Human | STOX1 | 219736 | storkhead box 1 | |
Human | NEWENTRY | 192343 | Record to support submission of GeneRIFs for a gene not in Gene (human; man). | C4d positive chronic rejection is very common, associated with proteinuria, and has a poor outcome[C4d] |
Human | LMNB2 | 84823 | lamin B2 | |
Human | AMN | 81693 | amnion associated transmembrane protein | |
Human | HPSE2 | 60495 | heparanase 2 | Data suggest that loss of modified heparan sulphate in the GBM is mediated by an increased heparanase presence and may play a role in the pathogenesis of diabetes-induced proteinuria |
Human | ACE2 | 59272 | angiotensin I converting enzyme 2 | Relationship between urinary mRNA expression of ACE2 and the degree of proteinuria in type 2 diabetic nephropathy |
Human | PEX26 | 55670 | peroxisomal biogenesis factor 26 | INFERRED, Score=800, UMLKSK CUI: C0033687 |
Human | NT5C3 | 51251 | 5'-nucleotidase, cytosolic III | INFERRED, Score=800, UMLKSK CUI: C0033687 |
Human | PLCE1 | 51196 | phospholipase C, epsilon 1 | |
Human | SMARCAL1 | 50485 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | |
Human | NPHP3 | 27031 | nephronophthisis 3 (adolescent) | |
Human | MMACHC | 25974 | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | |
Human | NIPBL | 25836 | Nipped-B homolog (Drosophila) | |
Human | KIF1B | 23095 | kinesin family member 1B | |
Human | SYNPO | 11346 | synaptopodin | We conclude that down-regulation of nephrin and synaptopodin is associated with proteinuria in women with preeclampsia |
Human | ADAMTS13 | 11093 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 | |
Human | HPSE | 10855 | heparanase | Heparanase mRNA may be important to the loss of glomerular negative charge in GBM and lead to proteinuria in steroid responsive nephrotic syndrome HPSE is involved in the pathogenesis of proteinuria in overt diabetic nephropathy by degradation of heparan sulfates |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | Increased serum adiponectin might be the reflection of a compensatory response to nephrotic state characterized by massive proteinuria, hypoalbuminemia and hyperlipidemia |
Human | PEX3 | 8504 | peroxisomal biogenesis factor 3 | INFERRED, Score=800, UMLKSK CUI: C0033687 |
Human | CUBN | 8029 | cubilin (intrinsic factor-cobalamin receptor) | proteinuria was due to the lack of cubilin function needed for tubular reabsorption of some, but not all, proteins of the primary urine |
Human | NPHS2 | 7827 | nephrosis 2, idiopathic, steroid-resistant (podocin) | NPHS2 gene mutations are not a major cause of chronic renal insufficiency caused by sporadic SRNS or heavy proteinuria in Japanese children Gene mutations for podocin cause the damage of filtration barrier of glomerulus and proteinuria in consequence mutation is associated with early onset of proteinuria and variable renal lesions Mutations of NPHS1 or NPHS2, the genes encoding for nephrin and podocin, lead to early onset of heavy proteinuria, and rapid progression to end-stage renal disease, suggesting that both proteins are essential for the integrity of the glomerular filter |
Human | WT1 | 7490 | Wilms tumor 1 | Posttransplant recurrence of proteinuria in a case of focal segmental glomerulosclerosis is associated with WT1 mutation |
Human | VHL | 7428 | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase | |
Human | VEGFA | 7422 | vascular endothelial growth factor A | The VEGF -460C polymorphism is a positive independent predictive factor for the development of proliferative diabetic retinopathy, but not proteinuria |
Human | UPK3A | 7380 | uroplakin 3A | |