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Details
Link-It Detail - Disease - Liver Failure
Debug Stats
  • ### Total Build Time: 281 ms 45.620 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 456 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 557 bytes
  • CONCEPT_CHILDREN gt=7 ms Completed: 7 ms rowSize= 998 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.508 KB
  • CONCEPT_RELATIONSHIPS gt=190 ms Completed: 190 ms rowSize= 14.538 KB
  • CONCEPT_GENES gt=50 ms Completed: 50 ms rowSize= 25.936 KB
  • CONCEPT_XREFS gt=9 ms Completed: 9 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Liver Failure C0085605
Definition (1)
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
Semantic Types (1)
Pathologic Function (T046)
Parents (1)
img Hepatic Insufficiency C1306571
Children (2)
img Hepatic Encephalopathy C0019151
img Liver Failure, Acute C0162557
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Liver Diseases C00238954img Hepatic Insufficiency C1306571
Relationships (117)

Relation Types:
diso_​to_​anat : 16
diso_​to_​chem : 32
diso_​to_​diso : 60
diso_​to_​phen : 1
diso_​to_​phys : 8


Relationships:
none : 92
induces : 10
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 8
location_​of : 1
mapped_​to : 1
may_​diagnose : 1
Page Size
Current 25
  Page 1 of 5
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO147img Complication Aspects C1171258
DISO_to_DISO129img chemically induced C0007994
DISO_to_DISO124img Complication Aspects C1171258
DISO_to_DISO93img chemically induced C0007994
DISO_to_ANAT90img In Blood C0005768
DISO_to_ANAT86img In Blood C0005768
DISO_to_DISO73img Liver Cirrhosis C0023890
DISO_to_ANAT61img Liver C0023884
DISO_to_DISO57img Liver Neoplasms C0023903
DISO_to_DISO55img Liver Cirrhosis C0023890
DISO_to_ANAT53img Liver C0023884
DISO_to_DISO50img COMPL POSTOP C0032787
DISO_to_DISO49img Liver Neoplasms C0023903
DISO_to_ANAT44img Hepatocytes C0227525
DISO_to_DISO37img COMPL POSTOP C0032787
DISO_to_ANAT34img Hepatocyte C0227525
DISO_to_DISO32img Chronic Hepatitis B C0524909
DISO_to_DISO30img Hepatitis C C0019196
DISO_to_DISO29img Hepatitis B C0019163
DISO_to_DISO28img Carcinoma, Hepatocellular C2239176
DISO_to_DISO28img Renal Insufficiency C1565489
DISO_to_DISO27img Carcinoma, Hepatocellular C2239176
DISO_to_DISO27img Hepatitis B C0019163
DISO_to_DISO27img Hepatitis C C0019196
DISO_to_DISO25img Renal Insufficiency C1565489
Genes (50)

Species:
human : 50
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNHLRC1378884NHL repeat containing 1
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanNDUFAF291942NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanGFM185476G elongation factor, mitochondrial 1
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanHSD3B780270hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
img OMIM, Score=882, UMLKSK CUI: C0085605
HumanC20orf779133
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanC10orf256652chromosome 10 open reading frame 2
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanNDUFAF429078NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanACAD928976acyl-CoA dehydrogenase family, member 9
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanRGN9104regucalcin
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanSUCLA28803succinate-CoA ligase, ADP-forming, beta subunit
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanEPM2A7957epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img GENERIF, Score=1000, Pubmed Id: 17964871, UMLKSK CUI: C0085605
HumanVIP7432vasoactive intestinal peptide
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanTK27084thymidine kinase 2, mitochondrial
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanS100B6285S100 calcium binding protein B
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanS100A126283S100 calcium binding protein A12
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanPOLG5428polymerase (DNA directed), gamma
img OMIM, Score=1000, UMLKSK CUI: C0085605
HumanREG3A5068regenerating islet-derived 3 alpha
img GENERIF, Score=1000, Pubmed Id: 16116631, UMLKSK CUI: C0085605
HumanNPC14864Niemann-Pick disease, type C1
img OMIM, Score=882, UMLKSK CUI: C0085605
HumanNPY4852neuropeptide Y
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanNOS24843nitric oxide synthase 2, inducible
INFERRED, Score=800, UMLKSK CUI: C0085605
HumanNDUFS64726NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
img OMIM, Score=1000, UMLKSK CUI: C0085605
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0085605Liver Failure0self