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Details
Link-It Detail - Disease - Dysgerminoma
Debug Stats
  • ### Total Build Time: 30 ms 24.377 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 701 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 545 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.494 KB
  • CONCEPT_RELATIONSHIPS gt=13 ms Completed: 13 ms rowSize= 12.005 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 7.982 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dysgerminoma C0013377
Definition (1)
A malignant germ cell tumor characterized by the presence of a monotonous primitive germ cell population. The neoplastic cells form aggregates and have an abundant pale cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily in the ovaries, but can occur both primarily and secondarily at other sites, particularly the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis is related to the tumor stage.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Germinoma C0206660
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Germinoma C0206660
Relationships (25)

Relation Types:
diso_​to_​anat : 7
diso_​to_​diso : 16
diso_​to_​phen : 2


Relationships:
none : 11
is_​abnormal_​cell_​of_​disease : 4
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
isa : 1
may_​be_​molecular_​abnormality_​of_​disease : 2
permuted_​term_​of : 1
used_​for : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO59img Ovarian Neoplasms C0919267
DISO_to_DISO34img Ovarian Neoplasms C0919267
DISO_to_PHEN20img genetic aspects C0017399
DISO_to_DISO19img Gonadoblastoma C0206661
DISO_to_DISO14img Gonadal Dysgenesis, 46,XY C0018054
DISO_to_DISO12img Complication Aspects C1171258
DISO_to_DISO9img Complication Aspects C1171258
DISO_to_PHEN9img genetic aspects C0017399
DISO_to_DISO8img MULTIPLE PRIMARY NEOPL C0027663
DISO_to_DISO4img GBY C0206661
DISO_to_DISO4img Testicular Neoplasms C0039590
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Germ Cells C0017471
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Germinal Layer C1708239
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Germ Cell C1708878
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Primitive Germ Cell C1514071
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Germ Cell C1513971
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Sex Cord-Stromal Cell C1514083
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg C-KIT Mutation C1511353
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg C-KIT Tyrosine Kinase Protein Overexpression C1511355
DISO_to_DISOis_finding_of_diseaseimg Chronic Inflammatory Infiltrate C1333036
DISO_to_DISOpermuted_term_ofimg DYSGERMINOMA, MALIGNANT C0013377
DISO_to_DISOisaimg Dysgerminoma of Ovary C0346185
DISO_to_DISOis_finding_of_diseaseimg Fibrous Septa Present C1708055
DISO_to_DISOused_forimg Germ cell tumor C0205851
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanSRY6736sex determining region Y
img NCI, Score=801, Pubmed Id: 12165453, UMLKSK CUI: C0013377
img NCI, Score=801, Pubmed Id: 12165453, UMLKSK CUI: C0013377
img NCI, Score=801, Pubmed Id: 10459352, UMLKSK CUI: C0013377
img NCI, Score=801, Pubmed Id: 12165453, UMLKSK CUI: C0013377
HumanSPINK16690serine peptidase inhibitor, Kazal type 1
img NCI, Score=801, Pubmed Id: 9887252, UMLKSK CUI: C0013377
HumanPTEN5728phosphatase and tensin homolog
img GENERIF, Score=1000, Pubmed Id: 18594467, UMLKSK CUI: C0013377
HumanLDHA3939lactate dehydrogenase A
img NCI, Score=801, Pubmed Id: 3405571, UMLKSK CUI: C0013377
HumanCYP27B11594cytochrome P450, family 27, subfamily B, polypeptide 1
img GENERIF, Score=1000, Pubmed Id: 15331405, UMLKSK CUI: C0013377
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0013377Dysgerminoma0self