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Details
Link-It Detail - Disease - Hydatidiform Mole
Debug Stats
  • ### Total Build Time: 379 ms 60.046 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.054 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 569 bytes
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 565 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=16 ms Completed: 16 ms rowSize= 4.131 KB
  • CONCEPT_RELATIONSHIPS gt=55 ms Completed: 55 ms rowSize= 14.365 KB
  • CONCEPT_GENES gt=276 ms Completed: 276 ms rowSize= 37.703 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hydatidiform Mole C0020217
Definition (1)
A gestational disorder characterized by an abnormal placenta with marked enlargement of the chorionic villi and hyperplasia of the villous trophoblastic cells. According to the amount of villous involvement, a hydatidiform mole is defined as complete or partial. Most molar pregnancies are complete and are characterized by generalized hydropic villous changes. Partial moles are characterized by a mixture of large hydropic villi and normal placenta tissue. Complete moles are usually diploid and typically present between the eleventh and twenty-fifth week of pregnancy, whereas partial moles are usually triploid and usually present around the nineteenth week of pregnancy. The incidence of choriocarcinoma is higher in patients with complete hydatidiform mole. When a hydatidiform mole invades the myometrium and broad ligament, or it is found in distant sites as vagina, vulva, and lung, it is referred as invasive mole.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Gestational Trophoblastic Disease C1135868
Children (1)
img Hydatidiform Mole, Invasive C0008493
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Gestational Trophoblastic Disease C1135868
img Neoplasms C0027651img Pregnancy Complications, Neoplastic C00329665img Gestational Trophoblastic Disease C1135868
img Female Urogenital Diseases and Pregnancy Complications C1720765img Pregnancy Complications C00329626img Gestational Trophoblastic Disease C1135868
Relationships (48)

Relation Types:
diso_​to_​anat : 11
diso_​to_​chem : 6
diso_​to_​diso : 29
diso_​to_​phen : 2


Relationships:
none : 24
associated_​with : 2
classifies : 2
is_​abnormal_​cell_​of_​disease : 2
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
isa : 3
location_​of : 2
mapped_​to : 5
permuted_​term_​of : 1
use : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO201img NEOPL UTERINE C0042138
DISO_to_DISO200img NEOPL UTERINE C0042138
DISO_to_PHEN94img genetic aspects C0017399
DISO_to_PHEN81img genetic aspects C0017399
DISO_to_DISO47img Complication Aspects C1171258
DISO_to_ANAT42img In Blood C0005768
DISO_to_DISO41img Complication Aspects C1171258
DISO_to_ANAT39img In Blood C0005768
DISO_to_DISO28img Choriocarcinoma C0008497
DISO_to_DISO25img Gestational trophoblastic disease C2931618
DISO_to_DISO24img Choriocarcinoma C0008497
DISO_to_CHEM23img Chorionic Gonadotropin C0018062
DISO_to_DISO22img COMPL NEOPL PREGN C0032966
DISO_to_ANAT20img Placenta C0032043
DISO_to_DISO19img COMPL NEOPL PREGN C0032966
DISO_to_DISO19img Gestational trophoblastic disease C2931618
DISO_to_ANAT17img Placenta C0032043
DISO_to_CHEM17img Chorionic Gonadotropin C0018062
DISO_to_CHEM16img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM16img Nuclear Proteins C0028589
DISO_to_DISO15img Abortion, Spontaneous C0000786
DISO_to_CHEM14img Adaptor Proteins, Signal Transducing C1449886
DISO_to_CHEM14img Cyclin-Dependent Kinase Inhibitor p57 C0296845
DISO_to_DISO14img Ectopic Pregnancy C0032987
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
Genes (35)

