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Details
Link-It Detail - Disease - Leukemia, Lymphocytic, Chronic, B-Cell
Debug Stats
  • ### Total Build Time: 740 ms 67.550 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 432 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 354 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=11 ms Completed: 11 ms rowSize= 4.058 KB
  • CONCEPT_RELATIONSHIPS gt=534 ms Completed: 534 ms rowSize= 18.146 KB
  • CONCEPT_GENES gt=175 ms Completed: 175 ms rowSize= 42.650 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukemia, Lymphocytic, Chronic, B-Cell C0023434
Chronic Lymphocytic Leukemia
Definition (1)
chronic leukemia characterized by morphologically mature but immunologically less mature lymphocytes; manifested by an abnormal accumulation of these cells in blood, bone marrow, and lymphatic tissue.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, B-Cell C2004493
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Leukemia, B-Cell C2004493
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Leukemia, B-Cell C2004493
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, B-Cell C2004493
Relationships (271)

Relation Types:
diso_​to_​anat : 37
diso_​to_​chem : 98
diso_​to_​diso : 85
diso_​to_​gene : 34
diso_​to_​phen : 2
diso_​to_​phys : 15


Relationships:
none : 144
associated_​with : 2
classifies : 1
clinically_​similar : 5
disease_​has_​associated_​disease : 2
gene_​associated_​with_​disease : 30
gene_​product_​malfunction_​associated_​with_​disease : 2
inheritance_​type_​of : 1
is_​abnormal_​cell_​of_​disease : 9
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 4
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 19
manifestation_​of : 3
mapped_​to : 1
may_​be_​finding_​of_​disease : 2
may_​treat : 31
permuted_​term_​of : 1
related_​to : 4
Page Size
Current 25
  Page 1 of 11
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN989img genetic aspects C0017399
DISO_to_PHEN589img genetic aspects C0017399
DISO_to_DISO308img Complication Aspects C1171258
DISO_to_CHEM304img Antineoplastic Agents C0003392
DISO_to_DISO293img Complication Aspects C1171258
DISO_to_CHEM228img Antineoplastic Agents C0003392
DISO_to_ANAT216img In Blood C0005768
DISO_to_CHEM207img Antibodies, Monoclonal C0003250
DISO_to_CHEM184img Antibodies, Monoclonal C0003250
DISO_to_ANAT175img B-Lymphocytes C0004561
DISO_to_CHEM172img 9 beta Arabinofuranosyladenine C0042646
DISO_to_CHEM172img Vidarabine C0042646
DISO_to_PHYS144img Apoptosis C0162638
DISO_to_PHYS143img Apoptosis C0162638
DISO_to_ANAT136img In Blood C0005768
DISO_to_ANAT120img B-Lymphocytes C0004561
DISO_to_CHEM117img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM90img ANTIBODIES NEOPL C0003251
DISO_to_CHEM85img 9 beta Arabinofuranosyladenine C0042646
DISO_to_PHYS84img Mutation C0026882
DISO_to_CHEM82img ZAP-70 Kinase C0246976
DISO_to_CHEM77img HEAVY CHAIN IG C0021034
DISO_to_CHEM77img Immunoglobulin Heavy Chains C0021034
DISO_to_CHEM75img Antigens, CD C0003322
DISO_to_CHEM74img ANTIBODIES NEOPL C0003251
Genes (291)

Species:
human : 288
mouse : 3
Page Size
Current 25
  Page 1 of 12
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseBCL2L1110018BCL2-like 11 (apoptosis facilitator)
img NCI, Score=801, Pubmed Id: 15079075, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 15079075, UMLKSK CUI: C0023434
MouseIL33562interleukin 3 (colony-stimulating factor, multiple)
img NCI, Score=801, Pubmed Id: 8906104, UMLKSK CUI: C0023434
MouseCD22933CD22 molecule
img NCI, Score=801, Pubmed Id: 15897589, UMLKSK CUI: C0023434
HumanGGT2728441gamma-glutamyltransferase 2
img NCI, Score=801, Pubmed Id: 24319, UMLKSK CUI: C0023434
HumanCLLU1574028chronic lymphocytic leukemia up-regulated 1
Click here to display 12 evidence detail records.
HumanMIR181B2406956microRNA 181b-2
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
HumanMIR181B1406955microRNA 181b-1
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
HumanMIR181A2406954microRNA 181a-2
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 17178851, UMLKSK CUI: C0023434
HumanMIR16-2406951
img NCI, Score=801, Pubmed Id: 15737576, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 15737576, UMLKSK CUI: C0023434
HumanMIR16-1406950
Click here to display 7 evidence detail records.
HumanMIR142406934microRNA 142
img NCI, Score=801, Pubmed Id: 15737576, UMLKSK CUI: C0023434
HumanKCNRG283518potassium channel regulator
img NCI, Score=801, Pubmed Id: 12650944, UMLKSK CUI: C0023434
HumanDLEU7220107deleted in lymphocytic leukemia, 7
img NCI, Score=801, Pubmed Id: 14706829, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 14706829, UMLKSK CUI: C0023434
HumanARHGAP27201176Rho GTPase activating protein 27
img NCI, Score=801, Pubmed Id: 15492870, UMLKSK CUI: C0023434
HumanFAM129C199786family with sequence similarity 129, member C
img NCI, Score=801, Pubmed Id: 12886250, UMLKSK CUI: C0023434
HumanST13P4145165suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4
img NCI, Score=801, Pubmed Id: 12079276, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 12079276, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 14499696, UMLKSK CUI: C0023434
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
Click here to display 9 evidence detail records.
HumanARL11115761ADP-ribosylation factor-like 11
img OMIM, Score=1000, UMLKSK CUI: C0023434
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
img NCI, Score=801, Pubmed Id: 16025281, UMLKSK CUI: C0023434
HumanTMEM54113452transmembrane protein 54
img NCI, Score=801, Pubmed Id: 7751474, UMLKSK CUI: C0023434
HumanBMF90427Bcl2 modifying factor
img NCI, Score=801, Pubmed Id: 14574334, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 14574334, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 15674362, UMLKSK CUI: C0023434
HumanTUBA1C84790tubulin, alpha 1c
img NCI, Score=801, Pubmed Id: 7006703, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 7006703, UMLKSK CUI: C0023434
img NCI, Score=801, Pubmed Id: 7006703, UMLKSK CUI: C0023434
HumanSETDB283852SET domain, bifurcated 2
img NCI, Score=801, Pubmed Id: 11306461, UMLKSK CUI: C0023434
HumanFERMT383706fermitin family member 3
img NCI, Score=801, Pubmed Id: 12886250, UMLKSK CUI: C0023434
HumanMAGED4B81557melanoma antigen family D, 4B
img NCI, Score=801, Pubmed Id: 7656275, UMLKSK CUI: C0023434
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023434Leukemia, Lymphocytic, Chronic, B-Cell0self