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Details
Link-It Detail - Disease - Malaria, Falciparum
Debug Stats
  • ### Total Build Time: 106 ms 43.409 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 465 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 543 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 989 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 1.493 KB
  • CONCEPT_RELATIONSHIPS gt=81 ms Completed: 81 ms rowSize= 14.337 KB
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 23.937 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Malaria, Falciparum C0024535
Definition (1)
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Malaria C0024530
Children (2)
img Malaria, Cerebral C0024534
img Blackwater Fever C0005681
Ancestral Roots
RootRoot Plus OneDepthParent
img Parasitic Diseases C0030499img Protozoan Infections C00337404img Malaria C0024530
Relationships (160)

Relation Types:
diso_​to_​anat : 6
diso_​to_​chem : 108
diso_​to_​diso : 32
diso_​to_​gene : 1
diso_​to_​phen : 8
diso_​to_​phys : 5


Relationships:
none : 98
classifies : 1
clinically_​similar : 1
isa : 5
mapped_​to : 3
may_​prevent : 20
may_​treat : 32
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM875img Antimalarials C0003374
DISO_to_CHEM832img 565 ANTIMALARIAL AGENTS C0003374
DISO_to_DISO369img Complication Aspects C1171258
DISO_to_CHEM364img Artemisinins C1136174
DISO_to_CHEM331img Proteins, Protozoan C0033742
DISO_to_DISO329img Complication Aspects C1171258
DISO_to_ANAT324img In Blood C0005768
DISO_to_ANAT319img In Blood C0005768
DISO_to_CHEM254img Antigens, Protozoan C0003338
DISO_to_DISO254img BT - Benign tertian malaria C0024537
DISO_to_CHEM217img Artemisinins C1136174
DISO_to_CHEM207img Malaria Vaccines C0206255
DISO_to_PHEN200img genetic aspects C0017399
DISO_to_CHEM199img 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl- C0008269
DISO_to_CHEM199img Chloroquine C0008269
DISO_to_CHEM182img 2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl- C0034283
DISO_to_CHEM182img Pyrimethamine C0034283
DISO_to_CHEM180img Sesquiterpenes C0036847
DISO_to_CHEM172img Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)- C0038679
DISO_to_CHEM172img Sulfadoxine C0038679
DISO_to_DISO172img BT - Benign tertian malaria C0024537
DISO_to_DISO168img COMPL PARASITIC PREGN C0162494
DISO_to_CHEM167img Antibodies, Protozoan C0003252
DISO_to_CHEM165img Proteins, Protozoan C0033742
DISO_to_PHEN162img Drug Resistance C0013203
Genes (28)

Species:
human : 28
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNCF1653361neutrophil cytosolic factor 1
img GENERIF, Score=1000, Pubmed Id: 19077231, UMLKSK CUI: C0024535
HumanCOL18A180781collagen, type XVIII, alpha 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanIL2159067interleukin 21
img GENERIF, Score=901, Pubmed Id: 18299268, UMLKSK CUI: C0024535
HumanHAVCR126762hepatitis A virus cellular receptor 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanVEGFA7422vascular endothelial growth factor A
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanCX3CL16376chemokine (C-X3-C motif) ligand 1
img GENERIF, Score=1000, Pubmed Id: 14665693, UMLKSK CUI: C0024535
HumanPECAM15175platelet/endothelial cell adhesion molecule 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanNOS24843nitric oxide synthase 2, inducible
img GENERIF, Score=721, Pubmed Id: 15271950, UMLKSK CUI: C0024535
HumanMMP14312matrix metallopeptidase 1 (interstitial collagenase)
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanIL183606interleukin 18 (interferon-gamma-inducing factor)
img GENERIF, Score=1000, Pubmed Id: 12788305, UMLKSK CUI: C0024535
HumanIL12B3593interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanIL103586interleukin 10
img GENERIF, Score=901, Pubmed Id: 15661939, UMLKSK CUI: C0024535
img GENERIF, Score=1000, Pubmed Id: 18972133, UMLKSK CUI: C0024535
HumanIL1RN3557interleukin 1 receptor antagonist
img GENERIF, Score=1000, Pubmed Id: 12472674, UMLKSK CUI: C0024535
HumanIL1B3553interleukin 1, beta
img GENERIF, Score=1000, Pubmed Id: 12472674, UMLKSK CUI: C0024535
HumanIFNGR13459interferon gamma receptor 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanIFNG3458interferon, gamma
img GENERIF, Score=901, Pubmed Id: 15661939, UMLKSK CUI: C0024535
HumanIFNAR13454interferon (alpha, beta and omega) receptor 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanHMOX13162heme oxygenase (decycling) 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanHLA-DRB13123
img GENERIF, Score=901, Pubmed Id: 15728986, UMLKSK CUI: C0024535
HumanHBE13046hemoglobin, epsilon 1
img GENERIF, Score=1000, Pubmed Id: 15114532, UMLKSK CUI: C0024535
HumanGYPB2994glycophorin B (MNS blood group)
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanGYPA2993glycophorin A (MNS blood group)
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanFLT12321fms-related tyrosine kinase 1
INFERRED, Score=800, UMLKSK CUI: C0024535
HumanCYBB1536cytochrome b-245, beta polypeptide
img GENERIF, Score=901, Pubmed Id: 15181570, UMLKSK CUI: C0024535
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0024535Malaria, Falciparum0self