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Details
Link-It Detail - Disease - Leukemia, Myeloid, Chronic-Phase
Debug Stats
  • ### Total Build Time: 224 ms 33.342 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 452 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=16 ms Completed: 16 ms rowSize= 584 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=31 ms Completed: 31 ms rowSize= 2.841 KB
  • CONCEPT_RELATIONSHIPS gt=146 ms Completed: 146 ms rowSize= 16.445 KB
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 11.260 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukemia, Myeloid, Chronic-Phase C0023474
CGL, chronic phase
Definition (1)
The initial phase of chronic myeloid leukemia consisting of an relatively indolent period lasting from 4 to 7 years. Patients range from asymptomatic to those exhibiting ANEMIA; SPLENOMEGALY; and increased cell turnover. There are 5% or fewer blast cells in the blood and bone marrow in this phase.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
Ancestral Roots
RootRoot Plus OneDepthParent
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189396img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
Relationships (56)

Relation Types:
diso_​to_​anat : 17
diso_​to_​chem : 9
diso_​to_​diso : 27
diso_​to_​phen : 3


Relationships:
none : 11
clinically_​similar : 1
entry_​version_​of : 1
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 8
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 3
is_​not_​molecular_​abnormality_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
may_​be_​abnormal_​cell_​of_​disease : 2
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 2
may_​be_​finding_​of_​disease : 6
may_​be_​molecular_​abnormality_​of_​disease : 3
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM120img Pyrimidines C0034289
DISO_to_CHEM105img Piperazines C0031958
DISO_to_PHEN65img genetic aspects C0017399
DISO_to_CHEM57img Antineoplastic Agents C0003392
DISO_to_CHEM48img Protein Kinase Inhibitors C1449702
DISO_to_CHEM40img Pyrimidines C0034289
DISO_to_CHEM39img Piperazines C0031958
DISO_to_CHEM32img Antineoplastic Agents C0003392
DISO_to_CHEM28img Thiazoles C0039859
DISO_to_CHEM26img Fusion Proteins, bcr-abl C0004891
DISO_to_DISO25img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg 'Sea blue' histiocytes C0333836
DISO_to_ANATis_associated_anatomic_site_ofimg Bone Marrow C0005953
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Bone Marrow Stem Cell C1511246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Haematopoietic tissue C0229619
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_abnormal_cell_of_diseaseimg Hypolobated Megakaryocyte C1512565
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Cell C1517806
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Myeloid Cell C1514039
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanLHX29355LIM homeobox 2
img NCI, Score=801, Pubmed Id: 8683990, UMLKSK CUI: C0023474
HumanSQSTM18878sequestosome 1
img NCI, Score=801, Pubmed Id: 8637231, UMLKSK CUI: C0023474
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 11877311, UMLKSK CUI: C0023474
HumanTIE17075tyrosine kinase with immunoglobulin-like and EGF-like domains 1
img NCI, Score=801, Pubmed Id: 11920509, UMLKSK CUI: C0023474
img GENERIF, Score=923, Pubmed Id: 11920509, UMLKSK CUI: C0023474
img NCI, Score=801, Pubmed Id: 11920509, UMLKSK CUI: C0023474
img NCI, Score=801, Pubmed Id: 11920509, UMLKSK CUI: C0023474
HumanMPL4352myeloproliferative leukemia virus oncogene
img NCI, Score=801, Pubmed Id: 10649249, UMLKSK CUI: C0023474
HumanIL33562interleukin 3 (colony-stimulating factor, multiple)
img NCI, Score=801, Pubmed Id: 9529127, UMLKSK CUI: C0023474
img NCI, Score=801, Pubmed Id: 11222392, UMLKSK CUI: C0023474
HumanESR12099estrogen receptor 1
img NCI, Score=801, Pubmed Id: 8640788, UMLKSK CUI: C0023474
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023474Leukemia, Myeloid, Chronic-Phase0self