Human | NCF1 | 653361 | neutrophil cytosolic factor 1 | NCF1DeltaGT/GTGT ratios were correlated with clinical parameters and ROI (reactive oxygen intermediates) production during Plasmodium falciparum malaria and with susceptibility to the autoimmune disease multiple sclerosis (MS) |
Human | COL18A1 | 80781 | collagen, type XVIII, alpha 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | IL21 | 59067 | interleukin 21 | Interleukin-21 is associated with IgG1 and IgG3 antibodies to erythrocyte-binding antigen-175 peptide 4 of Plasmodium falciparum in Gabonese children with acute falciparum malaria |
Human | HAVCR1 | 26762 | hepatitis A virus cellular receptor 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | VEGFA | 7422 | vascular endothelial growth factor A | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | TNF | 7124 | tumor necrosis factor | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | CX3CL1 | 6376 | chemokine (C-X3-C motif) ligand 1 | CX3CL1 acts as a receptor for pRBCs, and this may contribute to furthering our present understanding of cytoadherence in the pathology of falciparum malaria |
Human | PECAM1 | 5175 | platelet/endothelial cell adhesion molecule 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | NOS2 | 4843 | nitric oxide synthase 2, inducible | activity in peripheral blood mononuclear cells (PBMCs) is significantly elevated in children with Plasmodium falciparum malarial anemia and inversely associated with hemoglobin levels |
Human | MMP1 | 4312 | matrix metallopeptidase 1 (interstitial collagenase) | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | IL18 | 3606 | interleukin 18 (interferon-gamma-inducing factor) | levels of IL-12 represent a reliable parameter to predict the progression of Plasmodium falciparum malaria, which may be complemented or modulated by IL-18 and TGF-beta |
Human | IL12B | 3593 | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | IL10 | 3586 | interleukin 10 | IL-10 plays a role in regulating T helper 1-type immune responses in neonates born to mothers with placental falciparum malaria at delivery common IL-10 promoter haplotypes condition susceptibility to severe malarial anemia and functional changes in circulating IL-10, TNF-alpha, and IL-12 levels in children with falciparum malaria |
Human | IL1RN | 3557 | interleukin 1 receptor antagonist | Investigation of the possible association of a polymorphism in the interleukin-1 receptor antagonist gene with the severity of Plasmodium falciparum malaria in Ghanaian children |
Human | IL1B | 3553 | interleukin 1, beta | Possible association of a polymorphism in the interleukin-1beta gene with the severity of Plasmodium falciparum malaria in Ghanaian children |
Human | IFNGR1 | 3459 | interferon gamma receptor 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | IFNG | 3458 | interferon, gamma | IFN-gamma plays a role in regulating T helper 1-type immune responses in neonates born to mothers with placental falciparum malaria at delivery |
Human | IFNAR1 | 3454 | interferon (alpha, beta and omega) receptor 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | HMOX1 | 3162 | heme oxygenase (decycling) 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | HLA-DRB1 | 3123 | | A study evaluating the associations between HLA alleles and the severity of malaria in a Thai population, polymorphisms of HLA-B and HLA-DRB1 genes were investigated in 472 adult patients in northwest Thailand with P. falciparum malaria |
Human | HBE1 | 3046 | hemoglobin, epsilon 1 | HbE carrier status has been shown to confer protection against Plasmodium falciparum malaria |
Human | GYPB | 2994 | glycophorin B (MNS blood group) | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | GYPA | 2993 | glycophorin A (MNS blood group) | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | FLT1 | 2321 | fms-related tyrosine kinase 1 | INFERRED, Score=800, UMLKSK CUI: C0024535 |
Human | CYBB | 1536 | cytochrome b-245, beta polypeptide | DNA phasing generated by TA dinucleotide polymorphisms may influence the expression level of gp91 phox of NADPH oxidase and protect against severe falciparum malaria |