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Details
Link-It Detail - Disease - Adrenocortical Carcinoma
Debug Stats
  • ### Total Build Time: 214 ms 68.814 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 346 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 390 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 992 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 5.335 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 16.463 KB
  • CONCEPT_GENES gt=213 ms Completed: 213 ms rowSize= 43.953 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.158 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adrenocortical Carcinoma C0206686
Definition (1)
A rare cancer that forms in the outer layer of tissue of the adrenal gland (a small organ on top of each kidney that makes steroid hormones, adrenaline, and noradrenaline to control heart rate, blood pressure, and other body functions).
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Adrenal Cortex Neoplasms C0001618
img Adenocarcinoma C0001418
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Site C00276536img Adrenal Cortex Neoplasms C0001618
img Endocrine System Diseases C0014130img Endocrine Gland Neoplasms C00141325img Adrenal Cortex Neoplasms C0001618
img Endocrine System Diseases C0014130img Adrenal Gland Diseases C00016215img Adrenal Cortex Neoplasms C0001618
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Adenocarcinoma C0001418
Relationships (82)

Relation Types:
diso_​to_​anat : 27
diso_​to_​chem : 8
diso_​to_​diso : 36
diso_​to_​gene : 7
diso_​to_​phen : 3
diso_​to_​phys : 1


Relationships:
none : 29
clinically_​similar : 2
gene_​associated_​with_​disease : 7
gene_​product_​malfunction_​associated_​with_​disease : 3
is_​abnormal_​cell_​of_​disease : 9
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​finding_​of_​disease : 1
is_​not_​normal_​tissue_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 7
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​finding_​of_​disease : 5
permuted_​term_​of : 1
Page Size
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Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO253img Adrenal Cortex Neoplasms C0001618
DISO_to_DISO137img Adrenal Cortex Neoplasms C0001618
DISO_to_PHEN74img genetic aspects C0017399
DISO_to_CHEM31img Mitotane C0026256
DISO_to_DISO31img Adrenal Cortical Adenoma C0206667
DISO_to_DISO30img Complication Aspects C1171258
DISO_to_DISO26img Adrenal Gland Neoplasms C0001624
DISO_to_DISO25img Adrenal Cortical Adenoma C0206667
DISO_to_CHEM24img ANTINEOPL AGENTS HORMONAL C0282559
DISO_to_DISO22img Complication Aspects C1171258
DISO_to_DISO21img Adrenal Gland Neoplasms C0001624
DISO_to_PHEN19img genetic aspects C0017399
DISO_to_CHEM16img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO16img Pheochromocytoma C0031511
DISO_to_DISO12img LOCAL NEOPL RECURRENCE C0027643
DISO_to_DISO10img LOCAL NEOPL RECURRENCE C0027643
DISO_to_DISO10img Liver Neoplasms C0023903
DISO_to_ANAT9img In Blood C0005768
DISO_to_DISO9img Cushing Syndrome C0010481
DISO_to_DISO9img Lung Neoplasms C0024121
DISO_to_ANAT8img Inferior vena cava structure C0042458
DISO_to_DISO8img Lung Neoplasms C0024121
DISO_to_DISO8img Pheochromocytoma C0031511
DISO_to_PHEN8img Process of secretion C0036536
DISO_to_PHYS8img Germ-Line Mutation C0206530
Genes (32)

