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Details
Link-It Detail - Disease - Contact hypersensitivity
Debug Stats
  • ### Total Build Time: 9 ms 8.183 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 346 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 597 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 5.930 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.158 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Contact hypersensitivity C0162351
Definition (1)
Contact hypersensitivity is an inflammatory response induced by antigen-reactive T cells that are exposed to antigen on the skin surface (epidermis). Poison ivy is a frequent cause of such reactivity, due to the urushiol from the plant, as are a variety of antigens derived from industrial exposure (e.g. rubber, chromate, nickel). These antigens induce the appearance of Th1-like T cells, which presumably produce IFN to activate macrophages.
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanLOC100507436100507436
img GENERIF, Score=1000, Pubmed Id: 15381244, UMLKSK CUI: C0162351
HumanIL18BP10068interleukin 18 binding protein
img GENERIF, Score=901, Pubmed Id: 12874202, UMLKSK CUI: C0162351
HumanTNF7124tumor necrosis factor
img GAD, Score=1000, Pubmed Id: 11929587, UMLKSK CUI: C0162351
HumanCCL26347chemokine (C-C motif) ligand 2
img GENERIF, Score=1000, Pubmed Id: 11776402, UMLKSK CUI: C0162351
HumanCD47961CD47 molecule
img GENERIF, Score=1000, Pubmed Id: 18523271, UMLKSK CUI: C0162351
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0162351Contact hypersensitivity0self