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Details
Link-It Detail - Disease - Hypothalamic Neoplasms
Debug Stats
  • ### Total Build Time: 151 ms 37.283 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 390 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 680 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 999 bytes
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 998 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 5.362 KB
  • CONCEPT_RELATIONSHIPS gt=70 ms Completed: 70 ms rowSize= 10.144 KB
  • CONCEPT_GENES gt=44 ms Completed: 44 ms rowSize= 17.416 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Hypothalamic Neoplasms C0020659
HYPOTHALAMIC NEOPL
Definition (1)
Benign and malignant tumors of the HYPOTHALAMUS. Pilocytic astrocytomas and hamartomas are relatively frequent histologic types. Neoplasms of the hypothalamus frequently originate from adjacent structures, including the OPTIC CHIASM, optic nerve (see OPTIC NERVE NEOPLASMS), and pituitary gland (see PITUITARY NEOPLASMS). Relatively frequent clinical manifestations include visual loss, developmental delay, macrocephaly, and precocious puberty. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2051)
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Hypothalamic Diseases C0020655
img Supratentorial Neoplasms C0038874
Children (2)
img Pallister-Hall Syndrome C0265220
img Pituitary Neoplasms C0032019
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Hypothalamic Diseases C0020655
img Neoplasms C0027651img Neoplasms by Site C00276537img Supratentorial Neoplasms C0038874
img Nervous System Diseases C0027765img Nervous System Neoplasms C00277666img Supratentorial Neoplasms C0038874
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Supratentorial Neoplasms C0038874
Relationships (24)

Relation Types:
diso_​to_​anat : 7
diso_​to_​diso : 17


Relationships:
none : 12
is_​abnormal_​cell_​of_​disease : 1
is_​associated_​anatomic_​site_​of : 6
isa : 4
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO30img Complication Aspects C1171258
DISO_to_DISO24img Complication Aspects C1171258
DISO_to_DISO18img 755-756 HAMARTOMAS C0018552
DISO_to_DISO15img ASTROCYTOMA C0004114
DISO_to_DISO14img Astrocytoma C0004114
DISO_to_DISO12img Hamartoma C0018552
DISO_to_DISO9img Pituitary Neoplasms C0032019
DISO_to_DISO7img Glioma C0017638
DISO_to_DISO7img Optic Nerve Neoplasms C0524802
DISO_to_DISO6img Craniopharyngioma C0010276
DISO_to_DISO6img Glioma C0017638
DISO_to_DISO6img Glioma of Optic Nerve C0346326
DISO_to_ANATis_associated_anatomic_site_ofimg Brain C0006104
DISO_to_ANATis_associated_anatomic_site_ofimg Central Nervous System C0927232
DISO_to_ANATis_associated_anatomic_site_ofimg Diencephalon C0012144
DISO_to_ANATis_associated_anatomic_site_ofimg Hypothalamus C0020663
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_associated_anatomic_site_ofimg Nervous System C0027763
DISO_to_ANATis_associated_anatomic_site_ofimg Supratentorial Brain C1522407
DISO_to_DISOisaimg Benign tumor of hypothalamus C0347514
DISO_to_DISOpermuted_term_ofimg HYPOTHALAMIC NEOPL C0020659
DISO_to_DISOisaimg Hypothalamic Gangliocytoma C1708403
DISO_to_DISOisaimg Malignant neoplasm of hypothalamus C0346916
DISO_to_DISOisaimg Pituitary Neoplasms C0032019
Genes (98)

Species:
human : 98
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMIR16-1406950
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanHIST4H4121504histone cluster 4, H4
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTUBA1C84790tubulin, alpha 1c
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanINHBE83729inhibin, beta E
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanGHRL51738ghrelin/obestatin prepropeptide
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanIL23A51561interleukin 23, alpha subunit p19
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanANGPT451378angiopoietin 4
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanRHBDD325807rhomboid domain containing 3
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanRAB1822931RAB18, member RAS oncogene family
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanCOPS510987COP9 signalosome subunit 5
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanGADD45G10912growth arrest and DNA-damage-inducible, gamma
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanNMU10874neuromedin U
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanNES10763nestin
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanPTTG19232pituitary tumor-transforming 1
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanHGS9146hepatocyte growth factor-regulated tyrosine kinase substrate
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanAIP9049aryl hydrocarbon receptor interacting protein
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanHMGA28091high mobility group AT-hook 2
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanVEGFA7422vascular endothelial growth factor A
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTRHR7201thyrotropin-releasing hormone receptor
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTLR47099toll-like receptor 4
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTIMP27077TIMP metallopeptidase inhibitor 2
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTIMP17076TIMP metallopeptidase inhibitor 1
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTBXAS16916thromboxane A synthase 1 (platelet)
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanTAC16863tachykinin, precursor 1
INFERRED, Score=800, UMLKSK CUI: C0020659
HumanSYP6855synaptophysin
INFERRED, Score=800, UMLKSK CUI: C0020659
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020659Hypothalamic Neoplasms0self