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Details
Link-It Detail - Disease - Anaplastic thyroid carcinoma
Debug Stats
  • ### Total Build Time: 58 ms 40.792 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 354 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 590 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=47 ms Completed: 47 ms rowSize= 38.534 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Anaplastic thyroid carcinoma C0238461
Definition (1)
A primary carcinoma of the thyroid gland composed of undifferentiated cells. The malignant cells demonstrate evidence of epithelial differentiation, either by immunohistochemistry or electron microscopic studies. Microscopically, in the majority of cases there is a mixture of spindle, epithelioid, and giant cells. The vast majority of the patients present with a rapidly enlarging neck mass. The clinical course is usually aggressive.
Genes (43)

Species:
human : 43
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanRXFP2122042relaxin/insulin-like family peptide receptor 2
img NCI, Score=801, Pubmed Id: 12684664, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 12684664, UMLKSK CUI: C0238461
HumanITCH83737itchy E3 ubiquitin protein ligase
img GENERIF, Score=756, Pubmed Id: 19016753, UMLKSK CUI: C0238461
HumanDUSP2678986dual specificity phosphatase 26 (putative)
img GENERIF, Score=1000, Pubmed Id: 16924234, UMLKSK CUI: C0238461
HumanUBE2C11065ubiquitin-conjugating enzyme E2C
img GENERIF, Score=1000, Pubmed Id: 18753363, UMLKSK CUI: C0238461
img GENERIF, Score=988, Pubmed Id: 16106252, UMLKSK CUI: C0238461
HumanKIAA01019768KIAA0101
img GENERIF, Score=1000, Pubmed Id: 15789362, UMLKSK CUI: C0238461
HumanABCG29429ATP-binding cassette, sub-family G (WHITE), member 2
img GENERIF, Score=1000, Pubmed Id: 17938326, UMLKSK CUI: C0238461
HumanAURKB9212aurora kinase B
img NCI, Score=801, Pubmed Id: 15562011, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 15562011, UMLKSK CUI: C0238461
img GENERIF, Score=756, Pubmed Id: 15562011, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 15699543, UMLKSK CUI: C0238461
HumanTP638626tumor protein p63
img NCI, Score=801, Pubmed Id: 12234063, UMLKSK CUI: C0238461
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img GENERIF, Score=756, Pubmed Id: 12519884, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 12519884, UMLKSK CUI: C0238461
img GENERIF, Score=923, Pubmed Id: 18089812, UMLKSK CUI: C0238461
HumanPAX87849paired box 8
img GENERIF, Score=756, Pubmed Id: 12970322, UMLKSK CUI: C0238461
HumanTPO7173thyroid peroxidase
img NCI, Score=801, Pubmed Id: 8157713, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 14976143, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 8631011, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 11383870, UMLKSK CUI: C0238461
HumanTP537157tumor protein p53
img GENERIF, Score=845, Pubmed Id: 16943578, UMLKSK CUI: C0238461
HumanNKX2-17080
img NCI, Score=801, Pubmed Id: 11325833, UMLKSK CUI: C0238461
img GENERIF, Score=756, Pubmed Id: 17671725, UMLKSK CUI: C0238461
img NCI, Score=801, Pubmed Id: 1726928, UMLKSK CUI: C0238461
HumanTGFB37043transforming growth factor, beta 3
img GENERIF, Score=884, Pubmed Id: 12432546, UMLKSK CUI: C0238461
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=884, Pubmed Id: 12432546, UMLKSK CUI: C0238461
HumanTG7038thyroglobulin
img GENERIF, Score=756, Pubmed Id: 17671725, UMLKSK CUI: C0238461
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=1000, Pubmed Id: 18201269, UMLKSK CUI: C0238461
img GENERIF, Score=717, Pubmed Id: 16288728, UMLKSK CUI: C0238461
HumanHNF1B6928HNF1 homeobox B
img GENERIF, Score=685, Pubmed Id: 18399756, UMLKSK CUI: C0238461
HumanHNF1A6927HNF1 homeobox A
img GENERIF, Score=685, Pubmed Id: 18399756, UMLKSK CUI: C0238461
HumanSLC5A56528solute carrier family 5 (sodium/iodide cotransporter), member 5
img GENERIF, Score=717, Pubmed Id: 16264365, UMLKSK CUI: C0238461
HumanRET5979ret proto-oncogene
img GENERIF, Score=861, Pubmed Id: 17270245, UMLKSK CUI: C0238461
HumanPTH1R5745parathyroid hormone 1 receptor
img GENERIF, Score=923, Pubmed Id: 16213899, UMLKSK CUI: C0238461
HumanPTEN5728phosphatase and tensin homolog
img GENERIF, Score=1000, Pubmed Id: 12203792, UMLKSK CUI: C0238461
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=756, Pubmed Id: 12970322, UMLKSK CUI: C0238461
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
img GENERIF, Score=1000, Pubmed Id: 16288007, UMLKSK CUI: C0238461
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0238461Anaplastic thyroid carcinoma0self