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Details
Link-It Detail - Disease - Glaucoma
Debug Stats
  • ### Total Build Time: 535 ms 50.362 KB
  • CONCEPT_NAME gt=16 ms Completed: 16 ms rowSize= 314 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 972 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 555 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.405 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 1.498 KB
  • CONCEPT_RELATIONSHIPS gt=89 ms Completed: 89 ms rowSize= 15.050 KB
  • CONCEPT_GENES gt=423 ms Completed: 423 ms rowSize= 29.258 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.143 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Glaucoma C0017601
Definition (1)

Glaucoma damages the eye's optic nerve. It is a leading cause of blindness in the United States. It usually happens when the fluid pressure inside the eyes slowly rises, damaging the optic nerve. Often there are no symptoms at first, but a comprehensive eye exam can detect it.

People at risk should get eye exams at least every two years. They include

  • African Americans over age 40
  • People over age 60, especially Mexican Americans
  • People with a family history of glaucoma

Early treatment can help protect your eyes against vision loss. Treatments usually include prescription eyedrops and/or surgery.

NIH: National Eye Institute

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Ocular Hypertension C0028840
Children (3)
img Glaucoma, Open-Angle C0017612
img Glaucoma, Angle-Closure C0017605
img Glaucoma, Neovascular C0017609
Ancestral Roots
RootRoot Plus OneDepthParent
img Eye Diseases C0015397img Ocular Hypertension C00288403img Ocular Hypertension C0028840
Relationships (231)

Relation Types:
diso_​to_​anat : 33
diso_​to_​chem : 78
diso_​to_​diso : 108
diso_​to_​gene : 1
diso_​to_​phen : 2
diso_​to_​phys : 9


Relationships:
none : 116
classified_​as : 29
gene_​is_​biomarker_​of : 1
gene_​product_​is_​biomarker_​of : 1
is_​associated_​anatomic_​site_​of : 1
isa : 16
mapped_​to : 21
may_​treat : 39
parent_​is_​cdrh : 1
related_​to : 2
use : 4
Page Size
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  Page 1 of 10
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHYS347img Intraocular Pressure C0021888
DISO_to_PHYS299img Intraocular Pressure C0021888
DISO_to_ANAT290img Cell, Retinal Ganglion C0035316
DISO_to_DISO279img Disorder of the optic nerve C0029132
DISO_to_ANAT273img Optic Disk C0029127
DISO_to_DISO273img Complication Aspects C1171258
DISO_to_DISO221img Complication Aspects C1171258
DISO_to_CHEM200img Antihypertensive Agents C0003364
DISO_to_PHEN195img genetic aspects C0017399
DISO_to_DISO171img Disorder of the optic nerve C0029132
DISO_to_ANAT158img Optic Disk C0029127
DISO_to_ANAT153img Nerve Fiber C0027749
DISO_to_CHEM150img Antihypertensive Agents C0003364
DISO_to_ANAT140img Cell, Retinal Ganglion C0035316
DISO_to_PHEN132img genetic aspects C0017399
DISO_to_DISO113img Vision Disorders C0042790
DISO_to_DISO100img HYPERTENSION OCULAR C0028840
DISO_to_ANAT98img Retina C0035298
DISO_to_DISO97img Cataract C0086543
DISO_to_DISO95img Vision Disorders C0042790
DISO_to_ANAT93img Cornea C0010031
DISO_to_ANAT86img Nerve Fiber C0027749
DISO_to_DISO86img Animal Disease Models C0012644
DISO_to_DISO80img COMPL POSTOP C0032787
DISO_to_ANAT75img Cornea C0010031
Genes (88)

Species:
human : 88
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanVSX2338917visual system homeobox 2
INFERRED, Score=800, UMLKSK CUI: C0017601
HumanWDR36134430WD repeat domain 36
img GENERIF, Score=827, Pubmed Id: 15677485, UMLKSK CUI: C0017601
img GENERIF, Score=1000, Pubmed Id: 18172102, UMLKSK CUI: C0017601
img GENERIF, Score=827, Pubmed Id: 17960130, UMLKSK CUI: C0017601
img GENERIF, Score=660, Pubmed Id: 16723468, UMLKSK CUI: C0017601
HumanMFRP83552membrane frizzled-related protein
INFERRED, Score=800, UMLKSK CUI: C0017601
HumanSBF281846SET binding factor 2
img OMIM, Score=1000, UMLKSK CUI: C0017601
img OMIM, Score=1000, UMLKSK CUI: C0017601
img GENERIF, Score=827, Pubmed Id: 15304601, UMLKSK CUI: C0017601
img OMIM, Score=1000, UMLKSK CUI: C0017601
img GENERIF, Score=827, Pubmed Id: 12687498, UMLKSK CUI: C0017601
HumanADAMTS1081794ADAM metallopeptidase with thrombospondin type 1 motif, 10
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanFKRP79147fukutin related protein
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanNOD264127nucleotide-binding oligomerization domain containing 2
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanBTNL256244butyrophilin-like 2 (MHC class II associated)
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanPEX2655670peroxisomal biogenesis factor 26
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanPOMGNT155624protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanAGGF155109angiogenic factor with G patch and FHA domains 1
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanVSX130813visual system homeobox 1
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanPOMT229954protein-O-mannosyltransferase 2
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanOCLM10896oculomedin
img GENERIF, Score=1000, Pubmed Id: 12655282, UMLKSK CUI: C0017601
HumanVAMP510791vesicle-associated membrane protein 5
img GAD, Score=1000, Pubmed Id: 16110299, UMLKSK CUI: C0017601
HumanEBP10682emopamil binding protein (sterol isomerase)
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanPOMT110585protein-O-mannosyltransferase 1
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanANGPTL710218angiopoietin-like 7
img GENERIF, Score=1000, Pubmed Id: 18421092, UMLKSK CUI: C0017601
HumanOPTN10133optineurin
Click here to display 9 evidence detail records.
HumanRECQL49401RecQ protein-like 4
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanLARGE9215like-glycosyltransferase
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanVAMP88673vesicle-associated membrane protein 8
img GAD, Score=1000, Pubmed Id: 16110299, UMLKSK CUI: C0017601
HumanSLC4A48671solute carrier family 4 (sodium bicarbonate cotransporter), member 4
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanPEX38504peroxisomal biogenesis factor 3
img OMIM, Score=1000, UMLKSK CUI: C0017601
HumanNCK28440NCK adaptor protein 2
img GENERIF, Score=1000, Pubmed Id: 18723748, UMLKSK CUI: C0017601
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0017601Glaucoma0self