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Details
Link-It Detail - Disease - Endocarditis
Debug Stats
  • ### Total Build Time: 60 ms 22.799 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.096 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 550 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 561 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 1.499 KB
  • CONCEPT_RELATIONSHIPS gt=46 ms Completed: 46 ms rowSize= 13.497 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 3.950 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Endocarditis C0014118
Definition (1)

Endocarditis is an inflammation of your heart's inner lining. The most common type, bacterial endocarditis, occurs when germs enter your heart. These germs come through your bloodstream from another part of your body, often your mouth. Bacterial endocarditis can damage your heart valves. If untreated, it can be life-threatening. It is rare in healthy hearts.

Risk factors include having

  • An abnormal or damaged heart valve
  • A severe case of mitral valve prolapse
  • An artificial heart valve
  • Certain heart defects

If you have a high risk of bacterial endocarditis, your doctor might prescribe antibiotics before dental work and certain types of surgery.

Early treatment can help you avoid complications. Symptoms you might notice include fever, shortness of breath, fluid buildup in your arms or legs, tiny red spots on your skin and weight loss. Treatment usually involves high-dose antibiotics.

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Heart Diseases C0018799
Children (1)
img Endocarditis, Bacterial C0014121
Ancestral Roots
RootRoot Plus OneDepthParent
img Cardiovascular Diseases C0007222img Heart Diseases C00187993img Heart Diseases C0018799
Relationships (93)

Relation Types:
diso_​to_​anat : 12
diso_​to_​chem : 27
diso_​to_​diso : 54


Relationships:
none : 45
clinically_​similar : 3
is_​associated_​anatomic_​site_​of : 4
isa : 13
may_​treat : 25
parent_​is_​cdrh : 1
permuted_​term_​of : 1
related_​to : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO263img Complication Aspects C1171258
DISO_to_DISO102img Prosthesis-Related Infection C0085073
DISO_to_DISO99img Complication Aspects C1171258
DISO_to_ANAT86img Aortic Valve C0003501
DISO_to_DISO84img Heart Valve Diseases C0018824
DISO_to_ANAT81img Mitral Valve C0026264
DISO_to_CHEM59img Anti-Bacterial Agents C0279516
DISO_to_DISO46img Candidiasis C0006840
DISO_to_DISO44img Prosthesis-Related Infection C0085073
DISO_to_DISO44img Staphylococcal Infections C0038160
DISO_to_DISO39img Candidiasis C0006840
DISO_to_DISO36img Thrombosis C0040053
DISO_to_ANAT34img Aortic Valve C0003501
DISO_to_DISO34img Heart Valve Diseases C0018824
DISO_to_ANAT32img Tricuspid Valve C0040960
DISO_to_DISO31img Mitral Valve Insufficiency C0026266
DISO_to_ANAT28img Mitral Valve C0026264
DISO_to_DISO25img ASPERGILLOSIS C0004030
DISO_to_DISO25img Aortic Valve Insufficiency C0003504
DISO_to_DISO24img Abscess C0000833
DISO_to_DISO24img Lupus Erythematosus, Systemic C0024141
DISO_to_ANAT23img In Blood C0005768
DISO_to_DISO22img BACT INFECT GRAM POS C0085426
DISO_to_DISO21img Bacterial Endocarditis C0014121
DISO_to_DISO21img Mycoses C0026946
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanPRKAR1A5573protein kinase, cAMP-dependent, regulatory, type I, alpha
INFERRED, Score=800, UMLKSK CUI: C0014118
HumanSMAD44089SMAD family member 4
INFERRED, Score=800, UMLKSK CUI: C0014118
HumanSMAD34088SMAD family member 3
INFERRED, Score=800, UMLKSK CUI: C0014118
HumanLAMA33909laminin, alpha 3
INFERRED, Score=800, UMLKSK CUI: C0014118
HumanJUN3725jun proto-oncogene
INFERRED, Score=800, UMLKSK CUI: C0014118
HumanIL1A3552interleukin 1, alpha
INFERRED, Score=800, UMLKSK CUI: C0014118
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0014118Endocarditis0self