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Details
Link-It Detail - Disease - Malignant neoplasm of brain
Debug Stats
  • ### Total Build Time: 37 ms 54.827 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.007 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=9 ms Completed: 9 ms rowSize= 13.786 KB
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 38.459 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Malignant neoplasm of brain C0153633
Definition (1)

There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly.

Brain tumors can cause many symptoms. Some of the most common are

  • Headaches, usually worse in the morning
  • Nausea and vomiting
  • Changes in your ability to talk, hear or see
  • Problems with balance or walking
  • Problems with thinking or memory
  • Muscle jerking or twitching
  • Numbness or tingling in arms or legs

No one knows the exact causes of brain tumors. Doctors can seldom explain why one person develops a brain tumor and another does not.

NIH: National Cancer Institute

Relationships (45)

Relation Types:
diso_​to_​anat : 5
diso_​to_​diso : 40


Relationships:
associated_​with : 1
classifies : 1
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 2
is_​associated_​anatomic_​site_​of : 2
is_​not_​finding_​of_​disease : 1
isa : 15
location_​of : 1
mapped_​to : 18
related_​to : 2
used_​for : 1
Page Size
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  Page 1 of 2
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATlocation_ofimg Brain C0006104
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_associated_anatomic_site_ofimg Central Nervous System C0927232
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_associated_anatomic_site_ofimg Nervous System C0027763
DISO_to_DISOmapped_toimg ASTROCYTOMA C0004114
DISO_to_DISOmapped_toimg Anaplastic astrocytoma of brain C0349616
DISO_to_DISOmapped_toimg Anaplastic glioma of brain C1828201
DISO_to_DISOclinically_similarimg BRAIN NEOPLASM SECONDARY MULTIPLE C0518963
DISO_to_DISOmapped_toimg Benign glioma of brain C1997581
DISO_to_DISOrelated_toimg Brain Diseases C0006111
DISO_to_DISOisaimg Brain Germinoma C1332606
DISO_to_DISOmapped_toimg Brain Glioblastoma C0349543
DISO_to_DISOused_forimg Brain Neoplasms C0006118
DISO_to_DISOrelated_toimg Brain Neoplasms, Childhood C0220603
DISO_to_DISOmapped_toimg Brain Oligodendroglioma C0346286
DISO_to_DISOisaimg Brain Sarcoma C1332607
DISO_to_DISOmapped_toimg CNS lymphoma, primary C0280803
DISO_to_DISOclassifiesimg Cancer of brain and nervous system C0809971
DISO_to_DISOisaimg Cancer, Infratentorial C0751593
DISO_to_DISOisaimg Cancer, Supratentorial C0751589
DISO_to_DISOisaimg Carcinoma of brain C3163932
DISO_to_DISOmapped_toimg Cerebral Hemispheric Neuroblastoma C0559458
DISO_to_DISOmapped_toimg Ependymoma C0014474
DISO_to_DISOmapped_toimg Ependymoma of brain C0238029
Genes (57)

Species:
human : 57
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNKX6-284504
img NCI, Score=801, Pubmed Id: 11210186, UMLKSK CUI: C0153633
HumanBIRC657448baculoviral IAP repeat containing 6
img NCI, Score=801, Pubmed Id: 10544019, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 10544019, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 10544019, UMLKSK CUI: C0153633
HumanPANX256666pannexin 2
img GENERIF, Score=660, Pubmed Id: 16989724, UMLKSK CUI: C0153633
HumanBCCIP56647BRCA2 and CDKN1A interacting protein
img NCI, Score=801, Pubmed Id: 11313963, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 11313963, UMLKSK CUI: C0153633
HumanTNFRSF12A51330tumor necrosis factor receptor superfamily, member 12A
img NCI, Score=801, Pubmed Id: 15611130, UMLKSK CUI: C0153633
HumanGLTSCR129998glioma tumor suppressor candidate region gene 1
img GAD, Score=1000, Pubmed Id: 15834925, UMLKSK CUI: C0153633
HumanEPB41L323136erythrocyte membrane protein band 4.1-like 3
img NCI, Score=801, Pubmed Id: 12356905, UMLKSK CUI: C0153633
HumanADAMTS1311093ADAM metallopeptidase with thrombospondin type 1 motif, 13
img NCI, Score=801, Pubmed Id: 14644076, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 14644076, UMLKSK CUI: C0153633
img GENERIF, Score=988, Pubmed Id: 14644076, UMLKSK CUI: C0153633
HumanGLIPR111010GLI pathogenesis-related 1
img NCI, Score=801, Pubmed Id: 14871827, UMLKSK CUI: C0153633
HumanSPTLC110558serine palmitoyltransferase, long chain base subunit 1
img NCI, Score=801, Pubmed Id: 16968971, UMLKSK CUI: C0153633
HumanLGI19211leucine-rich, glioma inactivated 1
img NCI, Score=801, Pubmed Id: 9879993, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 9879993, UMLKSK CUI: C0153633
HumanSART19092squamous cell carcinoma antigen recognized by T cells
img NCI, Score=801, Pubmed Id: 15514588, UMLKSK CUI: C0153633
HumanIER38870immediate early response 3
img NCI, Score=801, Pubmed Id: 15691381, UMLKSK CUI: C0153633
HumanTMEFF18577transmembrane protein with EGF-like and two follistatin-like domains 1
img GENERIF, Score=1000, Pubmed Id: 12743596, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 12743596, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 12743596, UMLKSK CUI: C0153633
HumanRAD54L8438RAD54-like (S. cerevisiae)
img GAD, Score=1000, Pubmed Id: 12614485, UMLKSK CUI: C0153633
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img NCI, Score=801, Pubmed Id: 15880586, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 14595012, UMLKSK CUI: C0153633
HumanXRCC37517X-ray repair complementing defective repair in Chinese hamster cells 3
img GAD, Score=1000, Pubmed Id: 15313891, UMLKSK CUI: C0153633
HumanXRCC17515X-ray repair complementing defective repair in Chinese hamster cells 1
img GAD, Score=1000, Pubmed Id: 15313891, UMLKSK CUI: C0153633
HumanTP537157tumor protein p53
img GAD, Score=1000, Pubmed Id: 15313891, UMLKSK CUI: C0153633
HumanTMF17110TATA element modulatory factor 1
img NCI, Score=801, Pubmed Id: 15467733, UMLKSK CUI: C0153633
img NCI, Score=801, Pubmed Id: 15467733, UMLKSK CUI: C0153633
HumanTIMP27077TIMP metallopeptidase inhibitor 2
img NCI, Score=801, Pubmed Id: 10830727, UMLKSK CUI: C0153633
HumanTFRC7037transferrin receptor (p90, CD71)
img NCI, Score=801, Pubmed Id: 12095305, UMLKSK CUI: C0153633
HumanSLC2A16513solute carrier family 2 (facilitated glucose transporter), member 1
img GENERIF, Score=694, Pubmed Id: 15147968, UMLKSK CUI: C0153633
HumanSHH6469sonic hedgehog
img NCI, Score=801, Pubmed Id: 15488029, UMLKSK CUI: C0153633
HumanRAD515888RAD51 recombinase
img GAD, Score=1000, Pubmed Id: 15313891, UMLKSK CUI: C0153633
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0153633Malignant neoplasm of brain0self