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Details
Link-It Detail - Disease - Retinopathy of Prematurity
Debug Stats
  • ### Total Build Time: 52 ms 27.855 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 511 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 2.819 KB
  • CONCEPT_RELATIONSHIPS gt=34 ms Completed: 34 ms rowSize= 13.573 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 8.270 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Retinopathy of Prematurity C0035344
Definition (1)
bilateral retinopathy typically occurring in premature infants treated with high concentrations of oxygen; characterized by vascular dilation, proliferation, and tortuosity, edema, and retinal detachment with ultimate conversion of the retina into a fibrous mass; usually growth of the eye is arrested and may result in microophthalmia; blindness may occur.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Retinal Diseases C0035309
img Infant, Premature, Diseases C0021295
Ancestral Roots
RootRoot Plus OneDepthParent
img Eye Diseases C0015397img Retinal Diseases C00353093img Retinal Diseases C0035309
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Infant, Newborn, Diseases C00212904img Infant, Premature, Diseases C0021295
Relationships (56)

Relation Types:
diso_​to_​anat : 8
diso_​to_​chem : 17
diso_​to_​diso : 27
diso_​to_​phen : 2
diso_​to_​phys : 2


Relationships:
none : 37
associated_​with : 1
classifies : 2
expanded_​form_​of : 1
induces : 7
is_​associated_​anatomic_​site_​of : 2
isa : 5
related_​to : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO81img Complication Aspects C1171258
DISO_to_ANAT75img Retinal Vessels C0035330
DISO_to_DISO68img NEOVASC RETINAL C0035320
DISO_to_CHEM67img ANGIOGENESIS INHIB C0596087
DISO_to_DISO65img Complication Aspects C1171258
DISO_to_DISO47img Animal Disease Models C0012644
DISO_to_PHEN43img genetic aspects C0017399
DISO_to_CHEM42img Antibodies, Monoclonal C0003250
DISO_to_DISO42img NEOVASC RETINAL C0035320
DISO_to_ANAT41img Retina C0035298
DISO_to_CHEM41img Vascular Endothelial Growth Factor A C0078058
DISO_to_CHEM39img Oxygen C0030054
DISO_to_DISO36img INFANT VLBW C0282667
DISO_to_DISO36img Retinal Detachment C0035305
DISO_to_ANAT30img Retinal Vessels C0035330
DISO_to_DISO29img INFANT VLBW C0282667
DISO_to_ANAT28img In Blood C0005768
DISO_to_CHEM28img Oxygen C0030054
DISO_to_DISO27img Retinal Detachment C0035305
DISO_to_ANAT23img In Blood C0005768
DISO_to_PHEN19img genetic aspects C0017399
DISO_to_CHEM18img Antibodies, Humanized C2985546
DISO_to_CHEM17img Insulin-Like Growth Factor I C0021665
DISO_to_DISO17img chemically induced C0007994
DISO_to_PHYS17img Visual Acuity C0042812
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanCNKSR222866connector enhancer of kinase suppressor of Ras 2
img GENERIF, Score=1000, Pubmed Id: 14597674, UMLKSK CUI: C0035344
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=861, Pubmed Id: 16877277, UMLKSK CUI: C0035344
img GENERIF, Score=861, Pubmed Id: 17119993, UMLKSK CUI: C0035344
img GENERIF, Score=861, Pubmed Id: 18546007, UMLKSK CUI: C0035344
HumanINSL33640insulin-like 3 (Leydig cell)
img GENERIF, Score=812, Pubmed Id: 19086273, UMLKSK CUI: C0035344
HumanIGF1R3480insulin-like growth factor 1 receptor
img GENERIF, Score=1000, Pubmed Id: 16362313, UMLKSK CUI: C0035344
HumanACE1636angiotensin I converting enzyme
img GENERIF, Score=861, Pubmed Id: 12169829, UMLKSK CUI: C0035344
HumanANGPT2285angiopoietin 2
img GENERIF, Score=1000, Pubmed Id: 16877277, UMLKSK CUI: C0035344
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0035344Retinopathy of Prematurity0self