Human | EDARADD | 128178 | EDAR-associated death domain | Intolerance to heat and fever |
Human | NLRP3 | 114548 | NLR family, pyrin domain containing 3 | |
Human | GPR98 | 84059 | G protein-coupled receptor 98 | A nonsense mutation (S2652X) causing a deletion of the C-terminal 126 amino acid residues was identified in one family with febrile and afebrile seizures Seizures, generalized, associated with fever |
Human | NOD2 | 64127 | nucleotide-binding oligomerization domain containing 2 | |
Human | BTNL2 | 56244 | butyrophilin-like 2 (MHC class II associated) | |
Human | KIF1B | 23095 | kinesin family member 1B | |
Human | CTRC | 11330 | chymotrypsin C (caldecrin) | |
Human | ADAMTS13 | 11093 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 | |
Human | EDAR | 10913 | ectodysplasin A receptor | Intolerance to heat and fever |
Human | MASP2 | 10747 | mannan-binding lectin serine peptidase 2 | In this study, MASP-2 deficiency was associated with an increased risk of fever and neutropenia in children treated with chemotherapy for cancer |
Human | CRLF1 | 9244 | cytokine receptor-like factor 1 | Peaks of irregular hyperthermia |
Human | PHOX2B | 8929 | paired-like homeobox 2b | |
Human | EIF2B5 | 8893 | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | Chronic-progressive course with episodes of rapid deterioration following fever or head trauma |
Human | EIF2B2 | 8892 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | Chronic-progressive course with episodes of rapid deterioration following fever or head trauma |
Human | EIF2B3 | 8891 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | Chronic-progressive course with episodes of rapid deterioration following fever or head trauma |
Human | EIF2B4 | 8890 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | Chronic-progressive course with episodes of rapid deterioration following fever or head trauma |
Human | TP63 | 8626 | tumor protein p63 | Hyperthermia in early childhood |
Human | IKBKAP | 8518 | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein | |
Human | TRPV1 | 7442 | transient receptor potential cation channel, subfamily V, member 1 | Testicular hyperthermia in mice lacking transient receptor potential vanilloid receptor-1 results in a much more rapid and massive germ cell depletion from the seminiferous tubules than in wild-type animals |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Hyperthermia acts as an anti-angiogenic strategy by suppressing VEGF expression & thus inhibiting endothelial proliferation and blood vessel ECM remodeling |
Human | TTR | 7276 | transthyretin | Extended high-temperature incubation of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S successfully removes heterogeneities and allows the reproducible growth of well diffracting crystals |
Human | TP53 | 7157 | tumor protein p53 | MMS-induced micronuclei were eliminated under mild hyperthermia via TP53 metabolism in lymphocytes |
Human | TNFRSF1A | 7132 | tumor necrosis factor receptor superfamily, member 1A | Periodic fever syndrome is associated with Tumor necrosis factor receptor-1A mutation C30R (cysteine to arginine) in a Japanese family Fever, periodic, recurrent |
Human | TNF | 7124 | tumor necrosis factor | Carriers of the TNF-alpha appeared to have an increased risk of stroke in association with a febrile episode prior to strokes The inhibition of TNF-alpha appears to be mediated primarily by exercise and not hyperthermia induced by protective clothing |
Human | TIMP1 | 7076 | TIMP metallopeptidase inhibitor 1 | TIMP-1 protein levels were significantly elevated among Kawasaki disease patients, compared to those of febrile and afebrile controls |