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Details
Link-It Detail - Disease - Renal Osteodystrophy
Debug Stats
  • ### Total Build Time: 32 ms 24.799 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 338 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 451 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.823 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 9.181 KB
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 9.289 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 2.362 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.154 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Renal Osteodystrophy C0035086
Definition (1)
Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (4)
img Kidney Diseases C0022658
img Bone Diseases, Metabolic C0005944
img Rickets C0035579
img Hyperparathyroidism, Secondary C0020503
Ancestral Roots
RootRoot Plus OneDepthParent
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208875img Kidney Diseases C0022658
img Male Urogenital Diseases C1720894img Urologic Diseases C00420754img Kidney Diseases C0022658
img Musculoskeletal Diseases C0026857img Bone Diseases C00059404img Bone Diseases, Metabolic C0005944
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255175img Rickets C0035579
img Nutritional and Metabolic Diseases C0028715img Nutrition Disorders C00287098img Rickets C0035579
img Musculoskeletal Diseases C0026857img Bone Diseases C00059405img Rickets C0035579
img Endocrine System Diseases C0014130img Parathyroid Diseases C00305175img Hyperparathyroidism, Secondary C0020503
Relationships (22)

Relation Types:
diso_​to_​anat : 4
diso_​to_​chem : 3
diso_​to_​diso : 13
diso_​to_​phys : 2


Relationships:
none : 16
classifies : 2
mapped_​to : 4
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO87img Kidney Failure, Chronic C0022661
DISO_to_DISO72img Kidney Failure, Chronic C0022661
DISO_to_ANAT58img In Blood C0005768
DISO_to_CHEM44img Parathyroid Hormone C0030520
DISO_to_DISO32img Complication Aspects C1171258
DISO_to_ANAT29img BONE BONES C0005931
DISO_to_DISO28img Complication Aspects C1171258
DISO_to_ANAT27img In Blood C0005768
DISO_to_DISO23img HYPERPARATHYROIDISM SECOND C0020503
DISO_to_DISO22img HYPERPARATHYROIDISM SECOND C0020503
DISO_to_DISO18img Chronic Kidney Insufficiency C0403447
DISO_to_ANAT15img BONE BONES C0005931
DISO_to_PHYS14img Bone Remodeling C0085268
DISO_to_CHEM13img Parathyroid Hormone C0030520
DISO_to_CHEM11img Vitamin D C0042866
DISO_to_PHYS11img Bone Density C0005938
DISO_to_DISOmapped_toimg DWARFISM, RENAL C0221041
DISO_to_DISOclassifiesimg Other and unspecified diseases of kidney and ureters C0156258
DISO_to_DISOclassifiesimg Other diseases of kidney and ureters C0810036
DISO_to_DISOmapped_toimg Renal Osteodystrophy C0035086
DISO_to_DISOmapped_toimg Renal rickets C1527410
DISO_to_DISOmapped_toimg Renal secondary osteodystrophia fibrosa C0268812
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanOCRL4952oculocerebrorenal syndrome of Lowe
img OMIM, Score=1000, UMLKSK CUI: C0035086
HumanACP554acid phosphatase 5, tartrate resistant
img GENERIF, Score=1000, Pubmed Id: 17357281, UMLKSK CUI: C0035086
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0035086Renal Osteodystrophy0self