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Details
Link-It Detail - Disease - Leukemia, Myelomonocytic, Chronic
Debug Stats
  • ### Total Build Time: 254 ms 71.970 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 398 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 415 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 1,014 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=11 ms Completed: 11 ms rowSize= 2.806 KB
  • CONCEPT_RELATIONSHIPS gt=178 ms Completed: 178 ms rowSize= 16.561 KB
  • CONCEPT_GENES gt=37 ms Completed: 37 ms rowSize= 49.435 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukemia, Myelomonocytic, Chronic C0023480
CMML
Definition (1)
A slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a type of white blood cell) are in the bone marrow, crowding out other normal blood cells, such as other white blood cells, red blood cells, and platelets.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Leukemia, Myeloid C0023470
img Myelodysplastic-Myeloproliferative Diseases C1301355
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Leukemia, Myeloid C0023470
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189395img Myelodysplastic-Myeloproliferative Diseases C1301355
Relationships (74)

Relation Types:
diso_​to_​anat : 18
diso_​to_​chem : 10
diso_​to_​diso : 36
diso_​to_​gene : 2
diso_​to_​phen : 6
diso_​to_​phys : 2


Relationships:
none : 26
expanded_​form_​of : 1
gene_​associated_​with_​disease : 2
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 5
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​cytogenetic_​abnormality_​of_​disease : 2
is_​not_​molecular_​abnormality_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 3
may_​be_​abnormal_​cell_​of_​disease : 6
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 3
may_​be_​finding_​of_​disease : 12
may_​be_​molecular_​abnormality_​of_​disease : 1
related_​to : 1
Page Size
Current 25
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Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN72img genetic aspects C0017399
DISO_to_PHEN47img genetic aspects C0017399
DISO_to_DISO42img Complication Aspects C1171258
DISO_to_DISO32img Complication Aspects C1171258
DISO_to_DISO29img Myelodysplastic Syndromes C0026986
DISO_to_PHYS26img Mutation C0026882
DISO_to_CHEM18img Azacitidine C0004475
DISO_to_DISO18img Dysmyelopoietic Syndromes C0026986
DISO_to_DISO18img Leukemia, Myelocytic, Acute C0023467
DISO_to_CHEM15img Binding Protein, DNA C0012940
DISO_to_CHEM15img DNA-Binding Proteins C0012940
DISO_to_CHEM14img Antimetabolites, Antineoplastic C0003377
DISO_to_CHEM14img Cellular Proto Oncogene Proteins C0033712
DISO_to_CHEM14img Proto-Oncogene Proteins C0033712
DISO_to_DISO11img Myeloproliferative Disorders C0027022
DISO_to_ANAT10img In Blood C0005768
DISO_to_DISO10img Leukemia, Myelomonocytic, Acute C0023479
DISO_to_DISO9img Myeloproliferative Disorders C0027022
DISO_to_ANAT8img In Blood C0005768
DISO_to_CHEM8img Antineoplastic Agents C0003392
DISO_to_CHEM8img Piperazines C0031958
DISO_to_CHEM8img Pyrimidines C0034289
DISO_to_DISO8img Leukemia, Myelocytic, Acute C0023467
DISO_to_DISO8img Leukemic Infiltration C0162679
DISO_to_CHEM7img BIOCHEM TUMOR MARKERS C0041366
Genes (33)

