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Details
Link-It Detail - Disease - Glomerulonephritis, Membranoproliferative
Debug Stats
  • ### Total Build Time: 171 ms 22.767 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 445 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 645 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=16 ms Completed: 16 ms rowSize= 994 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=18 ms Completed: 18 ms rowSize= 3.697 KB
  • CONCEPT_RELATIONSHIPS gt=111 ms Completed: 111 ms rowSize= 13.264 KB
  • CONCEPT_GENES gt=9 ms Completed: 9 ms rowSize= 2.377 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.175 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Glomerulonephritis, Membranoproliferative C0017662
Chronic glomerulonephritis, lobular
Definition (1)
Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Immune System Diseases C0021053
img Glomerulonephritis C0017658
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C00210532img Immune System Diseases C0021053
img Male Urogenital Diseases C1720894img Urologic Diseases C00420756img Glomerulonephritis C0017658
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208877img Glomerulonephritis C0017658
Relationships (52)

Relation Types:
diso_​to_​anat : 9
diso_​to_​chem : 11
diso_​to_​diso : 30
diso_​to_​phen : 2


Relationships:
none : 40
associated_​with : 1
entry_​version_​of : 1
is_​associated_​anatomic_​site_​of : 2
isa : 5
location_​of : 1
mapped_​to : 2
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO65img Complication Aspects C1171258
DISO_to_DISO54img Complication Aspects C1171258
DISO_to_PHEN39img genetic aspects C0017399
DISO_to_ANAT26img In Blood C0005768
DISO_to_ANAT25img Glomerular Mesangium C0017655
DISO_to_ANAT21img Kidney Glomerulus C0022663
DISO_to_DISO21img Hepatitis C C0019196
DISO_to_PHEN21img genetic aspects C0017399
DISO_to_DISO20img Cryoglobulinemia C0010403
DISO_to_ANAT19img Kidney C0022646
DISO_to_CHEM17img COMPLEMENT FACTOR H C0056207
DISO_to_DISO17img CRYOGLOBULINEMIA C0010403
DISO_to_DISO15img Chronic Hepatitis C C0524910
DISO_to_DISO14img chemically induced C0007994
DISO_to_DISO13img Glomerulonephritis, Membranous C0017665
DISO_to_DISO13img Hepatitis C C0019196
DISO_to_CHEM12img Antiviral Agents C0003451
DISO_to_DISO12img Hemolytic-Uremic Syndrome C0019061
DISO_to_DISO12img Nephrotic Syndrome C0027726
DISO_to_CHEM11img Immunosuppressive Agents C0021081
DISO_to_DISO11img Nephrotic Syndrome C0027726
DISO_to_ANAT10img In Blood C0005768
DISO_to_CHEM10img Immunosuppressive Agents C0021081
DISO_to_DISO10img Age related macular degeneration C0242383
DISO_to_DISO10img Paraproteinemias C0030489
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanLMNB284823lamin B2
img OMIM, Score=1000, UMLKSK CUI: C0017662
HumanPON15444paraoxonase 1
img GENERIF, Score=1000, Pubmed Id: 16175651, UMLKSK CUI: C0017662
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0017662Glomerulonephritis, Membranoproliferative0self