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Details
Link-It Detail - Disease - Hyperpituitarism
Debug Stats
  • ### Total Build Time: 517 ms 30.682 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 492 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=9 ms Completed: 9 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=68 ms Completed: 68 ms rowSize= 554 bytes
  • CONCEPT_CHILDREN gt=66 ms Completed: 66 ms rowSize= 1.815 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=22 ms Completed: 22 ms rowSize= 2.794 KB
  • CONCEPT_RELATIONSHIPS gt=303 ms Completed: 303 ms rowSize= 6.285 KB
  • CONCEPT_GENES gt=33 ms Completed: 33 ms rowSize= 17.082 KB
  • CONCEPT_XREFS gt=9 ms Completed: 9 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hyperpituitarism C0020506
Definition (1)
Disease of the glandular, anterior portion of the pituitary (PITUITARY GLAND, ANTERIOR) resulting in hypersecretion of ADENOHYPOPHYSEAL HORMONES such as GROWTH HORMONE; PROLACTIN; THYROTROPIN; LUTEINIZING HORMONE; FOLLICLE STIMULATING HORMONE ; and ADRENOCORTICOTROPIC HORMONE. Hyperpituitarism usually is caused by a functional ADENOMA.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Pituitary Diseases C0032002
Children (4)
img Acromegaly C0001206
img Gigantism C0017547
img Pituitary ACTH Hypersecretion C0221406
img Hyperprolactinemia C0020514
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Pituitary Diseases C0032002
img Endocrine System Diseases C0014130img Pituitary Diseases C00320023img Pituitary Diseases C0032002
Relationships (14)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 2
diso_​to_​diso : 10


Relationships:
none : 6
isa : 7
location_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO3img Adenoma C0001430
DISO_to_DISO3img Pituitary Neoplasms C0032019
DISO_to_ANAT2img In Blood C0005768
DISO_to_CHEM2img Thyrotropin C0040160
DISO_to_CHEM2img Thyroxine C0040165
DISO_to_DISO2img Complication Aspects C1171258
DISO_to_ANATlocation_ofimg Pituitary Gland, Anterior C0032008
DISO_to_DISOisaimg ACTH hypersecretion C0342362
DISO_to_DISOisaimg Acromegaly and gigantism C0405578
DISO_to_DISOisaimg Gonadotrophin hypersecretion C0342365
DISO_to_DISOisaimg Growth hormone overproduction C0271547
DISO_to_DISOisaimg Hyperpituitarism, prepubertal C1263952
DISO_to_DISOisaimg Hyperprolactinemia C0020514
DISO_to_DISOisaimg Overproduction of TSH C0271551
Genes (33)

Species:
human : 33
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPRX57716periaxin
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanAICDA57379activation-induced cytidine deaminase
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanGHRL51738ghrelin/obestatin prepropeptide
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanSOST50964sclerostin
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanRAB1822931RAB18, member RAS oncogene family
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanSLC35A110559solute carrier family 35 (CMP-sialic acid transporter), member A1
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanAIP9049aryl hydrocarbon receptor interacting protein
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanGAN8139gigaxonin
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanSSTR56755somatostatin receptor 5
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanSSTR26752somatostatin receptor 2
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanSMARCA46597SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanPTH5741parathyroid hormone
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanPRL5617prolactin
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanPRKAR1A5573protein kinase, cAMP-dependent, regulatory, type I, alpha
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanPOMC5443proopiomelanocortin
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanNPPB4879natriuretic peptide B
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanMYH94627myosin, heavy chain 9, non-muscle
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanMEN14221multiple endocrine neoplasia I
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanLPL4023lipoprotein lipase
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanINS3630insulin
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanIGFBP33486insulin-like growth factor binding protein 3
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanIGF13479insulin-like growth factor 1 (somatomedin C)
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanHDAC23066histone deacetylase 2
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanNR3C12908nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
INFERRED, Score=800, UMLKSK CUI: C0020506
HumanGNAS2778GNAS complex locus
INFERRED, Score=800, UMLKSK CUI: C0020506
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020506Hyperpituitarism0self