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Details
Link-It Detail - Disease - Leukemia, Monocytic, Acute
Debug Stats
  • ### Total Build Time: 211 ms 34.728 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 366 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=8 ms Completed: 8 ms rowSize= 560 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.509 KB
  • CONCEPT_RELATIONSHIPS gt=153 ms Completed: 153 ms rowSize= 16.049 KB
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 14.546 KB
  • CONCEPT_XREFS gt=10 ms Completed: 10 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukemia, Monocytic, Acute C0023465
Definition (1)
Acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage. Bleeding disorders are common presenting features. It usually follows an aggressive clinical course. (WHO, 2001) -- 2003
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, Myeloid, Acute C0023467
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, Myeloid, Acute C0023467
Relationships (72)

Relation Types:
diso_​to_​anat : 22
diso_​to_​chem : 14
diso_​to_​diso : 28
diso_​to_​gene : 1
diso_​to_​phen : 4
diso_​to_​phys : 3


Relationships:
none : 38
associated_​with : 2
classifies : 1
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 8
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 4
mapped_​to : 1
may_​be_​finding_​of_​disease : 2
use : 2
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN61img genetic aspects C0017399
DISO_to_PHEN52img genetic aspects C0017399
DISO_to_DISO22img Chromosomal translocation C0040715
DISO_to_DISO21img Complication Aspects C1171258
DISO_to_DISO20img Complication Aspects C1171258
DISO_to_DISO17img Chromosomal translocation C0040715
DISO_to_CHEM16img Oncogene Proteins, Fusion C0029014
DISO_to_ANAT15img Chromosome 11 C0008653
DISO_to_CHEM12img TRANSCRIPTION FACTOR C0040648
DISO_to_CHEM12img Transcription Factors C0040648
DISO_to_CHEM11img Binding Protein, DNA C0012940
DISO_to_CHEM11img DNA-Binding Proteins C0012940
DISO_to_DISO11img Leukemia, Myelocytic, Acute C0023467
DISO_to_DISO11img Leukemia, Myelomonocytic, Acute C0023479
DISO_to_DISO10img METACHRONOUS NEOPL C0085183
DISO_to_GENE10img Cellular Oncogene C0033713
DISO_to_DISO9img Infiltration, Leukemic C0162679
DISO_to_PHYS9img Apoptosis C0162638
DISO_to_ANAT8img Chromosomes, Human, Pair 8 C0008671
DISO_to_ANAT8img Skin C1123023
DISO_to_CHEM8img Acute Lymphoblastic Leukemia Protein 1 C1571619
DISO_to_CHEM8img Myeloid-Lymphoid Leukemia Protein C1571619
DISO_to_DISO8img Precursor Cell Lymphoblastic Leukemia-Lymphoma C1961102
DISO_to_ANAT7img Monocytes C0026473
DISO_to_CHEM7img Antineoplastic Agents C0003392
Genes (14)

Species:
human : 14
SpeciesGeneGeneIdGene NameEvidence
HumanCD27429126CD274 molecule
img GENERIF, Score=976, Pubmed Id: 18756622, UMLKSK CUI: C0023465
HumanABI110006abl-interactor 1
img GENERIF, Score=923, Pubmed Id: 12547160, UMLKSK CUI: C0023465
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img GENERIF, Score=756, Pubmed Id: 15145445, UMLKSK CUI: C0023465
HumanSPI16688spleen focus forming virus (SFFV) proviral integration oncogene
img GENERIF, Score=983, Pubmed Id: 18308386, UMLKSK CUI: C0023465
HumanSH3GL16455SH3-domain GRB2-like 1
img NCI, Score=801, Pubmed Id: 15077184, UMLKSK CUI: C0023465
HumanMLL4297
img GENERIF, Score=923, Pubmed Id: 12547160, UMLKSK CUI: C0023465
HumanIL83576interleukin 8
img GENERIF, Score=1000, Pubmed Id: 17914409, UMLKSK CUI: C0023465
HumanGFI12672growth factor independent 1 transcription repressor
img OMIM, Score=1000, UMLKSK CUI: C0023465
HumanELANE1991elastase, neutrophil expressed
img OMIM, Score=1000, UMLKSK CUI: C0023465
HumanCSF21437colony stimulating factor 2 (granulocyte-macrophage)
img GENERIF, Score=1000, Pubmed Id: 17914409, UMLKSK CUI: C0023465
HumanCSF1R1436colony stimulating factor 1 receptor
img GENERIF, Score=1000, Pubmed Id: 14738146, UMLKSK CUI: C0023465
HumanCD44960CD44 molecule (Indian blood group)
img GENERIF, Score=1000, Pubmed Id: 17914409, UMLKSK CUI: C0023465
HumanCBL867Cbl proto-oncogene, E3 ubiquitin protein ligase
img GENERIF, Score=1000, Pubmed Id: 14738146, UMLKSK CUI: C0023465
HumanRUNX1861runt-related transcription factor 1
img OMIM, Score=1000, UMLKSK CUI: C0023465
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023465Leukemia, Monocytic, Acute0self