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Details
Link-It Detail - Disease - Rheumatic Fever
Debug Stats
  • ### Total Build Time: 67 ms 39.966 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 328 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 479 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.391 KB
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 1.397 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 5.351 KB
  • CONCEPT_RELATIONSHIPS gt=42 ms Completed: 42 ms rowSize= 13.770 KB
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 15.909 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Rheumatic Fever C0035436
Definition (1)
A febrile disease occurring as a delayed sequela of infections with STREPTOCOCCUS PYOGENES. It is characterized by multiple focal inflammatory lesions of the connective tissue structures, such as the heart, blood vessels, and joints (POLYARTHRITIS) and brain, and by the presence of ASCHOFF BODIES in the myocardium and skin.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (3)
img Streptococcal Infections C0038395
img Arthritis C0003864
img Rheumatic Diseases C0035435
Children (3)
img Rheumatic Heart Disease C0035439
img Wisslers Syndrome C0043195
img Rheumatic Nodule C0035441
Ancestral Roots
RootRoot Plus OneDepthParent
img Bacterial Infections and Mycoses C0004615img Bacterial Infections C00046235img Streptococcal Infections C0038395
img Musculoskeletal Diseases C0026857img Joint Diseases C00224084img Arthritis C0003864
img Musculoskeletal Diseases C0026857img Rheumatic Diseases C00354353img Rheumatic Diseases C0035435
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097824img Rheumatic Diseases C0035435
Relationships (96)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 56
diso_​to_​diso : 38


Relationships:
none : 24
associated_​with : 4
clinically_​similar : 4
isa : 6
location_​of : 2
mapped_​to : 1
may_​prevent : 8
may_​treat : 47
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO44img Complication Aspects C1171258
DISO_to_DISO43img Complication Aspects C1171258
DISO_to_DISO32img Rheumatic Heart Disease C0035439
DISO_to_DISO32img Streptococcal Infections C0038395
DISO_to_DISO24img Streptococcal Infections C0038395
DISO_to_DISO23img Rheumatic Heart Disease C0035439
DISO_to_ANATlocation_ofimg Articular system C0392905
DISO_to_ANATlocation_ofimg Heart C0018787
DISO_to_CHEMmay_treatimg 2-(Acetyloxy)benzoic Acid C0004057
DISO_to_CHEMmay_treatimg 4 ML penicillin G benzathine 600000 UNT/ML Prefilled Syringe C0873452
DISO_to_CHEMmay_treatimg ACETYLSALICYLATE SODIUM C0981808
DISO_to_CHEMmay_treatimg ASA 162 MG Enteric Coated Tablet C0691152
DISO_to_CHEMmay_treatimg ASA 165 MG Enteric Coated Tablet C0974603
DISO_to_CHEMmay_treatimg ASA 165 MG Oral Tablet C0974602
DISO_to_CHEMmay_treatimg ASA 228 MG Chewing Gum C0704929
DISO_to_CHEMmay_treatimg ASA 300 MG Rectal Suppository C0691133
DISO_to_CHEMmay_treatimg ASA 325 MG Oral Capsule C0691136
DISO_to_CHEMmay_treatimg ASA 325 MG Rectal Suppository C0691138
DISO_to_CHEMmay_treatimg ASA 486 MG Oral Tablet C0691140
DISO_to_CHEMmay_treatimg ASA 488 MG Enteric Coated Tablet C0692316
DISO_to_CHEMmay_treatimg ASA 500 MG Enteric Coated Tablet C0974611
DISO_to_CHEMmay_treatimg ASA 60 MG Rectal Suppository C0691143
DISO_to_CHEMmay_treatimg ASA 600 MG Rectal Suppository C0691144
DISO_to_CHEMmay_treatimg ASA 65 MG Chewable Tablet C0974616
DISO_to_CHEMmay_treatimg ASA 65 MG Rectal Suppository C0981219
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanMASP210747mannan-binding lectin serine peptidase 2
img GENERIF, Score=1000, Pubmed Id: 18295674, UMLKSK CUI: C0035436
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 16046099, UMLKSK CUI: C0035436
HumanTLR47099toll-like receptor 4
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanTLR27097toll-like receptor 2
img GAD, Score=1000, Pubmed Id: 15968536, UMLKSK CUI: C0035436
HumanTGFB17040transforming growth factor, beta 1
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanRHD6007Rh blood group, D antigen
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanRHCE6006Rh blood group, CcEe antigens
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanMBL24153mannose-binding lectin (protein C) 2, soluble
img GENERIF, Score=1000, Pubmed Id: 18602696, UMLKSK CUI: C0035436
HumanLTBP14052latent transforming growth factor beta binding protein 1
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanIL63569interleukin 6 (interferon, beta 2)
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanHLA-DRB13123
img GAD, Score=1000, Pubmed Id: 15789899, UMLKSK CUI: C0035436
HumanHLA-DQB13119
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanHLA-DQA13117
img GAD, Score=1000, Pubmed Id: 15789899, UMLKSK CUI: C0035436
HumanFCGR3B2215Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
img GAD, Score=1000, Pubmed Id: 15369725, UMLKSK CUI: C0035436
img GENERIF, Score=1000, Pubmed Id: 15369725, UMLKSK CUI: C0035436
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
img GAD, Score=1000, Pubmed Id: 15369725, UMLKSK CUI: C0035436
img GENERIF, Score=1000, Pubmed Id: 15369725, UMLKSK CUI: C0035436
HumanDUSP11843dual specificity phosphatase 1
INFERRED, Score=800, UMLKSK CUI: C0035436
HumanMAPK141432mitogen-activated protein kinase 14
INFERRED, Score=800, UMLKSK CUI: C0035436
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0035436Rheumatic Fever0self