Species:
human : 35
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanERVK7449619
img NCI, Score=801, Pubmed Id: 8909261, UMLKSK CUI: C0020217
HumanNLRP7199713NLR family, pyrin domain containing 7
img GENERIF, Score=901, Pubmed Id: 18039680, UMLKSK CUI: C0020217
img OMIM, Score=1000, UMLKSK CUI: C0020217
img GENERIF, Score=901, Pubmed Id: 16462743, UMLKSK CUI: C0020217
img GENERIF, Score=1000, Pubmed Id: 16501554, UMLKSK CUI: C0020217
img GENERIF, Score=861, Pubmed Id: 17579354, UMLKSK CUI: C0020217
img GENERIF, Score=734, Pubmed Id: 16874523, UMLKSK CUI: C0020217
HumanPSCA8000prostate stem cell antigen
img GENERIF, Score=1000, Pubmed Id: 18184265, UMLKSK CUI: C0020217
HumanTJP17082tight junction protein 1
img NCI, Score=801, Pubmed Id: 11228248, UMLKSK CUI: C0020217
img NCI, Score=801, Pubmed Id: 11228248, UMLKSK CUI: C0020217
HumanTERC7012telomerase RNA component
img NCI, Score=801, Pubmed Id: 10329353, UMLKSK CUI: C0020217
HumanRFC25982replication factor C (activator 1) 2, 40kDa
img NCI, Score=801, Pubmed Id: 14960244, UMLKSK CUI: C0020217
HumanRASA15921RAS p21 protein activator (GTPase activating protein) 1
img NCI, Score=801, Pubmed Id: 7747802, UMLKSK CUI: C0020217
HumanPZP5858pregnancy-zone protein
INFERRED, Score=800, UMLKSK CUI: C0020217
HumanPTEN5728phosphatase and tensin homolog
img GENERIF, Score=1000, Pubmed Id: 15784509, UMLKSK CUI: C0020217
HumanPEG35178paternally expressed 3
img NCI, Score=801, Pubmed Id: 11677152, UMLKSK CUI: C0020217
img NCI, Score=801, Pubmed Id: 11677152, UMLKSK CUI: C0020217
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img NCI, Score=801, Pubmed Id: 9415517, UMLKSK CUI: C0020217
img NCI, Score=801, Pubmed Id: 9415517, UMLKSK CUI: C0020217
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 11408732, UMLKSK CUI: C0020217
img NCI, Score=801, Pubmed Id: 11408732, UMLKSK CUI: C0020217
img NCI, Score=801, Pubmed Id: 11408732, UMLKSK CUI: C0020217
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 16884384, UMLKSK CUI: C0020217
HumanMEST4232mesoderm specific transcript
img NCI, Score=801, Pubmed Id: 8884280, UMLKSK CUI: C0020217
HumanMCM74176minichromosome maintenance complex component 7
img NCI, Score=801, Pubmed Id: 14636275, UMLKSK CUI: C0020217
HumanIDO13620indoleamine 2,3-dioxygenase 1
img GENERIF, Score=1000, Pubmed Id: 19004406, UMLKSK CUI: C0020217
HumanIGFBP13484insulin-like growth factor binding protein 1
img NCI, Score=801, Pubmed Id: 2444151, UMLKSK CUI: C0020217
img NCI, Score=801, Pubmed Id: 6318674, UMLKSK CUI: C0020217
HumanID43400inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 16115231, UMLKSK CUI: C0020217
HumanID33399inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 16115231, UMLKSK CUI: C0020217
HumanID23398inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 16115231, UMLKSK CUI: C0020217
HumanID13397inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 16115231, UMLKSK CUI: C0020217
HumanGPC12817glypican 1
img NCI, Score=801, Pubmed Id: 10629564, UMLKSK CUI: C0020217
HumanERV32086endogenous retrovirus group 3, member 1
img NCI, Score=801, Pubmed Id: 7716822, UMLKSK CUI: C0020217
HumanEPOR2057erythropoietin receptor
img GENERIF, Score=1000, Pubmed Id: 18479804, UMLKSK CUI: C0020217
HumanEPO2056erythropoietin
img GENERIF, Score=1000, Pubmed Id: 18479804, UMLKSK CUI: C0020217
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020217Hydatidiform Mole0self