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Details
Link-It Detail - Disease - Diabetic Retinopathy
Debug Stats
  • ### Total Build Time: 152 ms 66.624 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 338 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 368 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 991 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 5.330 KB
  • CONCEPT_RELATIONSHIPS gt=118 ms Completed: 118 ms rowSize= 14.576 KB
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 43.688 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.154 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Diabetic Retinopathy C0011884
Definition (1)
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Retinal Diseases C0035309
img Diabetic Angiopathies C0011875
Ancestral Roots
RootRoot Plus OneDepthParent
img Eye Diseases C0015397img Retinal Diseases C00353093img Retinal Diseases C0035309
img Endocrine System Diseases C0014130img Diabetes Mellitus C00118495img Diabetic Angiopathies C0011875
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255177img Diabetic Angiopathies C0011875
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Diabetic Angiopathies C0011875
Relationships (143)

Relation Types:
diso_​to_​anat : 23
diso_​to_​chem : 33
diso_​to_​diso : 72
diso_​to_​gene : 3
diso_​to_​phen : 2
diso_​to_​phys : 10


Relationships:
none : 114
associated_​with : 1
clinically_​similar : 10
gene_​associated_​with_​disease : 2
is_​associated_​anatomic_​site_​of : 4
isa : 11
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO608img Macular Edema C0271051
DISO_to_DISO433img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO379img Complication Aspects C1171258
DISO_to_ANAT293img Retina C0035298
DISO_to_DISO289img Macular Edema C0271051
DISO_to_DISO265img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO258img Complication Aspects C1171258
DISO_to_ANAT246img In Blood C0005768
DISO_to_DISO226img Diabetes Mellitus, Insulin-Dependent C0011854
DISO_to_CHEM196img ANGIOGENESIS INHIB C0596087
DISO_to_PHEN187img genetic aspects C0017399
DISO_to_ANAT168img Retina C0035298
DISO_to_DISO168img Diabetes Mellitus, Insulin-Dependent C0011854
DISO_to_ANAT167img Retinal Vessels C0035330
DISO_to_CHEM162img Antibodies, Monoclonal C0003250
DISO_to_ANAT158img In Blood C0005768
DISO_to_CHEM157img Vascular Endothelial Growth Factor A C0078058
DISO_to_DISO154img DIABETES MELLITUS EXPER C0011853
DISO_to_CHEM136img 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione C0040866
DISO_to_CHEM134img GLUCOCORTICOIDS C0017710
DISO_to_ANAT121img Vitreous Body C0042905
DISO_to_CHEM105img 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione C0040866
DISO_to_CHEM105img Triamcinolone Acetonide C0040866
DISO_to_PHEN101img genetic aspects C0017399
DISO_to_CHEM98img GLUCOCORTICOIDS C0017710
Genes (30)

Species:
human : 30
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSUMO4387082small ubiquitin-like modifier 4
img GENERIF, Score=1000, Pubmed Id: 17926234, UMLKSK CUI: C0011884
HumanAKR1B1057016aldo-keto reductase family 1, member B10 (aldose reductase)
img GENERIF, Score=1000, Pubmed Id: 15745835, UMLKSK CUI: C0011884
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=1000, Pubmed Id: 15248834, UMLKSK CUI: C0011884
HumanB4GALT28704UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
img GENERIF, Score=1000, Pubmed Id: 15504978, UMLKSK CUI: C0011884
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 16202216, UMLKSK CUI: C0011884
img GAD, Score=1000, Pubmed Id: 11978667, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 18363167, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 17121786, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 17716775, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 15963467, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 17470563, UMLKSK CUI: C0011884
img GENERIF, Score=913, Pubmed Id: 18053608, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 16514669, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 17622743, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 18441306, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 16636650, UMLKSK CUI: C0011884
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img GENERIF, Score=901, Pubmed Id: 11914750, UMLKSK CUI: C0011884
img GENERIF, Score=901, Pubmed Id: 15899948, UMLKSK CUI: C0011884
HumanVCAM17412vascular cell adhesion molecule 1
img GENERIF, Score=861, Pubmed Id: 15666579, UMLKSK CUI: C0011884
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 18398712, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 15504978, UMLKSK CUI: C0011884
HumanTIMP37078TIMP metallopeptidase inhibitor 3
img GENERIF, Score=1000, Pubmed Id: 17676308, UMLKSK CUI: C0011884
HumanSST6750somatostatin
img GENERIF, Score=1000, Pubmed Id: 17704349, UMLKSK CUI: C0011884
HumanSOD26648superoxide dismutase 2, mitochondrial
img GENERIF, Score=1000, Pubmed Id: 18057537, UMLKSK CUI: C0011884
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=1000, Pubmed Id: 18077048, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 11928067, UMLKSK CUI: C0011884
HumanSERPINF15176serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
img GENERIF, Score=1000, Pubmed Id: 17658465, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 18523656, UMLKSK CUI: C0011884
img GENERIF, Score=901, Pubmed Id: 16797605, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 17213275, UMLKSK CUI: C0011884
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
img GENERIF, Score=1000, Pubmed Id: 16416371, UMLKSK CUI: C0011884
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GENERIF, Score=1000, Pubmed Id: 12605344, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 18079690, UMLKSK CUI: C0011884
HumanMTHFR4524methylenetetrahydrofolate reductase (NAD(P)H)
img GENERIF, Score=1000, Pubmed Id: 12673582, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 12766148, UMLKSK CUI: C0011884
HumanITGA23673integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
img GENERIF, Score=1000, Pubmed Id: 12540964, UMLKSK CUI: C0011884
img GAD, Score=1000, Pubmed Id: 10688808, UMLKSK CUI: C0011884
HumanIGF13479insulin-like growth factor 1 (somatomedin C)
img GENERIF, Score=1000, Pubmed Id: 17851271, UMLKSK CUI: C0011884
img GENERIF, Score=1000, Pubmed Id: 16873705, UMLKSK CUI: C0011884
HumanICAM13383intercellular adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 12027924, UMLKSK CUI: C0011884
HumanTNC3371tenascin C
img GENERIF, Score=1000, Pubmed Id: 12351514, UMLKSK CUI: C0011884
HumanHP3240haptoglobin
img GENERIF, Score=1000, Pubmed Id: 17275123, UMLKSK CUI: C0011884
HumanFABP22169fatty acid binding protein 2, intestinal
img GENERIF, Score=1000, Pubmed Id: 14605999, UMLKSK CUI: C0011884
HumanENG2022endoglin
img GENERIF, Score=1000, Pubmed Id: 16202216, UMLKSK CUI: C0011884
HumanEDN11906endothelin 1
img GENERIF, Score=1000, Pubmed Id: 18806884, UMLKSK CUI: C0011884
HumanACE1636angiotensin I converting enzyme
img GAD, Score=1000, Pubmed Id: 11106834, UMLKSK CUI: C0011884
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0011884Diabetic Retinopathy0self