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Details
Link-It Detail - Disease - Leukoplakia, Oral
Debug Stats
  • ### Total Build Time: 171 ms 46.324 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 502 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=8 ms Completed: 8 ms rowSize= 980 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 556 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=12 ms Completed: 12 ms rowSize= 5.314 KB
  • CONCEPT_RELATIONSHIPS gt=100 ms Completed: 100 ms rowSize= 12.893 KB
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 24.441 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukoplakia, Oral C0023532
Definition (1)
A white patch or plaque on oral mucosa that cannot be characterized clinically or pathologically as any other disease. The diagnosis of leukoplakia is one of exclusion; other conditions such as candidiasis, lichen planus, leukoedema, etc. must be ruled out before a diagnosis of leukoplakia can be made. Leukoplakia may be a premalignant condition.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Mouth Neoplasms C0026640
img Leukoplakia C0023531
Children (1)
img Leukoplakia, Hairy C0206186
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Site C00276535img Mouth Neoplasms C0026640
img Stomatognathic Diseases C0038368img Mouth Diseases C00266364img Mouth Neoplasms C0026640
img Pathological Conditions, Signs and Symptoms C0039058img Pathological Conditions, Anatomical C07521354img Leukoplakia C0023531
img Neoplasms C0027651img Precancerous Conditions C00329274img Leukoplakia C0023531
Relationships (44)

Relation Types:
diso_​to_​anat : 5
diso_​to_​chem : 4
diso_​to_​diso : 33
diso_​to_​phen : 2


Relationships:
none : 23
associated_​with : 1
is_​associated_​anatomic_​site_​of : 2
isa : 15
location_​of : 1
mapped_​to : 2
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO124img Mouth Neoplasms C0026640
DISO_to_DISO86img Carcinoma, Squamous Cell C0007137
DISO_to_DISO64img Mouth Neoplasms C0026640
DISO_to_DISO52img Precancerous Conditions C0032927
DISO_to_PHEN48img genetic aspects C0017399
DISO_to_DISO41img Carcinoma, Squamous Cell C0007137
DISO_to_ANAT36img Mouth Mucosa C0026639
DISO_to_DISO31img Precancerous Conditions C0032927
DISO_to_PHEN30img genetic aspects C0017399
DISO_to_ANAT18img Mouth Mucosa C0026639
DISO_to_CHEM15img Tumor Markers, Biological C0041366
DISO_to_DISO12img Carcinoma, Verrucous C0206706
DISO_to_DISO12img Cell Transformation, Neoplastic C0007621
DISO_to_DISO12img Erythroplasia C0014818
DISO_to_DISO12img Lichen Planus, Oral C0206139
DISO_to_DISO11img NEOPL TONGUE C0040411
DISO_to_CHEM10img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO10img Complication Aspects C1171258
DISO_to_CHEM9img Protein p53 C0080055
DISO_to_CHEM8img Protein p53 C0080055
DISO_to_DISO8img CELL TRANSFORM NEOPL C0007621
DISO_to_DISO8img Complication Aspects C1171258
DISO_to_DISO8img GINGIVAL NEOPL C0017570
DISO_to_ANATlocation_ofimg Buccal mucosa C1578559
DISO_to_ANATis_associated_anatomic_site_ofimg Head and neck structure C0460004
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanMERTK10461c-mer proto-oncogene tyrosine kinase
INFERRED, Score=800, UMLKSK CUI: C0023532
HumanPDCD59141programmed cell death 5
img NCI, Score=801, Pubmed Id: 16086069, UMLKSK CUI: C0023532
img NCI, Score=801, Pubmed Id: 16086069, UMLKSK CUI: C0023532
HumanTP638626tumor protein p63
img NCI, Score=801, Pubmed Id: 15655576, UMLKSK CUI: C0023532
HumanSDC16382syndecan 1
img NCI, Score=801, Pubmed Id: 12969225, UMLKSK CUI: C0023532
img NCI, Score=801, Pubmed Id: 12969225, UMLKSK CUI: C0023532
img NCI, Score=801, Pubmed Id: 12969225, UMLKSK CUI: C0023532
HumanKLK75650kallikrein-related peptidase 7
img NCI, Score=801, Pubmed Id: 8800294, UMLKSK CUI: C0023532
HumanKRT173872keratin 17
img OMIM, Score=1000, UMLKSK CUI: C0023532
HumanKRT133860keratin 13
img NCI, Score=801, Pubmed Id: 8634660, UMLKSK CUI: C0023532
HumanKRT6B3854keratin 6B
img OMIM, Score=1000, UMLKSK CUI: C0023532
HumanKRT13848keratin 1
img NCI, Score=801, Pubmed Id: 8634660, UMLKSK CUI: C0023532
HumanIVL3713involucrin
img NCI, Score=801, Pubmed Id: 2479742, UMLKSK CUI: C0023532
img NCI, Score=801, Pubmed Id: 8634660, UMLKSK CUI: C0023532
HumanITGA93680integrin, alpha 9
img NCI, Score=801, Pubmed Id: 10483066, UMLKSK CUI: C0023532
HumanGSTM32947glutathione S-transferase mu 3 (brain)
img NCI, Score=801, Pubmed Id: 16172217, UMLKSK CUI: C0023532
img NCI, Score=801, Pubmed Id: 16172217, UMLKSK CUI: C0023532
HumanGSTM12944glutathione S-transferase mu 1
img GENERIF, Score=1000, Pubmed Id: 16519766, UMLKSK CUI: C0023532
HumanGJB22706gap junction protein, beta 2, 26kDa
img OMIM, Score=1000, UMLKSK CUI: C0023532
HumanDFFA1676DNA fragmentation factor, 45kDa, alpha polypeptide
img NCI, Score=801, Pubmed Id: 11846001, UMLKSK CUI: C0023532
HumanDBC11620
img NCI, Score=801, Pubmed Id: 15226771, UMLKSK CUI: C0023532
HumanCDKN1B1027cyclin-dependent kinase inhibitor 1B (p27, Kip1)
img GENERIF, Score=1000, Pubmed Id: 12820381, UMLKSK CUI: C0023532
HumanBMP6654bone morphogenetic protein 6
INFERRED, Score=800, UMLKSK CUI: C0023532
HumanATM472ataxia telangiectasia mutated
img GENERIF, Score=1000, Pubmed Id: 18288488, UMLKSK CUI: C0023532
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023532Leukoplakia, Oral0self