Human | ZGLP1 | 100125288 | zinc finger, GATA-like protein 1 | A disturbed GLP-1 secretion does not play a role in blunting the insulin response observed in patients with diabetes and liver cirrhosis |
Human | HSD3B7 | 80270 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | |
Human | RETN | 56729 | resistin | Resistin inhibition may not represent a suitable therapeutic strategy for the treatment of insulin resistance and diabetes in patients with liver cirrhosis |
Human | APOM | 55937 | apolipoprotein M | plasma apoM levels in hepatocellular carcinoma patients were significantly increased than those in the normal subjects, but lower than those in the chronic hepatitis and cirrhosis patients |
Human | UGT1A7 | 54577 | UDP glucuronosyltransferase 1 family, polypeptide A7 | This study demonstrates the novel findings that carriage of low-activity UGT1A7 genotypes represents a risk factor for the development and functional severity of liver cirrhosis Our study shows that UGT1A7 may play a role in hepatocellular carcinogenesis and that this role may differ according to the primary cause of the cirrhosis |
Human | TLR9 | 54106 | toll-like receptor 9 | Title:Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis|Association:Not Found|Conclusion:Our data emphasize the importance of dissecting the innate immune response in PBC. |
Human | GHRL | 51738 | ghrelin/obestatin prepropeptide | In liver cirrhosis, altered postprandial glucose and ghrelin are associated with reduced energy intake and weight loss |
Human | GMNN | 51053 | geminin, DNA replication inhibitor | The combination of MCM2, geminin and Ki67 could represent a valuable tool in the understanding of hepatocellular carcinoma progression in cirrhosis |
Human | SLC40A1 | 30061 | solute carrier family 40 (iron-regulated transporter), member 1 | the presence of cirrhosis is an independent factor associated with increased expression of DMT1 but not Ireg1 |
Human | BSCL2 | 26580 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | |
Human | TINF2 | 26277 | TERF1 (TRF1)-interacting nuclear factor 2 | |
Human | RASSF1 | 11186 | Ras association (RalGDS/AF-6) domain family member 1 | The significant difference in methylation of RASSF1A observed in the liver neoplasms and liver cirrhosis was not observed in the plasma samples |
Human | ADAMTS13 | 11093 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 | An imbalance between the decreased ADAMTS13:AC and its increased substrate may reflect the predisposing state for platelet thrombi formation in patients with advanced liver cirrhosis Inhibited in the blood of a paatient with hepatitis C virus-related liver cirrhosis causes thrombotic thrombocytopenic purpura |
Human | AGPAT2 | 10555 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | |
Human | PROCR | 10544 | protein C receptor, endothelial | possible role for high levels of thrombomodulin as a marker of HCC development in patients with cirrhosis, whereas high levels of EPCR are a possible marker of worse HCC prognosis, being a sign of endothelial damage of large vessels |
Human | PIAS3 | 10401 | protein inhibitor of activated STAT, 3 | INFERRED, Score=800, UMLKSK CUI: C0023890 |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | These results demonstrate that 1) adiponectin plasma levels in cirrhosis are significantly elevated, 2) the liver is a major source of adiponectin extraction, and 3) adiponectin levels in cirrhosis do not correlate with parameters of body composition |
Human | FIBP | 9158 | fibroblast growth factor (acidic) intracellular binding protein | Data Show aFGF was expressed in regenerative hepatocytes, but not in fibroblasts, suggesting its role in promoting oxidative stress produced by hepatocytes may contribute to the development of fibrous bands in hepatic cirrhosis |
Human | APLN | 8862 | apelin | Human patients with liver cirrhosis show a marked increase in apelin levels |
Human | NR1I2 | 8856 | nuclear receptor subfamily 1, group I, member 2 | Title:Genetic polymorphisms influencing xenobiotic metabolism and transport in patients with primary biliary cirrhosis|Association:Not Found|Conclusion:In conclusion, genetic polymorphisms of CYP 2D6 and 2E1, PXR, and MDR1 do not appear to play a role in the onset of PBC. |
Human | ABCB11 | 8647 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | |
Human | WT1 | 7490 | Wilms tumor 1 | WT1 is reexpressed in the cirrhotic liver in relation to disease progression and may play a role in the development of hepatic insufficiency in cirrhosis |
Human | WEE1 | 7465 | WEE1 homolog (S. pombe) | increases of cyclin D1, cyclin-dependent kinase 4, cyclin E, cyclin A, and Wee1 play an important role in the development of hepatocellular carcinoma from cirrhosis |
Human | VIPR1 | 7433 | vasoactive intestinal peptide receptor 1 | Genetic complexity of HVR1 quasispecies of hepatitis C virus in patients with cirrhosis |
Human | VEGFA | 7422 | vascular endothelial growth factor A | VEGF may play an important role in the angiogenesis and prognosis of hepatocellular carcinoma, as well as in the angiogenesis of liver cirrhosis Plasma VEGF and bFGF are elevated in patients with liver cirrhosis, depending on age and are predictors of outcome VEGF and sVEGF-R1 were increased respectively to the degree of liver insufficiency in patients with liver cirrhosis the protein level of VEGF can reflect the compensation status of cirrhosis patients and may act as an anti-cirrhotic factor |