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Details
Link-It Detail - Disease - Gastrinoma
Debug Stats
  • ### Total Build Time: 176 ms 44.412 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 318 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 641 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 557 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=16 ms Completed: 16 ms rowSize= 6.616 KB
  • CONCEPT_RELATIONSHIPS gt=132 ms Completed: 132 ms rowSize= 14.362 KB
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 20.591 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.145 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Gastrinoma C0017150
Definition (1)
A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Carcinoma, Islet Cell C1328479
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Digestive System Neoplasms C00122435img Carcinoma, Islet Cell C1328479
img Neoplasms C0027651img Neoplasms by Site C00276536img Carcinoma, Islet Cell C1328479
img Digestive System Diseases C0012242img Pancreatic Diseases C00302865img Carcinoma, Islet Cell C1328479
img Endocrine System Diseases C0014130img Endocrine Gland Neoplasms C00141325img Carcinoma, Islet Cell C1328479
img Neoplasms C0027651img Neoplasms by Histologic Type C00276527img Carcinoma, Islet Cell C1328479
Relationships (38)

Relation Types:
diso_​to_​anat : 12
diso_​to_​chem : 1
diso_​to_​diso : 25


Relationships:
none : 12
associated_​with : 1
is_​abnormal_​cell_​of_​disease : 4
is_​finding_​of_​disease : 7
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 4
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO69img Pancreatic Neoplasm C0030297
DISO_to_DISO58img Pancreatic Neoplasm C0030297
DISO_to_DISO29img Duodenal Neoplasms C0013291
DISO_to_DISO26img Multiple Endocrine Neoplasia Type 1 C0025267
DISO_to_DISO21img Zollinger-Ellison Syndrome C0043515
DISO_to_DISO19img DUODENAL NEOPL C0013291
DISO_to_DISO19img Multiple Endocrine Neoplasia Type 1 C0025267
DISO_to_DISO19img Zollinger-Ellison Syndrome C0043515
DISO_to_CHEM17img Gastrins C0017151
DISO_to_DISO17img Complication Aspects C1171258
DISO_to_DISO17img Insulinoma C0021670
DISO_to_ANAT15img In Blood C0005768
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Digestive System C0012240
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Endocrine System C0014136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Enteroendocrine Cell C0524979
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Enteroendocrine Cells C0524979
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Endocrine Cell C1513951
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Neuroendocrine Cell C1514044
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOpermuted_term_ofimg G Cell Tumor C0017150
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanSYP6855synaptophysin
img NCI, Score=801, Pubmed Id: 10835515, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 3118696, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 10835515, UMLKSK CUI: C0017150
HumanSCTR6344secretin receptor
img NCI, Score=801, Pubmed Id: 11832464, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 6095476, UMLKSK CUI: C0017150
img GENERIF, Score=1000, Pubmed Id: 17711922, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 12234988, UMLKSK CUI: C0017150
HumanNMB4828neuromedin B
img NCI, Score=801, Pubmed Id: 8943970, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 2101791, UMLKSK CUI: C0017150
HumanMEN14221multiple endocrine neoplasia I
img GENERIF, Score=1000, Pubmed Id: 17766710, UMLKSK CUI: C0017150
img GENERIF, Score=861, Pubmed Id: 15944766, UMLKSK CUI: C0017150
HumanIGF1R3480insulin-like growth factor 1 receptor
img GENERIF, Score=1000, Pubmed Id: 15867218, UMLKSK CUI: C0017150
HumanIAPP3375islet amyloid polypeptide
img NCI, Score=801, Pubmed Id: 7754100, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 7754100, UMLKSK CUI: C0017150
HumanGHRH2691growth hormone releasing hormone
img NCI, Score=801, Pubmed Id: 3102308, UMLKSK CUI: C0017150
HumanGAST2520gastrin
img NCI, Score=801, Pubmed Id: 3034736, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 2296587, UMLKSK CUI: C0017150
img GENERIF, Score=1000, Pubmed Id: 17006979, UMLKSK CUI: C0017150
HumanERBB22064v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
img GENERIF, Score=1000, Pubmed Id: 12097278, UMLKSK CUI: C0017150
HumanCXADR1525coxsackie virus and adenovirus receptor
img NCI, Score=801, Pubmed Id: 11787938, UMLKSK CUI: C0017150
HumanCASR846calcium-sensing receptor
img NCI, Score=801, Pubmed Id: 11787938, UMLKSK CUI: C0017150
img NCI, Score=801, Pubmed Id: 11787938, UMLKSK CUI: C0017150
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0017150Gastrinoma0self