Human | BLOC1S3 | 388552 | biogenesis of lysosomal organelles complex-1, subunit 3 | |
Human | IBD9 | 317669 | inflammatory bowel disease 9 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | IBD8 | 170595 | inflammatory bowel disease 8 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | IL23R | 149233 | interleukin 23 receptor | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | HPS4 | 89781 | Hermansky-Pudlak syndrome 4 | Hermansky-Pudlak syndrome type 4 (HPS-4) patients exhibited iris transillumination, variable hair and skin pigmentation, absent platelet dense bodies, and occasional pulmonary fibrosis and granulomatous colitis |
Human | HPS3 | 84343 | Hermansky-Pudlak syndrome 3 | |
Human | DTNBP1 | 84062 | dystrobrevin binding protein 1 | |
Human | HPS6 | 79803 | Hermansky-Pudlak syndrome 6 | |
Human | NOD2 | 64127 | nucleotide-binding oligomerization domain containing 2 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | MUC3B | 57876 | mucin 3B, cell surface associated | In ulcerative colitis and Crohn;s colitis tissues, MUC2 and MUC3 mRNA expression displayed a normal pattern regardless of whether the mucosa manifested active or quiescent inflammation. |
Human | IBD7 | 57042 | inflammatory bowel disease 7 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | IBD6 | 50942 | inflammatory bowel disease 6 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | IBD5 | 50941 | inflammatory bowel disease 5 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | IBD4 | 50608 | inflammatory bowel disease 4 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | IBD3 | 30829 | inflammatory bowel disease 3 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | HPS5 | 11234 | Hermansky-Pudlak syndrome 5 | |
Human | CD83 | 9308 | CD83 molecule | Because of epithelial growth factor receptor positivity of subepithelial cells epithelial growth factor receptor and CD45, CD68, or CD83 double fluorescence immunohistochemistry were performed on 16 freshly frozen samples from 8 severely active ulcerative colitis and 8 severely active Crohn;s colitis patients to describe lamina propria;s mononuclear cells, respectively. |
Human | DLG5 | 9231 | discs, large homolog 5 (Drosophila) | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | MADCAM1 | 8174 | mucosal vascular addressin cell adhesion molecule 1 | Involvement of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the pathogenesis of granulomatous colitis in rats. |
Human | VCAM1 | 7412 | vascular cell adhesion molecule 1 | The objectives of this study were to (1) assess the role of the 26S proteasome complex in regulating the expression of the inducible isoform of nitric oxide synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) in a model of chronic granulomatous colitis in vivo and (2) determine the role of the proteasome in regulating the inflammatory response observed in this model of chronic gut inflammation. |
Human | SLC22A4 | 6583 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |
Human | SELE | 6401 | selectin E | However, high levels of ELAM-1 were consistently found on endothelial surfaces in association with active inflammation in affected areas of colonic mucosa in patients with either ulcerative colitis (n = 27) or Crohn;s colitis (n = 9). |
Human | CEACAM6 | 4680 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | The NCA mRNA was detectable in 87% of the CRCs examined, with 92% of these expressing the NCA mRNA at higher levels than the tubulovillous adenoma and the specimen from Crohn;s colitis, whereas CEA was easily detected. |
Human | MUC3A | 4584 | mucin 3A, cell surface associated | In ulcerative colitis and Crohns colitis tissues, MUC2 and MUC3 mRNA expression displayed a normal pattern regardless of whether the mucosa manifested active or quiescent inflammation. |
Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | 35% of cases involve ileum only (ileitis), 45% of cases involve ileum and colon (ileocolitis), 20% of cases involve colon alone - rectum spared (granulomatous colitis) |