50975Thyroid carcinoma, nonmedullary, with cell oxyphilia
img NCI, Score=801, Pubmed Id: 10427154, UMLKSK CUI: C0238463
HumanERC123085ELKS/RAB6-interacting/CAST family member 1
img GENERIF, Score=1000, Pubmed Id: 12203787, UMLKSK CUI: C0238463
HumanPRSS2311098protease, serine, 23
img NCI, Score=801, Pubmed Id: 15735049, UMLKSK CUI: C0238463
HumanFRS210818fibroblast growth factor receptor substrate 2
img NCI, Score=801, Pubmed Id: 11390647, UMLKSK CUI: C0238463
HumanTFG10342TRK-fused gene
img NCI, Score=801, Pubmed Id: 10861999, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 9169129, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 10092511, UMLKSK CUI: C0238463
HumanTOB110140transducer of ERBB2, 1
img NCI, Score=801, Pubmed Id: 15766599, UMLKSK CUI: C0238463
HumanCXCL149547chemokine (C-X-C motif) ligand 14
img GENERIF, Score=756, Pubmed Id: 18676742, UMLKSK CUI: C0238463
HumanDHRS39249dehydrogenase/reductase (SDR family) member 3
img GENERIF, Score=756, Pubmed Id: 18676742, UMLKSK CUI: C0238463
HumanTRIM248805tripartite motif containing 24
img NCI, Score=801, Pubmed Id: 10439047, UMLKSK CUI: C0238463
HumanTP638626tumor protein p63
img NCI, Score=801, Pubmed Id: 15116328, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 14506636, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 14506636, UMLKSK CUI: C0238463
img NCI, Score=801, Pubmed Id: 14506636, UMLKSK CUI: C0238463
HumanPARG8505poly (ADP-ribose) glycohydrolase
img NCI, Score=801, Pubmed Id: 10363163, UMLKSK CUI: C0238463
HumanCDC78317cell division cycle 7
img NCI, Score=801, Pubmed Id: 16676402, UMLKSK CUI: C0238463
HumanNAA108260N(alpha)-acetyltransferase 10, NatA catalytic subunit
img GENERIF, Score=756, Pubmed Id: 16279846, UMLKSK CUI: C0238463
HumanRASSF78045Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
img GENERIF, Score=756, Pubmed Id: 15098441, UMLKSK CUI: C0238463
HumanNCOA48031nuclear receptor coactivator 4
Click here to display 20 evidence detail records.
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0238463Papillary thyroid carcinoma0self