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Details
Link-It Detail - Disease - Classical Hodgkin lymphoma, nodular sclerosis
Debug Stats
  • ### Total Build Time: 36 ms 24.011 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 388 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 515 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=28 ms Completed: 28 ms rowSize= 15.925 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 5.955 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Classical Hodgkin lymphoma, nodular sclerosis C0152268
Definition (1)
A subtype of classical Hodgkin lymphoma characterized by collagen bands surrounding lymphoid nodules. The lymphoid nodules contain lacunar and Reed-Sternberg cells. Mediastinal involvement occurs in 80% of patients. The prognosis of nodular sclerosis Hodgkin lymphoma is slightly better than that of mixed cellularity or lymphocyte depleted subtype. (WHO, 2001)
Relationships (68)

Relation Types:
diso_​to_​anat : 20
diso_​to_​diso : 38
diso_​to_​phen : 10


Relationships:
associated_​with : 5
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 8
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 16
may_​be_​abnormal_​cell_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 3
may_​be_​finding_​of_​disease : 16
may_​be_​molecular_​abnormality_​of_​disease : 5
may_​be_​normal_​cell_​origin_​of_​disease : 2
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cells, Reed-Sternberg C0085133
DISO_to_ANATis_abnormal_cell_of_diseaseimg Classical Reed-Sternberg Cell C1516595
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_abnormal_cell_of_diseaseimg Hodgkin Cell C1512478
DISO_to_ANATis_abnormal_cell_of_diseaseimg Lacunar Reed-Sternberg Cell C1517715
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Lymphatic System C0024235
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lymphatic Tissue C0024296
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATmay_be_normal_cell_origin_of_diseaseimg Mature B-Lymphocyte at the Germinal Center Stage of Differentiation C1513020
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mature Lymphocyte C1513026
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Mummified Cell C1513756
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Myeloid Cells C0887899
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Lymphocyte C1514011
DISO_to_ANATmay_be_normal_cell_origin_of_diseaseimg Peripheral (Post-Thymic) T-Lymphocyte C1519004
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Plasma Cells C0032112
DISO_to_DISOisaimg Adult Hodgkin's Nodular Sclerosis C0279541
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg Apoptotic Pathway Deregulation C1516046
DISO_to_DISOmay_be_finding_of_diseaseimg Body Weight decreased C0043096
DISO_to_DISOmay_be_finding_of_diseaseimg CD15-Positive Neoplastic Cells Present C1707093
DISO_to_DISOmay_be_finding_of_diseaseimg CD30+ Neoplastic Cells Present C1511421
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanEYA42070eyes absent homolog 4 (Drosophila)
img NCI, Score=801, Pubmed Id: 9440775, UMLKSK CUI: C0152268
HumanCSF1R1436colony stimulating factor 1 receptor
img NCI, Score=801, Pubmed Id: 2156611, UMLKSK CUI: C0152268
HumanCSF11435colony stimulating factor 1 (macrophage)
img NCI, Score=801, Pubmed Id: 2156611, UMLKSK CUI: C0152268
HumanMS4A1931membrane-spanning 4-domains, subfamily A, member 1
img NCI, Score=801, Pubmed Id: 11106083, UMLKSK CUI: C0152268
img NCI, Score=801, Pubmed Id: 16019516, UMLKSK CUI: C0152268
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0152268Classical Hodgkin lymphoma, nodular sclerosis0self