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Details
Link-It Detail - Disease - Glomerulonephritis, Membranous
Debug Stats
  • ### Total Build Time: 24 ms 27.325 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 358 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 466 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 991 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.092 KB
  • CONCEPT_RELATIONSHIPS gt=13 ms Completed: 13 ms rowSize= 13.364 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 6.714 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Glomerulonephritis, Membranous C0017665
Definition (1)
A type of glomerulonephritis that is characterized by the accumulation of immune deposits (COMPLEMENT MEMBRANE ATTACK COMPLEX) on the outer aspect of the GLOMERULAR BASEMENT MEMBRANE. It progresses from subepithelial dense deposits, to basement membrane reaction and eventual thickening of the basement membrane.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Autoimmune Diseases C0004364
img Glomerulonephritis C0017658
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Autoimmune Diseases C00043643img Autoimmune Diseases C0004364
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208877img Glomerulonephritis C0017658
img Male Urogenital Diseases C1720894img Urologic Diseases C00420756img Glomerulonephritis C0017658
Relationships (51)

Relation Types:
diso_​to_​anat : 11
diso_​to_​chem : 12
diso_​to_​diso : 26
diso_​to_​phen : 2


Relationships:
none : 39
associated_​with : 1
is_​associated_​anatomic_​site_​of : 2
isa : 6
location_​of : 1
permuted_​term_​of : 1
use : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO130img Complication Aspects C1171258
DISO_to_DISO89img Complication Aspects C1171258
DISO_to_DISO49img Nephrotic Syndrome C0027726
DISO_to_CHEM48img Immunosuppressive Agents C0021081
DISO_to_PHEN39img genetic aspects C0017399
DISO_to_CHEM34img Immunosuppressive Agents C0021081
DISO_to_ANAT28img Kidney C0022646
DISO_to_CHEM27img PHOSPHOLIPASE A 02 RECEPTOR C0250850
DISO_to_DISO26img Nephrotic Syndrome C0027726
DISO_to_CHEM25img Antibodies, Monoclonal C0003250
DISO_to_DISO25img Proteinuria C0033687
DISO_to_ANAT23img Kidney Glomerulus C0022663
DISO_to_PHEN23img genetic aspects C0017399
DISO_to_DISO21img Focal glomerulosclerosis C0017668
DISO_to_ANAT20img Kidney C0022646
DISO_to_ANAT19img Epithelial Cells, Glomerular Visceral C1328818
DISO_to_CHEM19img Immunoglobulin G C0020852
DISO_to_CHEM18img Immunologic Factors C0021054
DISO_to_DISO18img Proteinuria C0033687
DISO_to_DISO18img chemically induced C0007994
DISO_to_CHEM17img Abs - Autoantibodies C0004358
DISO_to_DISO16img (Nephrotic syndrome in systemic lupus erythematosus) or (lupus nephritis) C0024143
DISO_to_ANAT15img In Blood C0005768
DISO_to_DISO15img (Nephrotic syndrome in systemic lupus erythematosus) or (lupus nephritis) C0024143
DISO_to_CHEM14img Cyclophosphamide C0010583
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanPRKCB5579protein kinase C, beta
img GENERIF, Score=734, Pubmed Id: 16775601, UMLKSK CUI: C0017665
HumanPRKCA5578protein kinase C, alpha
img GENERIF, Score=734, Pubmed Id: 16775601, UMLKSK CUI: C0017665
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
img GENERIF, Score=901, Pubmed Id: 18495745, UMLKSK CUI: C0017665
HumanMME4311membrane metallo-endopeptidase
img GENERIF, Score=901, Pubmed Id: 15464186, UMLKSK CUI: C0017665
HumanCLU1191clusterin
img GENERIF, Score=1000, Pubmed Id: 16775601, UMLKSK CUI: C0017665
HumanCASP10843caspase 10, apoptosis-related cysteine peptidase
img OMIM, Score=1000, UMLKSK CUI: C0017665
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0017665Glomerulonephritis, Membranous0self