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Details
Link-It Detail - Disease - X-linked agammaglobulinemia
Debug Stats
  • ### Total Build Time: 11 ms 12.868 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 447 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 10.753 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
X-linked agammaglobulinemia C0221026
Definition (1)
X-linked agammaglobulinemia. An immunodeficiency state characterized (usually) by profoundly low concentrations of serum immunoglobulins of all classes, although occasionally significant amounts of one or more isotypes can be found. The fundamental defect in XLA affects early lineage B cells.
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanTLR851311toll-like receptor 8
img GENERIF, Score=756, Pubmed Id: 17090647, UMLKSK CUI: C0221026
HumanTNF7124tumor necrosis factor
img GENERIF, Score=756, Pubmed Id: 17090647, UMLKSK CUI: C0221026
HumanMAPK85599mitogen-activated protein kinase 8
img GENERIF, Score=1000, Pubmed Id: 12148599, UMLKSK CUI: C0221026
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=756, Pubmed Id: 17090647, UMLKSK CUI: C0221026
HumanBTK695Bruton agammaglobulinemia tyrosine kinase
img GENERIF, Score=1000, Pubmed Id: 16951917, UMLKSK CUI: C0221026
img GENERIF, Score=717, Pubmed Id: 11438999, UMLKSK CUI: C0221026
img GENERIF, Score=756, Pubmed Id: 17707910, UMLKSK CUI: C0221026
img GENERIF, Score=694, Pubmed Id: 18241233, UMLKSK CUI: C0221026
img GENERIF, Score=923, Pubmed Id: 11668622, UMLKSK CUI: C0221026
img GENERIF, Score=1000, Pubmed Id: 18726917, UMLKSK CUI: C0221026
img GENERIF, Score=717, Pubmed Id: 14974089, UMLKSK CUI: C0221026
img GENERIF, Score=1000, Pubmed Id: 12405164, UMLKSK CUI: C0221026
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0221026X-linked agammaglobulinemia0self