Species:
human : 32
mouse : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseHIP13092huntingtin interacting protein 1
img NCI, Score=801, Pubmed Id: 11604514, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 11287412, UMLKSK CUI: C0023480
HumanMVP9961major vault protein
img NCI, Score=801, Pubmed Id: 12801535, UMLKSK CUI: C0023480
HumanCD1639332CD163 molecule
img NCI, Score=801, Pubmed Id: 15491976, UMLKSK CUI: C0023480
HumanIL329235interleukin 32
img GENERIF, Score=1000, Pubmed Id: 18287021, UMLKSK CUI: C0023480
HumanRABEP19135rabaptin, RAB GTPase binding effector protein 1
img NCI, Score=801, Pubmed Id: 11588050, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 12130532, UMLKSK CUI: C0023480
HumanSPN6693sialophorin
img NCI, Score=801, Pubmed Id: 10834507, UMLKSK CUI: C0023480
HumanPTPN115781protein tyrosine phosphatase, non-receptor type 11
img NCI, Score=801, Pubmed Id: 15725481, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 15725481, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 15725481, UMLKSK CUI: C0023480
img GENERIF, Score=1000, Pubmed Id: 15725481, UMLKSK CUI: C0023480
HumanPROS15627protein S (alpha)
img NCI, Score=801, Pubmed Id: 12923583, UMLKSK CUI: C0023480
HumanSERPINB105273serpin peptidase inhibitor, clade B (ovalbumin), member 10
img NCI, Score=801, Pubmed Id: 9454755, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 10871600, UMLKSK CUI: C0023480
HumanPDGFRB5159platelet-derived growth factor receptor, beta polypeptide
img NCI, Score=801, Pubmed Id: 12908555, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 9057655, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 9009269, UMLKSK CUI: C0023480
img GENERIF, Score=923, Pubmed Id: 17301821, UMLKSK CUI: C0023480
HumanPDGFB5155platelet-derived growth factor beta polypeptide
img NCI, Score=801, Pubmed Id: 3456250, UMLKSK CUI: C0023480
HumanNUP984928nucleoporin 98kDa
img NCI, Score=801, Pubmed Id: 10565304, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 10565304, UMLKSK CUI: C0023480
HumanMPL4352myeloproliferative leukemia virus oncogene
img NCI, Score=801, Pubmed Id: 7773160, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 9031083, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 7773160, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 7539513, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 8751457, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 7539513, UMLKSK CUI: C0023480
HumanMLL4297
img GENERIF, Score=923, Pubmed Id: 17280715, UMLKSK CUI: C0023480
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
img NCI, Score=801, Pubmed Id: 12393641, UMLKSK CUI: C0023480
HumanKDR3791kinase insert domain receptor (a type III receptor tyrosine kinase)
img NCI, Score=801, Pubmed Id: 11222390, UMLKSK CUI: C0023480
HumanJAK23717Janus kinase 2
img GENERIF, Score=1000, Pubmed Id: 17151700, UMLKSK CUI: C0023480
HumanHOXA93205homeobox A9
img NCI, Score=801, Pubmed Id: 10565304, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 10565304, UMLKSK CUI: C0023480
HumanHIP13092huntingtin interacting protein 1
img NCI, Score=801, Pubmed Id: 9616134, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 10428802, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 9616134, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 12681968, UMLKSK CUI: C0023480
HumanFRA16B2461fragile site, distamycin A type, rare, fra(16)(q22.1)
img NCI, Score=801, Pubmed Id: 2208058, UMLKSK CUI: C0023480
HumanFLT12321fms-related tyrosine kinase 1
img NCI, Score=801, Pubmed Id: 11222390, UMLKSK CUI: C0023480
HumanF112160coagulation factor XI
img NCI, Score=801, Pubmed Id: 11685043, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 11442650, UMLKSK CUI: C0023480
HumanCSF1R1436colony stimulating factor 1 receptor
img NCI, Score=801, Pubmed Id: 8426743, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 2406720, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 8494999, UMLKSK CUI: C0023480
img NCI, Score=801, Pubmed Id: 1613006, UMLKSK CUI: C0023480
HumanCD38952CD38 molecule
img NCI, Score=801, Pubmed Id: 12239142, UMLKSK CUI: C0023480
HumanCD36948CD36 molecule (thrombospondin receptor)
img NCI, Score=801, Pubmed Id: 12239142, UMLKSK CUI: C0023480
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023480Leukemia, Myelomonocytic, Chronic0self