Mouse | LY6D | 8581 | lymphocyte antigen 6 complex, locus D | A cytotoxin-armed antibody reactive with one of these drug-induced surface proteins, the LY6D/E48 antigen, originally identified as the target of a monoclonal antibody reactive with squamous cell carcinomas, caused complete regression of colorectal tumor xenografts in mice treated with CPT-11, whereas either agent alone was less effective. |
Mouse | EPHA2 | 1969 | EPH receptor A2 | Treatment of established murine CT26 colorectal tumors with Ab20 reduced EphA2 protein levels to approximately 12% of control tumor levels, yet had no effect on tumor growth. |
Human | MUC5B | 727897 | mucin 5B, oligomeric mucus/gel-forming | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | BCL2L15 | 440603 | BCL2-like 15 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | MIR137 | 406928 | microRNA 137 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | AGRN | 375790 | agrin | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | ENPP7 | 339221 | ectonucleotide pyrophosphatase/phosphodiesterase 7 | Click here to display 4 evidence detail records. |
Human | SPATA13 | 221178 | spermatogenesis associated 13 | These results suggest that similar to Asef, Asef2 plays an important role in cell migration, and that Asef2 activated by truncated mutant APC is required for aberrant migration of colorectal tumor cells |
Human | PAOX | 196743 | polyamine oxidase (exo-N4-amino) | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | NEWENTRY | 192343 | Record to support submission of GeneRIFs for a gene not in Gene (human; man). | Topo IIalpha interacts with beta-catenin/T-cell factor-4 as a novel transcriptional co-activator in colorectal neoplasms [beta-catenin] |
Human | DACT2 | 168002 | dishevelled-binding antagonist of beta-catenin 2 | Nuclear beta-catenin was more frequently expressed in non-polypoid growth low grade colorectal neoplasms than in polypoid growth neoplasms |
Human | CLDN23 | 137075 | claudin 23 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | PPARGC1B | 133522 | peroxisome proliferator-activated receptor gamma, coactivator 1 beta | Upregulation of PGC-1alpha and PGC-1beta in the colorectal tumor cells can be part of an adaptation mechanism to help overcome the severe consequences of mtDNA mutations on oxidative phosphorylation |
Human | MINA | 84864 | MYC induced nuclear antigen | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | TUBA1C | 84790 | tubulin, alpha 1c | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | ANTXR1 | 84168 | anthrax toxin receptor 1 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | REG4 | 83998 | regenerating islet-derived family, member 4 | Click here to display 4 evidence detail records. |
Human | SOX7 | 83595 | SRY (sex determining region Y)-box 7 | On the other hand, SOX7 mRNA was significantly down-regulated in 7 out of 18 cases of primary colorectal tumors, in 4 out of 9 cases of primary breast cancer, in 4 out of 14 cases of primary kidney tumors, and also in some cases of primary lung and prostate cancer. |
Human | TNKS2 | 80351 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | CDCP1 | 64866 | CUB domain containing protein 1 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | RHOU | 58480 | ras homolog family member U | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | MUC3B | 57876 | mucin 3B, cell surface associated | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | S100A14 | 57402 | S100 calcium binding protein A14 | INFERRED, Score=800, UMLKSK CUI: C0009404 |
Human | CTNNBIP1 | 56998 | catenin, beta interacting protein 1 | Click here to display 6 evidence detail records. |
Human | CHFR | 55743 | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | INFERRED, Score=800, UMLKSK CUI: C0009404 |