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Details
Link-It Detail - Disease - Mastocytosis
Debug Stats
  • ### Total Build Time: 85 ms 42.979 KB
  • CONCEPT_NAME gt=14 ms Completed: 14 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 300 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 995 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.822 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.090 KB
  • CONCEPT_RELATIONSHIPS gt=45 ms Completed: 45 ms rowSize= 14.676 KB
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 19.455 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Mastocytosis C0024899
Definition (1)
rare disease characterized by an abnormal increase in mast cells in the bone marrow, liver, spleen, lymph nodes, gastrointestinal tract, and skin.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Skin Diseases C0037274
img Neoplasms, Connective Tissue C0027656
Children (4)
img Mastocytoma C2242987
img Mast-Cell Sarcoma C0036221
img Mastocytosis, Cutaneous C1136033
img Mastocytosis, Systemic C0221013
Ancestral Roots
RootRoot Plus OneDepthParent
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372743img Skin Diseases C0037274
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Neoplasms, Connective Tissue C0027656
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097824img Neoplasms, Connective Tissue C0027656
Relationships (49)

Relation Types:
diso_​to_​anat : 18
diso_​to_​chem : 15
diso_​to_​diso : 13
diso_​to_​phen : 3


Relationships:
none : 17
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 4
mapped_​to : 1
may_​treat : 11
permuted_​term_​of : 1
related_​to : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT37img Mast Cells C0024880
DISO_to_PHEN36img genetic aspects C0017399
DISO_to_ANAT35img Mast Cells C0024880
DISO_to_DISO31img Complication Aspects C1171258
DISO_to_PHEN27img genetic aspects C0017399
DISO_to_CHEM24img Proto-Oncogene Protein c-kit C0072470
DISO_to_DISO22img Anaphylaxis C0002792
DISO_to_DISO22img Complication Aspects C1171258
DISO_to_CHEM14img Proto-Oncogene Protein c-kit C0072470
DISO_to_ANAT13img Bone Marrow Cell C0005955
DISO_to_DISO13img CANINE DIS C0012979
DISO_to_CHEM10img Serine Endopeptidases C0036734
DISO_to_ANAT9img In Blood C0005768
DISO_to_CHEM9img TRYPTASE C0147080
DISO_to_ANAT8img Bone Marrow C0005953
DISO_to_ANAT8img In Blood C0005768
DISO_to_DISO8img Cutaneous tumor C0037286
DISO_to_ANATis_associated_anatomic_site_ofimg Bone Marrow C0005953
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Bone Marrow Stem Cell C1511246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Haematopoietic tissue C0229619
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mast Cells C0024880
Genes (95)

Species:
human : 95
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPTPRVP148713protein tyrosine phosphatase, receptor type, V, pseudogene
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanRASGRP4115727RAS guanyl releasing protein 4
img GENERIF, Score=1000, Pubmed Id: 11956218, UMLKSK CUI: C0024899
HumanFIP1L181608factor interacting with PAPOLA and CPSF1
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTPSB264499tryptase beta 2 (gene/pseudogene)
img GENERIF, Score=694, Pubmed Id: 17449330, UMLKSK CUI: C0024899
HumanCTNNBIP156998catenin, beta interacting protein 1
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanCD24451744CD244 molecule, natural killer cell receptor 2B4
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanLRP1229967low density lipoprotein receptor-related protein 12
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanCHIC226511cysteine-rich hydrophobic domain 2
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanMRAS22808muscle RAS oncogene homolog
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanEBAG99166estrogen receptor binding site associated, antigen, 9
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanAIFM19131apoptosis-inducing factor, mitochondrion-associated, 1
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanDLEU28847deleted in lymphocytic leukemia 2 (non-protein coding)
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanIQGAP18826IQ motif containing GTPase activating protein 1
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTNFRSF6B8771tumor necrosis factor receptor superfamily, member 6b, decoy
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanADAM98754ADAM metallopeptidase domain 9
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
img GENERIF, Score=923, Pubmed Id: 16455983, UMLKSK CUI: C0024899
HumanPLA2G68398phospholipase A2, group VI (cytosolic, calcium-independent)
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTPH17166tryptophan hydroxylase 1
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTOC7149tylosis with oesophageal cancer
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTNNI37137troponin I type 3 (cardiac)
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTK17083thymidine kinase 1, soluble
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTIMP17076TIMP metallopeptidase inhibitor 1
INFERRED, Score=800, UMLKSK CUI: C0024899
HumanTERC7012telomerase RNA component
INFERRED, Score=800, UMLKSK CUI: C0024899
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0024899Mastocytosis0self