Human | FIP1L1 | 81608 | factor interacting with PAPOLA and CPSF1 | FIP1L1-PDGFRA is a relatively infrequent but treatment-relevant mutation in primary eosinophilia that is indicative of an underlying systemic mastocytosis |
Human | IL25 | 64806 | interleukin 25 | Transgenic overexpression from humans into mice results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production |
Human | DCLRE1C | 64421 | DNA cross-link repair 1C | |
Human | CHIC2 | 26511 | cysteine-rich hydrophobic domain 2 | used fluorescence in situ hybridization to detect deletion of the CHIC2 locus at 4q12 as a surrogate for the FIP1L1-PDGFRA fusion and was observed in bone marrow cells for 3 of 5 patients with systemic mast cell disease associated with eosinophilia |
Human | TNFRSF10C | 8794 | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | These alterations in TRAIL receptor 3 expression might be involved in the molecular pathogenesis of Churg-Strauss syndrome eosinophilia |
Human | TP63 | 8626 | tumor protein p63 | This study demonstrated that sclerosing mucoepidermoid carcinomas with eosinophilia (SMECE) stain strongly positive for p63, which is a new marker for UBB/solid cell nests |
Human | IKBKG | 8517 | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | Leukocytosis with eosinophilia during stage 1 |
Human | STAT6 | 6778 | signal transducer and activator of transcription 6, interleukin-4 induced | Title:|Association:Y|Conclusion:We conclude that the human STAT6 gene is rather involved in the development of eosinophilia and changes in total IgE levels than contributing to the pathogenesis of asthma. |
Human | STAT3 | 6774 | signal transducer and activator of transcription 3 (acute-phase response factor) | |
Human | CCL17 | 6361 | chemokine (C-C motif) ligand 17 | TARC overexpression is associated with eosinophilia in T-cell lymphomas |
Human | RNASE3 | 6037 | ribonuclease, RNase A family, 3 | INFERRED, Score=800, UMLKSK CUI: C0014457 |
Human | RAG2 | 5897 | recombination activating gene 2 | |
Human | RAG1 | 5896 | recombination activating gene 1 | |
Human | PTGDS | 5730 | prostaglandin D2 synthase 21kDa (brain) | Pronounced eosinophilia and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice |
Human | PDGFRA | 5156 | platelet-derived growth factor receptor, alpha polypeptide | Sustained eosinophilia (greater than 1,500/cubic mm) for greater than 6 months |
Human | IL10 | 3586 | interleukin 10 | Title:|Association:Y|Conclusion:Not Found |
Human | IL5 | 3567 | interleukin 5 (colony-stimulating factor, eosinophil) | Inhaled IL-5 modulated eosinophil progenitor numbers in both the airways and bone marrow of asthmatics and induced local eosinophilia in non-asthmatics IL-5 overexpression is associated with eosinophilia in T-cell lymphomas Title:|Association:Not Found|Conclusion:Not Found |
Human | IL2RA | 3559 | interleukin 2 receptor, alpha | Serum soluble interleukin-2 receptor correlates with probable etiology and severity of disease in eosinophilia |
Human | GFI1 | 2672 | growth factor independent 1 transcription repressor | |
Human | ETV6 | 2120 | ets variant 6 | Chronic myelocytic leukemia with eosinophilia, t(9;12)(q34;p13), and ETV6-ABL gene rearrangement: case report and review of the literature |
Human | ELANE | 1991 | elastase, neutrophil expressed | |
Human | CCNT1 | 904 | cyclin T1 | INFERRED, Score=800, UMLKSK CUI: C0014457 |
Human | CASP10 | 843 | caspase 10, apoptosis-related cysteine peptidase | |
Human | CAPN3 | 825 | calpain 3, (p94) | Transient eosinophilia in first decade |
Human | FAS | 355 | Fas cell surface death receptor | |