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Details
Link-It Detail - Disease - Leukemia, Lymphocytic, Chronic, B-Cell
Debug Stats
  • ### Total Build Time: 783 ms 67.412 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 374 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 432 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=8 ms Completed: 8 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 4.058 KB
  • CONCEPT_RELATIONSHIPS gt=578 ms Completed: 578 ms rowSize= 17.982 KB
  • CONCEPT_GENES gt=176 ms Completed: 176 ms rowSize= 42.656 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukemia, Lymphocytic, Chronic, B-Cell C0023434
Definition (1)
An indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly in the blood and bone marrow. Sometimes, in later stages of the disease, cancer cells are found in the lymph nodes and the disease is called small lymphocytic lymphoma.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, B-Cell C2004493
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, B-Cell C2004493
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Leukemia, B-Cell C2004493
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Leukemia, B-Cell C2004493
Relationships (277)

Relation Types:
diso_​to_​anat : 37
diso_​to_​chem : 104
diso_​to_​diso : 85
diso_​to_​gene : 34
diso_​to_​phen : 2
diso_​to_​phys : 15


Relationships:
none : 150
associated_​with : 2
clinically_​similar : 2
disease_​has_​associated_​disease : 2
gene_​associated_​with_​disease : 30
gene_​product_​malfunction_​associated_​with_​disease : 2
inheritance_​type_​of : 1
is_​abnormal_​cell_​of_​disease : 9
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 4
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 22
manifestation_​of : 3
mapped_​to : 1
may_​be_​finding_​of_​disease : 2
may_​treat : 31
permuted_​term_​of : 1
related_​to : 5
Page Size
Current 25
  Page 1 of 12
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN989img genetic aspects C0017399
DISO_to_PHEN589img genetic aspects C0017399
DISO_to_DISO308img Complication Aspects C1171258
DISO_to_CHEM304img Antineoplastic Agents C0003392
DISO_to_DISO293img Complication Aspects C1171258
DISO_to_CHEM228img Antineoplastic Agents C0003392
DISO_to_ANAT216img In Blood C0005768
DISO_to_CHEM207img Antibodies, Monoclonal C0003250
DISO_to_CHEM184img Antibodies, Monoclonal C0003250
DISO_to_ANAT175img B-Lymphocytes C0004561
DISO_to_CHEM172img 9 beta Arabinofuranosyladenine C0042646
DISO_to_CHEM172img Vidarabine C0042646
DISO_to_PHYS144img Apoptosis C0162638
DISO_to_PHYS143img Apoptosis C0162638
DISO_to_ANAT136img In Blood C0005768
DISO_to_ANAT120img B-Lymphocytes C0004561
DISO_to_CHEM117img Tumor Markers, Biological C0041366
DISO_to_CHEM90img ANTIBODIES NEOPL C0003251
DISO_to_CHEM90img Antibodies, Neoplasm C0003251
DISO_to_CHEM85img 9 beta Arabinofuranosyladenine C0042646
DISO_to_PHYS84img Mutation C0026882
DISO_to_CHEM82img ZAP-70 Kinase C0246976
DISO_to_CHEM77img HEAVY CHAIN IG C0021034
DISO_to_CHEM77img Immunoglobulin Heavy Chains C0021034
DISO_to_CHEM75img Antigens, CD C0003322
Genes (291)

Species:
human : 288
mouse : 3
Page Size
Current 25
  Page 1 of 12
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseBCL2L1110018BCL2-like 11 (apoptosis facilitator)
img NCI, Score=801, Pubmed Id: 15079075, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 15079075, UMLKSK CUI: C0023434
MouseIL33562interleukin 3 (colony-stimulating factor, multiple)
img NCI, Score=801, Pubmed Id: 8906104, UMLKSK CUI: C0023434
MouseCD22933CD22 molecule
img NCI, Score=801, Pubmed Id: 15897589, UMLKSK CUI: C0023434
HumanGGT2728441gamma-glutamyltransferase 2
img NCI, Score=801, Pubmed Id: 24319, UMLKSK CUI: C0023434
HumanCLLU1574028chronic lymphocytic leukemia up-regulated 1
Click here to display 12 evidence detail records.
HumanMIR181B2406956microRNA 181b-2
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
HumanMIR181B1406955microRNA 181b-1
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
HumanMIR181A2406954microRNA 181a-2
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
HumanMIR16-2406951
img NCI, Score=801, Pubmed Id: 15737576, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 15737576, UMLKSK CUI: C0023434
HumanMIR16-1406950
Click here to display 7 evidence detail records.
HumanMIR142406934microRNA 142
img NCI, Score=801, Pubmed Id: 15737576, UMLKSK CUI: C0023434
HumanKCNRG283518potassium channel regulator
img NCI, Score=801, Pubmed Id: 12650944, UMLKSK CUI: C0023434
HumanDLEU7220107deleted in lymphocytic leukemia, 7
img NCI, Score=801, Pubmed Id: 14706829, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 14706829, UMLKSK CUI: C0023434
HumanARHGAP27201176Rho GTPase activating protein 27
img NCI, Score=801, Pubmed Id: 15492870, UMLKSK CUI: C0023434
HumanFAM129C199786family with sequence similarity 129, member C
img NCI, Score=801, Pubmed Id: 12886250, UMLKSK CUI: C0023434
HumanST13P4145165suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4
img NCI, Score=801, Pubmed Id: 14499696, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 12079276, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 12079276, UMLKSK CUI: C0023434
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
Click here to display 9 evidence detail records.
HumanARL11115761ADP-ribosylation factor-like 11
img OMIM, Score=1000, UMLKSK CUI: C0023434
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
img NCI, Score=801, Pubmed Id: 16025281, UMLKSK CUI: C0023434
HumanTMEM54113452transmembrane protein 54
img NCI, Score=801, Pubmed Id: 7751474, UMLKSK CUI: C0023434
HumanBMF90427Bcl2 modifying factor
img NCI, Score=801, Pubmed Id: 14574334, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 14574334, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 15674362, UMLKSK CUI: C0023434
HumanTUBA1C84790tubulin, alpha 1c
img NCI, Score=801, Pubmed Id: 7006703, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 7006703, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 7006703, UMLKSK CUI: C0023434
HumanSETDB283852SET domain, bifurcated 2
img NCI, Score=801, Pubmed Id: 11306461, UMLKSK CUI: C0023434
HumanFERMT383706fermitin family member 3
img NCI, Score=801, Pubmed Id: 12886250, UMLKSK CUI: C0023434
HumanMAGED4B81557melanoma antigen family D, 4B
img NCI, Score=801, Pubmed Id: 7656275, UMLKSK CUI: C0023434
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023434Leukemia, Lymphocytic, Chronic, B-Cell0self