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Details
Link-It Detail - Disease - Leukemia, Prolymphocytic
Debug Stats
  • ### Total Build Time: 156 ms 48.022 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 399 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 333 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=16 ms Completed: 16 ms rowSize= 554 bytes
  • CONCEPT_CHILDREN gt=12 ms Completed: 12 ms rowSize= 1,020 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 4.063 KB
  • CONCEPT_RELATIONSHIPS gt=78 ms Completed: 78 ms rowSize= 15.010 KB
  • CONCEPT_GENES gt=36 ms Completed: 36 ms rowSize= 25.329 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.158 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukemia, Prolymphocytic C0023486
Prolymphocytic Leukemia
Definition (1)
A chronic leukemia characterized by a large number of circulating prolymphocytes. It can arise spontaneously or as a consequence of transformation of CHRONIC LYMPHOCYTIC LEUKEMIA.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, Lymphoid C0023448
Children (2)
img Leukemia, Prolymphocytic, B-Cell C0475801
img Leukemia, Prolymphocytic, T-Cell C2363142
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Leukemia, Lymphoid C0023448
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210705img Leukemia, Lymphoid C0023448
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242285img Leukemia, Lymphoid C0023448
Relationships (41)

Relation Types:
diso_​to_​anat : 17
diso_​to_​chem : 3
diso_​to_​diso : 19
diso_​to_​phen : 2


Relationships:
none : 14
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 4
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​finding_​of_​disease : 2
replaces : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO27img Leukemia, T-Cell C0023492
DISO_to_PHEN24img genetic aspects C0017399
DISO_to_DISO12img Chronic Lymphocytic Leukemia C0023434
DISO_to_PHEN12img genetic aspects C0017399
DISO_to_ANAT7img In Blood C0005768
DISO_to_CHEM7img Antibodies, Monoclonal C0003250
DISO_to_DISO7img Chronic Lymphocytic Leukemia C0023434
DISO_to_DISO7img Complication Aspects C1171258
DISO_to_CHEM6img ANTIBODIES NEOPL C0003251
DISO_to_CHEM6img Antineoplastic Agents C0003392
DISO_to_DISO6img Chromosomal translocation C0040715
DISO_to_DISO6img Leukemia, B-Cell C2004493
DISO_to_DISO6img Leukemia, Prolymphocytic, T-Cell C2363142
DISO_to_DISO6img Lymphoma, Mantle-Cell C0334634
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Bone Marrow C0005953
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_associated_anatomic_site_ofimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Cell C1517806
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Lymphocyte C1517808
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Lymphatic System C0024235
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lymphoid Tissue C0024296
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mature Lymphocyte C1513026
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanBCL108915B-cell CLL/lymphoma 10
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanIFITM18519interferon induced transmembrane protein 1
img NCI, Score=801, Pubmed Id: 2265250, UMLKSK CUI: C0023486
HumanTCL1A8115T-cell leukemia/lymphoma 1A
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanD13S258101Disrupted in B-cell neoplasia
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanZAP707535zeta-chain (TCR) associated protein kinase 70kDa
img GENERIF, Score=901, Pubmed Id: 16642047, UMLKSK CUI: C0023486
HumanTRA@6955
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanTAL16886T-cell acute lymphocytic leukemia 1
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanSELL6402selectin L
img NCI, Score=801, Pubmed Id: 11172297, UMLKSK CUI: C0023486
HumanRAB1A5861RAB1A, member RAS oncogene family
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanABCB45244ATP-binding cassette, sub-family B (MDR/TAP), member 4
img NCI, Score=801, Pubmed Id: 2323839, UMLKSK CUI: C0023486
img NCI, Score=801, Pubmed Id: 2323839, UMLKSK CUI: C0023486
HumanMYBL14603v-myb avian myeloblastosis viral oncogene homolog-like 1
img NCI, Score=801, Pubmed Id: 8634438, UMLKSK CUI: C0023486
HumanMTCP14515mature T-cell proliferation 1
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanITGB23689integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanITGAL3683integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanHEXB3074hexosaminidase B (beta polypeptide)
img NCI, Score=801, Pubmed Id: 6982610, UMLKSK CUI: C0023486
HumanFMOD2331fibromodulin
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanFCER22208Fc fragment of IgE, low affinity II, receptor for (CD23)
img NCI, Score=801, Pubmed Id: 11920534, UMLKSK CUI: C0023486
img NCI, Score=801, Pubmed Id: 10911380, UMLKSK CUI: C0023486
HumanCSF2RA1438colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
img NCI, Score=801, Pubmed Id: 8695795, UMLKSK CUI: C0023486
HumanCD38952CD38 molecule
img NCI, Score=801, Pubmed Id: 2194392, UMLKSK CUI: C0023486
img GENERIF, Score=901, Pubmed Id: 16642047, UMLKSK CUI: C0023486
HumanCD33945CD33 molecule
img NCI, Score=801, Pubmed Id: 15854271, UMLKSK CUI: C0023486
HumanTNFSF8944tumor necrosis factor (ligand) superfamily, member 8
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanCD22933CD22 molecule
img NCI, Score=801, Pubmed Id: 10911380, UMLKSK CUI: C0023486
HumanMS4A1931membrane-spanning 4-domains, subfamily A, member 1
img NCI, Score=801, Pubmed Id: 11669307, UMLKSK CUI: C0023486
HumanATM472ataxia telangiectasia mutated
INFERRED, Score=800, UMLKSK CUI: C0023486
HumanIL14~withdrawn0
img NCI, Score=801, Pubmed Id: 2681271, UMLKSK CUI: C0023486
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023486Leukemia, Prolymphocytic0self