Species:
human : 32
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanDCUN1D154165DCN1, defective in cullin neddylation 1, domain containing 1
img NCI, Score=801, Pubmed Id: 15657565, UMLKSK CUI: C0206686
HumanMSLN10232mesothelin
img NCI, Score=801, Pubmed Id: 14576474, UMLKSK CUI: C0206686
HumanWT27491Wilms tumor 2
img OMIM, Score=1000, UMLKSK CUI: C0206686
HumanUROD7389uroporphyrinogen decarboxylase
img NCI, Score=801, Pubmed Id: 2102982, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 2102982, UMLKSK CUI: C0206686
HumanTP537157tumor protein p53
img GENERIF, Score=901, Pubmed Id: 16033918, UMLKSK CUI: C0206686
img OMIM, Score=1000, UMLKSK CUI: C0206686
img GENERIF, Score=1000, Pubmed Id: 11753428, UMLKSK CUI: C0206686
img GENERIF, Score=1000, Pubmed Id: 18989156, UMLKSK CUI: C0206686
img OMIM, Score=1000, UMLKSK CUI: C0206686
HumanNKX2-17080
img NCI, Score=801, Pubmed Id: 12472285, UMLKSK CUI: C0206686
HumanTGFBR27048transforming growth factor, beta receptor II (70/80kDa)
img GENERIF, Score=901, Pubmed Id: 16673206, UMLKSK CUI: C0206686
HumanNR2F27026nuclear receptor subfamily 2, group F, member 2
img NCI, Score=801, Pubmed Id: 10946877, UMLKSK CUI: C0206686
HumanSYP6855synaptophysin
img NCI, Score=801, Pubmed Id: 7723281, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 7723281, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 7828138, UMLKSK CUI: C0206686
HumanSCP26342sterol carrier protein 2
img NCI, Score=801, Pubmed Id: 8640304, UMLKSK CUI: C0206686
HumanPLCB35331phospholipase C, beta 3 (phosphatidylinositol-specific)
img NCI, Score=801, Pubmed Id: 12894496, UMLKSK CUI: C0206686
HumanMUC5AC4586mucin 5AC, oligomeric mucus/gel-forming
img NCI, Score=801, Pubmed Id: 15272531, UMLKSK CUI: C0206686
HumanIRS13667insulin receptor substrate 1
img NCI, Score=801, Pubmed Id: 12414625, UMLKSK CUI: C0206686
HumanINHA3623inhibin, alpha
img NCI, Score=801, Pubmed Id: 9647588, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 10810286, UMLKSK CUI: C0206686
HumanIGFBP23485insulin-like growth factor binding protein 2, 36kDa
img NCI, Score=801, Pubmed Id: 9851669, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 15241731, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 10965887, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 11174834, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 10965887, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 11174834, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 10706089, UMLKSK CUI: C0206686
HumanIGF2R3482insulin-like growth factor 2 receptor
img GENERIF, Score=901, Pubmed Id: 18611974, UMLKSK CUI: C0206686
HumanGATA62627GATA binding protein 6
img NCI, Score=801, Pubmed Id: 15666845, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 14666170, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 15767045, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 15767045, UMLKSK CUI: C0206686
HumanGATA42626GATA binding protein 4
img NCI, Score=801, Pubmed Id: 14666170, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 10449810, UMLKSK CUI: C0206686
HumanNR5A12516nuclear receptor subfamily 5, group A, member 1
img GENERIF, Score=861, Pubmed Id: 18824868, UMLKSK CUI: C0206686
HumanFGF42249fibroblast growth factor 4
img NCI, Score=801, Pubmed Id: 7923139, UMLKSK CUI: C0206686
HumanFGF12246fibroblast growth factor 1 (acidic)
img NCI, Score=801, Pubmed Id: 2777898, UMLKSK CUI: C0206686
img NCI, Score=801, Pubmed Id: 1964794, UMLKSK CUI: C0206686
HumanESR22100estrogen receptor 2 (ER beta)
img GENERIF, Score=1000, Pubmed Id: 18157729, UMLKSK CUI: C0206686
HumanCYP21A21589cytochrome P450, family 21, subfamily A, polypeptide 2
img NCI, Score=801, Pubmed Id: 11869873, UMLKSK CUI: C0206686
HumanCYP11B21585cytochrome P450, family 11, subfamily B, polypeptide 2
img NCI, Score=801, Pubmed Id: 9322959, UMLKSK CUI: C0206686
HumanCYP11B11584cytochrome P450, family 11, subfamily B, polypeptide 1
img NCI, Score=801, Pubmed Id: 11869873, UMLKSK CUI: C0206686
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206686Adrenocortical Carcinoma0self