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Details
Link-It Detail - Disease - Osteosarcoma
Debug Stats
  • ### Total Build Time: 168 ms 61.856 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 375 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 983 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 997 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.062 KB
  • CONCEPT_RELATIONSHIPS gt=100 ms Completed: 100 ms rowSize= 16.646 KB
  • CONCEPT_GENES gt=55 ms Completed: 55 ms rowSize= 37.179 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Osteosarcoma C0029463
Definition (1)
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Neoplasms, Bone Tissue C0206639
img Sarcoma C1261473
Children (2)
img Osteosarcoma, Juxtacortical C0206642
img Sarcoma, Ewing C0553580
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Neoplasms, Bone Tissue C0206639
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097825img Neoplasms, Bone Tissue C0206639
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Sarcoma C1261473
Relationships (212)

Relation Types:
diso_​to_​anat : 35
diso_​to_​chem : 70
diso_​to_​diso : 84
diso_​to_​gene : 6
diso_​to_​phen : 2
diso_​to_​phys : 15


Relationships:
none : 148
clinically_​similar : 1
eo_​disease_​maps_​to_​human_​disease : 16
gene_​associated_​with_​disease : 5
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​not_​normal_​tissue_​origin_​of_​disease : 1
isa : 7
mapped_​to : 2
may_​treat : 15
permuted_​term_​of : 1
use : 1
Page Size
Current 25
  Page 1 of 9
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO1351img Bone Neoplasms C0005967
DISO_to_DISO989img Bone Neoplasms C0005967
DISO_to_PHEN361img genetic aspects C0017399
DISO_to_PHEN234img genetic aspects C0017399
DISO_to_CHEM154img Antineoplastic Agents C0003392
DISO_to_DISO128img Lung Neoplasms C0024121
DISO_to_PHYS111img Apoptosis C0162638
DISO_to_DISO98img Lung Neoplasms C0024121
DISO_to_DISO97img CANINE DIS C0012979
DISO_to_DISO95img Complication Aspects C1171258
DISO_to_PHYS83img GENE EXPRESSION REG NEOPL C0017268
DISO_to_DISO81img CANINE DIS C0012979
DISO_to_DISO74img Complication Aspects C1171258
DISO_to_PHYS74img Apoptosis C0162638
DISO_to_DISO73img Femoral Neoplasms C0015807
DISO_to_CHEM71img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM70img Antineoplastic Agents C0003392
DISO_to_DISO65img Sarcoma, Ewing C0553580
DISO_to_DISO56img Ewings sarcoma C0553580
DISO_to_DISO56img FEMORAL NEOPL C0015807
DISO_to_ANAT47img Bone structure of tibia C0040184
DISO_to_DISO44img Chondrosarcoma C0008479
DISO_to_PHYS44img ANTINEOPL AGENT RESISTANCE C0282588
DISO_to_PHYS39img Signal Transduction C0037083
DISO_to_ANAT38img Bone structure of tibia C0040184
Genes (390)

Species:
human : 382
mouse : 8
Page Size
Current 25
  Page 1 of 16
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseSP7121340Sp7 transcription factor
img NCI, Score=801, Pubmed Id: 15734992, UMLKSK CUI: C0029463
MouseTBX189096T-box 18
img NCI, Score=801, Pubmed Id: 12663494, UMLKSK CUI: C0029463
MouseTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
img NCI, Score=801, Pubmed Id: 17323424, UMLKSK CUI: C0029463
MouseEZR7430ezrin
img NCI, Score=801, Pubmed Id: 14704791, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 15781656, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 15781656, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 14704791, UMLKSK CUI: C0029463
MouseLOX4015lysyl oxidase
img NCI, Score=801, Pubmed Id: 10841188, UMLKSK CUI: C0029463
MouseIGFBP73490insulin-like growth factor binding protein 7
img NCI, Score=801, Pubmed Id: 10859029, UMLKSK CUI: C0029463
MouseCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
img NCI, Score=801, Pubmed Id: 15584024, UMLKSK CUI: C0029463
MouseBMP4652bone morphogenetic protein 4
img NCI, Score=801, Pubmed Id: 8131348, UMLKSK CUI: C0029463
HumanLOC100507436100507436
img GENERIF, Score=1000, Pubmed Id: 18348660, UMLKSK CUI: C0029463
img GENERIF, Score=1000, Pubmed Id: 18312344, UMLKSK CUI: C0029463
HumanXAGE1B653220X antigen family, member 1B
INFERRED, Score=800, UMLKSK CUI: C0029463
HumanBPY2C442868basic charge, Y-linked, 2C
INFERRED, Score=800, UMLKSK CUI: C0029463
HumanADAMTS19171019ADAM metallopeptidase with thrombospondin type 1 motif, 19
img NCI, Score=801, Pubmed Id: 11867212, UMLKSK CUI: C0029463
HumanZNF384171017zinc finger protein 384
img NCI, Score=801, Pubmed Id: 9581872, UMLKSK CUI: C0029463
HumanHIST4H4121504histone cluster 4, H4
img NCI, Score=801, Pubmed Id: 8485727, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 8366144, UMLKSK CUI: C0029463
HumanSP7121340Sp7 transcription factor
img NCI, Score=801, Pubmed Id: 14604442, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 15734992, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 15734992, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 15734992, UMLKSK CUI: C0029463
HumanEGLN3112399egl-9 family hypoxia-inducible factor 3
img NCI, Score=801, Pubmed Id: 15104534, UMLKSK CUI: C0029463
HumanSARNP84324SAP domain containing ribonucleoprotein
img NCI, Score=801, Pubmed Id: 12633784, UMLKSK CUI: C0029463
img NCI, Score=801, Pubmed Id: 10926290, UMLKSK CUI: C0029463
HumanTBC1D3F84218TBC1 domain family, member 3F
INFERRED, Score=800, UMLKSK CUI: C0029463
HumanLOXL484171lysyl oxidase-like 4
img NCI, Score=801, Pubmed Id: 11691588, UMLKSK CUI: C0029463
HumanBIRC779444baculoviral IAP repeat containing 7
img GENERIF, Score=1000, Pubmed Id: 17632732, UMLKSK CUI: C0029463
HumanRAPH165059Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
img NCI, Score=801, Pubmed Id: 15609301, UMLKSK CUI: C0029463
img GENERIF, Score=1000, Pubmed Id: 15609301, UMLKSK CUI: C0029463
HumanDAZ457135deleted in azoospermia 4
INFERRED, Score=800, UMLKSK CUI: C0029463
HumanZNF39555893zinc finger protein 395
img GENERIF, Score=694, Pubmed Id: 19018758, UMLKSK CUI: C0029463
HumanFBXW755294F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
img GENERIF, Score=1000, Pubmed Id: 16938571, UMLKSK CUI: C0029463
HumanXAF154739XIAP associated factor 1
img NCI, Score=801, Pubmed Id: 16432762, UMLKSK CUI: C0029463
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0029463Osteosarcoma0self