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Details
Link-It Detail - Disease - Epilepsy, Temporal Lobe
Debug Stats
  • ### Total Build Time: 48 ms 54.567 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 783 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 555 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.521 KB
  • CONCEPT_RELATIONSHIPS gt=27 ms Completed: 27 ms rowSize= 13.900 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 36.077 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Epilepsy, Temporal Lobe C0014556
CONVULSION PSYCHOMOTOR
Definition (1)
A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Epilepsies, Partial C0014547
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Epilepsies, Partial C0014547
Relationships (119)

Relation Types:
diso_​to_​anat : 25
diso_​to_​chem : 30
diso_​to_​diso : 45
diso_​to_​phen : 2
diso_​to_​phys : 17


Relationships:
none : 92
associated_​with : 1
clinically_​similar : 1
isa : 3
mapped_​to : 1
may_​treat : 18
permuted_​term_​of : 1
used_​for : 2
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT383img Hippocampus C0019564
DISO_to_ANAT326img Hippocampus C0019564
DISO_to_DISO261img Complication Aspects C1171258
DISO_to_ANAT244img Temporal Lobe C0039485
DISO_to_ANAT198img Temporal Lobe C0039485
DISO_to_DISO166img Complication Aspects C1171258
DISO_to_DISO131img chemically induced C0007994
DISO_to_PHEN117img genetic aspects C0017399
DISO_to_PHEN110img genetic aspects C0017399
DISO_to_PHYS108img Functional Laterality C1720777
DISO_to_DISO102img Seizures C0036572
DISO_to_ANAT101img Neurons C0027882
DISO_to_ANAT85img Brain C0006104
DISO_to_ANAT83img Brain C0006104
DISO_to_DISO83img chemically induced C0007994
DISO_to_DISO80img Memory Disorders C0025261
DISO_to_PHYS78img Functional Laterality C1720777
DISO_to_ANAT66img Amygdala C0002708
DISO_to_DISO66img Seizures C0036572
DISO_to_CHEM65img Anticonvulsants C0003286
DISO_to_ANAT62img Amygdala C0002708
DISO_to_ANAT61img Neurons C0027882
DISO_to_DISO56img COMPL POSTOP C0032787
DISO_to_PHYS54img Memory C0025260
DISO_to_DISO53img Memory Disorders C0025261
Genes (28)

Species:
human : 28
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanRTN457142reticulon 4
img GENERIF, Score=756, Pubmed Id: 15245492, UMLKSK CUI: C0014556
HumanACOT711332acyl-CoA thioesterase 7
img GENERIF, Score=717, Pubmed Id: 15592755, UMLKSK CUI: C0014556
HumanGABBR29568gamma-aminobutyric acid (GABA) B receptor, 2
img GENERIF, Score=1000, Pubmed Id: 14625043, UMLKSK CUI: C0014556
HumanLGI19211leucine-rich, glioma inactivated 1
img OMIM, Score=1000, UMLKSK CUI: C0014556
img GENERIF, Score=1000, Pubmed Id: 15079010, UMLKSK CUI: C0014556
HumanTP537157tumor protein p53
img GENERIF, Score=756, Pubmed Id: 17942278, UMLKSK CUI: C0014556
HumanSSTR26752somatostatin receptor 2
img GENERIF, Score=1000, Pubmed Id: 16254490, UMLKSK CUI: C0014556
HumanSLC1A26506solute carrier family 1 (glial high affinity glutamate transporter), member 2
img GENERIF, Score=679, Pubmed Id: 15246112, UMLKSK CUI: C0014556
HumanSCN1A6323sodium channel, voltage-gated, type I, alpha subunit
img GENERIF, Score=1000, Pubmed Id: 17565594, UMLKSK CUI: C0014556
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 12470703, UMLKSK CUI: C0014556
HumanRELN5649reelin
img GENERIF, Score=1000, Pubmed Id: 12122039, UMLKSK CUI: C0014556
HumanPRNP5621prion protein
img GENERIF, Score=923, Pubmed Id: 17092648, UMLKSK CUI: C0014556
img GENERIF, Score=923, Pubmed Id: 16580884, UMLKSK CUI: C0014556
img GENERIF, Score=923, Pubmed Id: 18549399, UMLKSK CUI: C0014556
HumanPDYN5173prodynorphin
img GENERIF, Score=1000, Pubmed Id: 18334734, UMLKSK CUI: C0014556
HumanNOS14842nitric oxide synthase 1 (neuronal)
img GENERIF, Score=1000, Pubmed Id: 12686399, UMLKSK CUI: C0014556
HumanMDM24193MDM2 oncogene, E3 ubiquitin protein ligase
img GENERIF, Score=717, Pubmed Id: 17942278, UMLKSK CUI: C0014556
HumanIL1B3553interleukin 1, beta
img GENERIF, Score=756, Pubmed Id: 14510824, UMLKSK CUI: C0014556
img GAD, Score=1000, Pubmed Id: 14510824, UMLKSK CUI: C0014556
img GENERIF, Score=1000, Pubmed Id: 18281914, UMLKSK CUI: C0014556
HumanHTR1A33505-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
img GENERIF, Score=884, Pubmed Id: 15111672, UMLKSK CUI: C0014556
HumanGRM12911glutamate receptor, metabotropic 1
img GENERIF, Score=923, Pubmed Id: 11951051, UMLKSK CUI: C0014556
HumanGRIA32892glutamate receptor, ionotropic, AMPA 3
img GENERIF, Score=1000, Pubmed Id: 15145077, UMLKSK CUI: C0014556
HumanGRIA22891glutamate receptor, ionotropic, AMPA 2
img GENERIF, Score=1000, Pubmed Id: 15145077, UMLKSK CUI: C0014556
HumanGRIA12890glutamate receptor, ionotropic, AMPA 1
img GENERIF, Score=1000, Pubmed Id: 15145077, UMLKSK CUI: C0014556
HumanGABRB32562gamma-aminobutyric acid (GABA) A receptor, beta 3
img GENERIF, Score=1000, Pubmed Id: 14503638, UMLKSK CUI: C0014556
HumanGABBR12550gamma-aminobutyric acid (GABA) B receptor, 1
img GENERIF, Score=1000, Pubmed Id: 14625043, UMLKSK CUI: C0014556
img GENERIF, Score=923, Pubmed Id: 14643764, UMLKSK CUI: C0014556
img GENERIF, Score=1000, Pubmed Id: 12115687, UMLKSK CUI: C0014556
img GENERIF, Score=1000, Pubmed Id: 15799783, UMLKSK CUI: C0014556
HumanEIF2S11965eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
img GENERIF, Score=1000, Pubmed Id: 12686399, UMLKSK CUI: C0014556
HumanDPYSL21808dihydropyrimidinase-like 2
img GENERIF, Score=923, Pubmed Id: 15672539, UMLKSK CUI: C0014556
HumanDFFB1677DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
img GENERIF, Score=756, Pubmed Id: 16121124, UMLKSK CUI: C0014556
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0014556Epilepsy, Temporal Lobe0self