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Details
Link-It Detail - Disease - Plague
Debug Stats
  • ### Total Build Time: 36 ms 18.658 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 310 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.374 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
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  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 1.519 KB
  • CONCEPT_RELATIONSHIPS gt=19 ms Completed: 19 ms rowSize= 13.518 KB
  • CONCEPT_GENES gt=2 ms Completed: 2 ms rowSize= 45 bytes
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.141 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Plague C0032064
Definition (1)

Plague is an infection caused by the bacterium Yersinia pestis. The bacteria are found mainly in rats and in the fleas that feed on them. People and other animals can get plague from rat or flea bites. Historically, plague destroyed entire civilizations. In the 1300s, the "Black Death," as it was called, killed approximately one-third of Europe's population. Today plague is uncommon. This is largely due to better living conditions and antibiotics.

There are three forms of plague:

  • Bubonic, which causes the tonsils, adenoids, spleen and thymus to become inflamed. Symptoms include fever, aches, chills and tender lymph glands
  • Septicemic, in which bacteria multiply in the blood. It causes fever, chills, shock and bleeding under the skin or other organs
  • Pneumonic, in which the bacteria enter the lungs and cause pneumonia. People with the infection can spread this form to others. This type could be a bioterror agent

Treatment for plague is a strong antibiotic. There is no vaccine for plague.

NIH: National Institute of Allergy and Infectious Diseases

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Yersinia Infections C0043407
Ancestral Roots
RootRoot Plus OneDepthParent
img Bacterial Infections and Mycoses C0004615img Bacterial Infections C00046236img Yersinia Infections C0043407
Relationships (42)

Relation Types:
diso_​to_​chem : 19
diso_​to_​diso : 15
diso_​to_​gene : 1
diso_​to_​phen : 7


Relationships:
none : 24
associated_​with : 1
classifies : 1
clinically_​similar : 2
isa : 4
may_​prevent : 2
may_​treat : 4
related_​to : 2
use : 1
used_​for : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM81img Plague Vaccine C0032066
DISO_to_PHEN73img Disease Outbreaks C0012652
DISO_to_PHEN63img Disease Outbreaks C0012652
DISO_to_CHEM49img ANTIGENS BACT C0003321
DISO_to_CHEM42img BACT GENE PRODUCT C0004627
DISO_to_CHEM33img Plague Vaccine C0032066
DISO_to_CHEM33img Pore Forming Cytotoxic Proteins C1720905
DISO_to_DISO32img Disease, Rodent C0035801
DISO_to_CHEM26img ANTIGENS BACT C0003321
DISO_to_CHEM23img BACT GENE PRODUCT C0004627
DISO_to_PHEN22img genetic aspects C0017399
DISO_to_CHEM19img ANTIBODIES BACT C0003244
DISO_to_CHEM18img Factors, Pathogenicity C1136170
DISO_to_CHEM14img ANTIBODIES BACT C0003244
DISO_to_CHEM14img BACT OUTER MEMBRANE PROTEINS C0004625
DISO_to_DISO14img Anthrax C0003175
DISO_to_PHEN14img genetic aspects C0017399
DISO_to_CHEM12img Anti-Bacterial Agents C0279516
DISO_to_PHEN12img Epidemic C0014499
DISO_to_DISO11img Disease, Rodent C0035801
DISO_to_CHEM10img Anti-Bacterial Agents C0279516
DISO_to_DISO10img Deer fly fever C0041351
DISO_to_GENE10img BACT GENOME C0085238
DISO_to_PHEN10img Climate C0008946
DISO_to_CHEMmay_treatimg Bis-(4-O-(2-O-(2-desoxy-2-methylamino-alpha-L-glucopyranosyl)-alpha-L-streptosyl)-L-streptidin)-trisulfat C0038426
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0032064Plague0self