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Details
Link-It Detail - Disease - Polyradiculoneuropathy
Debug Stats
  • ### Total Build Time: 46 ms 33.429 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 583 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=6 ms Completed: 6 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.418 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.891 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 5.402 KB
  • CONCEPT_RELATIONSHIPS gt=18 ms Completed: 18 ms rowSize= 10.022 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 12.372 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Polyradiculoneuropathy C0032587
Polyradiculoneuropathies
Definition (1)
Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (3)
img Polyneuropathies C0152025
img Autoimmune Diseases of the Nervous System C0751871
img Demyelinating Diseases C0011303
Children (4)
img Polyradiculopathy C0032586
img Guillain-Barre Syndrome C0018378
img Polyradiculoneuropathy, Chronic Inflammatory Demyelinating C0393819
img Hereditary Sensory and Autonomic Neuropathies C0027889
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Neuromuscular Diseases C00278685img Polyneuropathies C0152025
img Immune System Diseases C0021053img Autoimmune Diseases C00043644img Autoimmune Diseases of the Nervous System C0751871
img Nervous System Diseases C0027765img Autoimmune Diseases of the Nervous System C07518713img Autoimmune Diseases of the Nervous System C0751871
img Nervous System Diseases C0027765img Demyelinating Diseases C00113033img Demyelinating Diseases C0011303
Relationships (24)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 6
diso_​to_​diso : 15
diso_​to_​phen : 1


Relationships:
none : 18
isa : 5
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO16img Complication Aspects C1171258
DISO_to_DISO11img Complication Aspects C1171258
DISO_to_DISO10img chemically induced C0007994
DISO_to_DISO9img Peripheral Nervous System Diseases C0031117
DISO_to_CHEM7img Immunoglobulins, Intravenous C0085297
DISO_to_ANAT6img Peripheral Nerves C0031119
DISO_to_CHEM6img Antibodies, Monoclonal C0003250
DISO_to_DISO6img DIS OCCUP C0028797
DISO_to_DISO6img EXPOSURE OCCUP C0028798
DISO_to_DISO6img Peripheral Nervous System Diseases C0031117
DISO_to_ANAT5img Peripheral Nerves C0031119
DISO_to_CHEM5img Abs - Autoantibodies C0004358
DISO_to_CHEM5img Immunoglobulin M C0020861
DISO_to_CHEM5img Immunologic Factors C0021054
DISO_to_CHEM5img Myelin Associated Glycoprotein C0129439
DISO_to_DISO5img Guillain-Barre Syndrome C0018378
DISO_to_DISO5img chemically induced C0007994
DISO_to_PHEN5img genetic aspects C0017399
DISO_to_DISOisaimg Canine polyradiculoneuritis C0277512
DISO_to_DISOisaimg Fisher Syndrome C0393799
DISO_to_DISOisaimg Guillain-Barre Syndrome C0018378
DISO_to_DISOpermuted_term_ofimg Polyradiculoneuropathies C0032587
DISO_to_DISOisaimg Polyradiculoneuropathy, Chronic Inflammatory Demyelinating C0393819
DISO_to_DISOisaimg Subacute idiopathic demyelinating polyradiculoneuropathy C0456517
Genes (20)

Species:
human : 20
SpeciesGeneGeneIdGene NameEvidence
HumanST6GALNAC427090ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanYWHAQ10971tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanCTNNAL18727catenin (cadherin-associated protein), alpha-like 1
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanIKBKAP8518inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanTLR47099toll-like receptor 4
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanS100A126283S100 calcium binding protein A12
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanMBL24153mannose-binding lectin (protein C) 2, soluble
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanIL12B3593interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanHLA-DRB13123
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanHLA-DQB13119
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanHLA-DQA13117
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanGFAP2670glial fibrillary acidic protein
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanFCGR3B2215Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanFCGR3A2214Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanCD14929CD14 molecule
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanFAS355Fas cell surface death receptor
INFERRED, Score=800, UMLKSK CUI: C0032587
HumanAPOE348apolipoprotein E
INFERRED, Score=800, UMLKSK CUI: C0032587
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0032587Polyradiculoneuropathy0self