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Details
Link-It Detail - Disease - Epilepsies, Partial
Debug Stats
  • ### Total Build Time: 126 ms 41.204 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 791 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 544 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 2.703 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.510 KB
  • CONCEPT_RELATIONSHIPS gt=105 ms Completed: 105 ms rowSize= 13.641 KB
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 20.354 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Epilepsies, Partial C0014547
Definition (1)
Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Epilepsy C0014544
Children (6)
img Epilepsy, Frontal Lobe C0085541
img Epilepsy, Complex Partial C0085417
img Epilepsy, Temporal Lobe C0014556
img Epilepsy, Rolandic C0376532
img Epilepsy, Partial, Sensory C0752322
img Epilepsy, Partial, Motor C0016399
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Epilepsy C0014544
Relationships (200)

Relation Types:
diso_​to_​anat : 11
diso_​to_​chem : 149
diso_​to_​diso : 37
diso_​to_​phen : 2
diso_​to_​phys : 1


Relationships:
none : 49
entry_​version_​of : 1
isa : 12
may_​treat : 137
replaces : 1
Page Size
Current 25
  Page 1 of 8
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM227img Anticonvulsants C0003286
DISO_to_CHEM221img Anticonvulsants C0003286
DISO_to_DISO119img Complication Aspects C1171258
DISO_to_DISO90img Epilepsy, Generalized C0014548
DISO_to_ANAT89img Cerebral Cortex C0007776
DISO_to_DISO84img Complication Aspects C1171258
DISO_to_DISO78img Seizures C0036572
DISO_to_ANAT73img Cerebral Cortex C0007776
DISO_to_ANAT72img Brain C0006104
DISO_to_ANAT66img Brain C0006104
DISO_to_PHEN53img genetic aspects C0017399
DISO_to_DISO51img Epilepsy, Generalized C0014548
DISO_to_CHEM49img 1-Pyrrolidineacetamide, 2-oxo- C0031977
DISO_to_CHEM45img Carbamazepine C0006949
DISO_to_DISO45img Seizures C0036572
DISO_to_CHEM40img 1-Pyrrolidineacetamide, 2-oxo- C0031977
DISO_to_PHEN40img genetic aspects C0017399
DISO_to_DISO36img Hamartoma C0018552
DISO_to_CHEM33img .GAMMA.-AMINOBUTYRIC ACID C0016904
DISO_to_CHEM30img Acetamides C0000968
DISO_to_CHEM29img Carbamazepine C0006949
DISO_to_CHEM27img .GAMMA.-AMINOBUTYRIC ACID C0016904
DISO_to_DISO27img 755-756 HAMARTOMAS C0018552
DISO_to_DISO27img Hypothalamic Diseases C0020655
DISO_to_DISO27img Status Epilepticus C0038220
Genes (33)

Species:
human : 33
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanRTN457142reticulon 4
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanCNTNAP226047contactin associated protein-like 2
img GENERIF, Score=1000, Pubmed Id: 16571880, UMLKSK CUI: C0014547
HumanACOT711332acyl-CoA thioesterase 7
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGABBR29568gamma-aminobutyric acid (GABA) B receptor, 2
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanLGI19211leucine-rich, glioma inactivated 1
img GENERIF, Score=861, Pubmed Id: 11810107, UMLKSK CUI: C0014547
img GENERIF, Score=1000, Pubmed Id: 16707245, UMLKSK CUI: C0014547
img GENERIF, Score=861, Pubmed Id: 12771268, UMLKSK CUI: C0014547
img GENERIF, Score=861, Pubmed Id: 15079010, UMLKSK CUI: C0014547
HumanTP537157tumor protein p53
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanSSTR26752somatostatin receptor 2
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanSLC1A26506solute carrier family 1 (glial high affinity glutamate transporter), member 2
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanSCN1A6323sodium channel, voltage-gated, type I, alpha subunit
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanRELN5649reelin
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanPRNP5621prion protein
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanPDYN5173prodynorphin
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanNOS14842nitric oxide synthase 1 (neuronal)
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanMDM24193MDM2 oncogene, E3 ubiquitin protein ligase
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanIL1B3553interleukin 1, beta
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanHTR1A33505-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGRM12911glutamate receptor, metabotropic 1
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGRIA32892glutamate receptor, ionotropic, AMPA 3
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGRIA22891glutamate receptor, ionotropic, AMPA 2
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGRIA12890glutamate receptor, ionotropic, AMPA 1
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGABRB32562gamma-aminobutyric acid (GABA) A receptor, beta 3
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanGABBR12550gamma-aminobutyric acid (GABA) B receptor, 1
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanEIF2S11965eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
INFERRED, Score=800, UMLKSK CUI: C0014547
HumanDPYSL21808dihydropyrimidinase-like 2
INFERRED, Score=800, UMLKSK CUI: C0014547
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0014547Epilepsies, Partial0self