Human | DEFB103B | 55894 | defensin, beta 103B | Our results suggest that like hBD-2, hBD-3 may be involved in the pathophysiology of H. pylori-induced gastritis |
Human | L1TD1 | 54596 | LINE-1 type transposase domain containing 1 | LINE-1 hypomethylation is significantly associated with CpG island hypermethylation in EF+ gastritis |
Human | GHRL | 51738 | ghrelin/obestatin prepropeptide | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | CYSLTR1 | 10800 | cysteinyl leukotriene receptor 1 | Report the long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carcinogenesis |
Human | MADCAM1 | 8174 | mucosal vascular addressin cell adhesion molecule 1 | MAdCAM-1/integrin alpha4beta7 homing system may participate in gastric inflammation in response to H pylori-infection and contributes to MALT formation, typically leading to the development of nodular gastritis |
Human | SSPN | 8082 | sarcospan | Title:K-ras mutation in helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.|Association:Not Found|Conclusion:These data suggest that the genetic mechanism(s) of carcinogenesis differs between the differentiated type and the undifferentiated type of gastric cancer and that K-ras mutations may be involved in the early stages of gastric carcinogenesis of the differentiated type. |
Human | UCN | 7349 | urocortin | a highly significant, but negative, correlation has been found between Ucn levels and gastric inflammation, suggesting that Ucn may exert an antiinflammatory effect in gastric mucosa |
Human | TNF | 7124 | tumor necrosis factor | INFERRED, Score=800, UMLKSK CUI: C0017152 -308 A allele may increase risk of gastritis and lymphoid follicle formation |
Human | TLR4 | 7099 | toll-like receptor 4 | TLR-4 Thr399Ileu substitution may be a risk factor for gastritis and precancerous lesions |
Human | TLR2 | 7097 | toll-like receptor 2 | We did not find any association between TLR2 polymorphism and risk of gastric ulcer, duodenal ulcer, gastric and duodenal ulcer and gastritis compared to healthy controls |
Human | TGFA | 7039 | transforming growth factor, alpha | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | SPINK1 | 6690 | serine peptidase inhibitor, Kazal type 1 | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | SHH | 6469 | sonic hedgehog | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | CCL20 | 6364 | chemokine (C-C motif) ligand 20 | Interaction between CCL20 and CCR6 may play a role in chemokine-mediated lymphocyte trafficking during gastric inflammation in Helicobacter infection |
Human | PTPN11 | 5781 | protein tyrosine phosphatase, non-receptor type 11 | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Results showed a stepwise increase in the expression of COX-2 as mucosal damage progressed from normal to gastritis to gastric ulcer |
Human | PTGS1 | 5742 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | Results showed a stepwise increase in the expression of COX-1 as mucosal damage progressed from normal to gastritis to gastric ulcer |
Human | PIK3CA | 5290 | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | SERPINA1 | 5265 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | The degradation or metabolization of acute-phase proteins, apolipoprotein A-I, and alpha1-antitrypsin, is a common response to gastric inflammation irrespective of Hp infection |
Human | NFKB1 | 4790 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | These findings suggested that expression of NF-kappaB has an important role in H. pylori gastritis |
Human | NFE2L2 | 4780 | nuclear factor, erythroid 2-like 2 | Nrf2 gene may be associated with the development of gastric inflammation and with gastric carcinogenesis the promoter polymorphisms of Nrf2 gene may affect the methylation status of tumor-related genes, especially the p14 gene, under the influence of H. pylori-induced gastric inflammation |
Human | MUTYH | 4595 | mutY homolog (E. coli) | INFERRED, Score=800, UMLKSK CUI: C0017152 |
Human | MUC1 | 4582 | mucin 1, cell surface associated | Title:Altered expression and allelic association of the hypervariable membrane mucin MUC1 in Helicobacter pylori gastritis|Association:Y|Conclusion:Our results suggest that H. pylori interacts with MUC1 and that there are functional allelic differences that affect susceptibility to gastritis. |
Human | MMP9 | 4318 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | MMP-9 induction by H. pylori may play an important role in gastric inflammation, ulcer formation, and carcinogenesis |
Human | MLH1 | 4292 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | While CDH1 methylation seems to be an early event in Hp gastritis, MLH1 methylation occurs late along with IM |