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Details
Link-It Detail - Disease - Encephalomalacia
Debug Stats
  • ### Total Build Time: 22 ms 16.709 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 790 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 550 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 567 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.516 KB
  • CONCEPT_RELATIONSHIPS gt=5 ms Completed: 5 ms rowSize= 7.071 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 4.576 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Encephalomalacia C0014068
Definition (1)
Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Brain Diseases C0006111
Children (1)
img Leukomalacia, Periventricular C0023529
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076824img Brain Diseases C0006111
Relationships (16)

Relation Types:
diso_​to_​anat : 4
diso_​to_​diso : 12


Relationships:
none : 8
is_​associated_​anatomic_​site_​of : 2
isa : 5
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO4img Complication Aspects C1171258
DISO_to_DISO4img chemically induced C0007994
DISO_to_ANAT3img Brain C0006104
DISO_to_ANAT3img Cerebral Cortex C0007776
DISO_to_DISO3img BOVINE DIS C0007453
DISO_to_DISO3img Complication Aspects C1171258
DISO_to_DISO3img Fetal Death C0015927
DISO_to_DISO3img chemically induced C0007994
DISO_to_ANATis_associated_anatomic_site_ofimg Central Nervous System C0927232
DISO_to_ANATis_associated_anatomic_site_ofimg Nervous System C0027763
DISO_to_DISOisaimg Avian encephalomalacia C0268685
DISO_to_DISOpermuted_term_ofimg Cerebromalacia C0014068
DISO_to_DISOisaimg Chastek paralysis C0268667
DISO_to_DISOisaimg ENCEPH MULTICYSTIC C0393992
DISO_to_DISOisaimg Encephalomalacia, Periventricular C0023529
DISO_to_DISOisaimg Ruminant polioencephalomalacia C0270700
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanTREX111277three prime repair exonuclease 1
INFERRED, Score=800, UMLKSK CUI: C0014068
HumanSLC1A26506solute carrier family 1 (glial high affinity glutamate transporter), member 2
INFERRED, Score=800, UMLKSK CUI: C0014068
HumanPC5091pyruvate carboxylase
INFERRED, Score=800, UMLKSK CUI: C0014068
HumanMYT14661myelin transcription factor 1
INFERRED, Score=800, UMLKSK CUI: C0014068
HumanIL183606interleukin 18 (interferon-gamma-inducing factor)
INFERRED, Score=800, UMLKSK CUI: C0014068
HumanIL23558interleukin 2
INFERRED, Score=800, UMLKSK CUI: C0014068
HumanEPO2056erythropoietin
INFERRED, Score=800, UMLKSK CUI: C0014068
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0014068Encephalomalacia0self