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Details
Link-It Detail - Disease - Esthesioneuroblastoma, Olfactory
Debug Stats
  • ### Total Build Time: 43 ms 34.618 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 415 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 582 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 991 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.045 KB
  • CONCEPT_RELATIONSHIPS gt=19 ms Completed: 19 ms rowSize= 14.964 KB
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 12.284 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Esthesioneuroblastoma, Olfactory C0206717
Olfactory Neuroblastoma
Definition (1)
A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Neuroblastoma C0027819
img Olfactory Nerve Diseases C0751937
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276529img Neuroblastoma C0027819
img Neoplasms C0027651img Neoplasms by Histologic Type C00276528img Neuroblastoma C0027819
img Nervous System Diseases C0027765img Cranial Nerve Diseases C00102664img Olfactory Nerve Diseases C0751937
Relationships (56)

Relation Types:
diso_​to_​anat : 25
diso_​to_​diso : 30
diso_​to_​phen : 1


Relationships:
none : 15
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 4
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 6
is_​normal_​tissue_​origin_​of_​disease : 5
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 4
may_​be_​cytogenetic_​abnormality_​of_​disease : 2
may_​be_​finding_​of_​disease : 6
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO115img NEOPL NOSE C0028433
DISO_to_ANAT98img Nasal Cavity C0027423
DISO_to_DISO90img NEOPL NOSE C0028433
DISO_to_ANAT76img Nasal Cavity C0027423
DISO_to_DISO10img Accessory Sinus Neoplasm C0030470
DISO_to_DISO9img Accessory Sinus Neoplasm C0030470
DISO_to_DISO9img Complication Aspects C1171258
DISO_to_DISO8img Complication Aspects C1171258
DISO_to_DISO6img LOCAL NEOPL RECURRENCE C0027643
DISO_to_DISO6img NEOPL SKULL BASE C0376527
DISO_to_DISO5img Brain Neoplasms C0006118
DISO_to_DISO5img COMPL POSTOP C0032787
DISO_to_DISO5img LOCAL NEOPL RECURRENCE C0027643
DISO_to_DISO5img Meningeal Neoplasms C0025284
DISO_to_PHEN5img genetic aspects C0017399
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell, Neuroepithelial C1449624
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Cranial Nerves C0010268
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Ectomesenchyme C1518271
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Embryonic Cell C1947950
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Embryonic tissue C0920502
DISO_to_ANATis_associated_anatomic_site_ofimg Head and neck structure C0460004
DISO_to_ANATis_associated_anatomic_site_ofimg Nasal Cavity and Paranasal Sinus C1882010
DISO_to_ANATis_associated_anatomic_site_ofimg Nasal sinus C0030471
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanSPA1753340sperm autoantigenic protein 17
img NCI, Score=801, Pubmed Id: 16311122, UMLKSK CUI: C0206717
HumanPSIP111168PC4 and SFRS1 interacting protein 1
img NCI, Score=801, Pubmed Id: 12175342, UMLKSK CUI: C0206717
HumanTOP2A7153topoisomerase (DNA) II alpha 170kDa
img GENERIF, Score=861, Pubmed Id: 17607373, UMLKSK CUI: C0206717
HumanSYP6855synaptophysin
img NCI, Score=801, Pubmed Id: 9548430, UMLKSK CUI: C0206717
HumanSAG6295S-antigen; retina and pineal gland (arrestin)
img NCI, Score=801, Pubmed Id: 2958128, UMLKSK CUI: C0206717
HumanCD994267CD99 molecule
img NCI, Score=801, Pubmed Id: 9580174, UMLKSK CUI: C0206717
HumanFLI12313Fli-1 proto-oncogene, ETS transcription factor
img NCI, Score=801, Pubmed Id: 9580174, UMLKSK CUI: C0206717
HumanASCL1429achaete-scute complex homolog 1 (Drosophila)
img NCI, Score=801, Pubmed Id: 15272537, UMLKSK CUI: C0206717
img NCI, Score=801, Pubmed Id: 15272537, UMLKSK CUI: C0206717
img GENERIF, Score=861, Pubmed Id: 15272537, UMLKSK CUI: C0206717
img NCI, Score=801, Pubmed Id: 15272537, UMLKSK CUI: C0206717
img NCI, Score=801, Pubmed Id: 15272537, UMLKSK CUI: C0206717
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206717Esthesioneuroblastoma, Olfactory0self