Human | NACC1 | 112939 | nucleus accumbens associated 1, BEN and BTB (POZ) domain containing | NAC-1 expression is higher in ovarian carcinoma cells in effusions compared with their solid tumor counterparts |
Human | MUC16 | 94025 | mucin 16, cell surface associated | Our results suggest that an immunohistochemical panel consisting of TTF-1, CEA, CA-125, and OCT-4 is helpful in distinguishing most pulmonary and ovarian carcinomas with clear cell features |
Human | CGB5 | 93659 | chorionic gonadotropin, beta polypeptide 5 | HCG-beta gene was found in patients with ovarian carcinoma, whereas noncancerous tissue demonstrated lack of the hormone expression |
Human | RBM17 | 84991 | RNA binding motif protein 17 | Stable transfection of RBM17 (SPF45) into A2780 ovarian carcinoma cells conferred drug resistance to carboplatin, vinorelbine, doxorubicin, etoposide, mitoxantrone, vincristine, gemcitabine, and pemetrexed |
Human | CHP2 | 63928 | calcineurin-like EF-hand protein 2 | overexpression of the CHP2 gene affects the biological behavior of ovarian cancer cell line OVCAR3 and is one of key mechanisms for ovarian carcinoma progression |
Human | DIABLO | 56616 | diablo, IAP-binding mitochondrial protein | Expression of Smac/DIABLO can stimulate the intrinsic pathway of apoptosis in ovarian carcinoma without damaging normal ovarian tissue and therefore has therapeutic potential |
Human | UNC45A | 55898 | unc-45 homolog A (C. elegans) | elevated GC UNC-45 protein expression in ovarian carcinoma proliferation and metastasis |
Human | LAPTM4B | 55353 | lysosomal protein transmembrane 4 beta | LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma |
Human | WWOX | 51741 | WW domain containing oxidoreductase | WWOX protein expression is highly variable among ovarian carcinoma histotypes and may have a role in disease progression |
Human | IP6K2 | 51447 | inositol hexakisphosphate kinase 2 | IHPK2 over expression enhances sensitivity of ovarian carcinoma cells to radiation, IFN-beta, caspase 8 and DR4 |
Human | KLRK1 | 22914 | killer cell lectin-like receptor subfamily K, member 1 | findings show macrophage migration inhibitory factor may contribute to the immune escape of ovarian carcinoma by transcriptionally down-regulating NKG2D in vitro and in vivo which impairs NK cell cytotoxicity toward tumor cells |
Human | KLK11 | 11012 | kallikrein-related peptidase 11 | Title:Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma.|Association:Not Found|Conclusion:Not Found Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma |
Human | CHL1 | 10752 | cell adhesion molecule L1-like | L1 could drive progression by enhancing cell migration and tumor growth in ovarian carcinoma |
Human | IGF2BP1 | 10642 | insulin-like growth factor 2 mRNA binding protein 1 | IMP1 is an oncogenic factor that is involved in promoting elevated proliferation by stabilizing the c-myc mRNA in ovarian carcinoma cells |
Human | SPON1 | 10418 | spondin 1, extracellular matrix protein | expression profile of VSGP/F-spondin identifies this molecule as a potential diagnostic marker or target for developing therapeutic strategies to treat ovarian carcinoma |
Human | WFDC2 | 10406 | WAP four-disulfide core domain 2 | This protein's gene is amplified in ovarian carcinoma; it can serve as a tumor marker for this disease |
Human | OSMR | 9180 | oncostatin M receptor | expression and evidence for STAT3 activation in human ovarian carcinomas |
Human | TSC22D1 | 8848 | TSC22 domain family, member 1 | interaction between fortilin and TSC-22 prevents apoptosis via the destabilization of TSC-22 in ovarian carcinoma cells |
Human | CFLAR | 8837 | CASP8 and FADD-like apoptosis regulator | the inhibitory protein c-FLIP(L) is involved in resistance to CD95-mediated apoptosis in ovarian carcinoma cells with wild-type p53 |
Human | CXCR4 | 7852 | chemokine (C-X-C motif) receptor 4 | CXCR4 expression is an important prognostic factor in ovarian carcinoma |
Human | VTN | 7448 | vitronectin | ability of ovarian carcinoma cells to bind to peritoneal mesothelium in vitro and strongly suggest that vitronectin and its receptors contribute to this crucial event |
Human | EZR | 7430 | ezrin | data imply that ezrin is necessary for tumor cell invasion, and the better prognosis of ovarian carcinomas lacking ezrin is probably related to their impaired invasion |
Human | VHL | 7428 | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase | although LOH at the VHL gene locus was frequent in ovarian carcinomas, there is no significant correlation between LOH & loss of VHL expression; in 22 clear cell carcinomas, VHL expression showed negative correlation with nuclear expression of HIF-1alpha |
Human | VEGFC | 7424 | vascular endothelial growth factor C | Her-2/NEU oncogene is essential for the regulation of VEGF-C in ovarian carcinoma; p38 MAPK and NF-kappa B are critically involved in the transcriptional activation of the VEGF-C gene by Her-2/NEU |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Click here to display 8 evidence detail records. |