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Details
Link-It Detail - Disease - Cluster Headache
Debug Stats
  • ### Total Build Time: 56 ms 28.551 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 658 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 569 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.534 KB
  • CONCEPT_RELATIONSHIPS gt=27 ms Completed: 27 ms rowSize= 12.947 KB
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 11.180 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cluster Headache C0009088
Definition (1)
A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Trigeminal Autonomic Cephalalgias C1565172
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076827img Trigeminal Autonomic Cephalalgias C1565172
Relationships (75)

Relation Types:
diso_​to_​anat : 11
diso_​to_​chem : 46
diso_​to_​diso : 16
diso_​to_​phen : 2


Relationships:
none : 32
isa : 3
mapped_​to : 2
may_​treat : 37
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO41img Complication Aspects C1171258
DISO_to_DISO34img Complication Aspects C1171258
DISO_to_DISO28img Migraine Disorders C0149931
DISO_to_PHEN24img genetic aspects C0017399
DISO_to_PHEN15img genetic aspects C0017399
DISO_to_ANAT14img Hypothalamic Region, Posterior C0020670
DISO_to_CHEM13img Serotonin Agonists C0162757
DISO_to_CHEM13img Tryptamines C0041248
DISO_to_DISO13img Autonomic Nervous System Diseases C1145628
DISO_to_ANAT12img Hypothalamic structure C0020663
DISO_to_ANAT11img In Blood C0005768
DISO_to_CHEM11img 1H-Indole-5-methanesulfonamide, 3-(2-(dimethylamino)ethyl)-N-methyl- C0075632
DISO_to_DISO11img chemically induced C0007994
DISO_to_ANAT10img Hypothalamic structure C0020663
DISO_to_ANAT10img Trigeminal Nerve C0040996
DISO_to_CHEM9img Analgesics C0002771
DISO_to_ANAT8img Brain C0006104
DISO_to_ANAT8img Trigeminal Nerve C0040996
DISO_to_CHEM8img Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)- C0042523
DISO_to_CHEM8img Fructose C0016745
DISO_to_CHEM8img Serotonin Agonists C0162757
DISO_to_DISO8img Trigeminal Neuralgia C0040997
DISO_to_ANAT7img Ganglia, Parasympathetic C0017069
DISO_to_DISO7img Headache C0018681
DISO_to_DISO7img Pain C0030193
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanCLOCK9575clock circadian regulator
img GENERIF, Score=1000, Pubmed Id: 18283403, UMLKSK CUI: C0009088
HumanVCAM17412vascular cell adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 18197885, UMLKSK CUI: C0009088
HumanSELE6401selectin E
img GENERIF, Score=734, Pubmed Id: 18197885, UMLKSK CUI: C0009088
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GENERIF, Score=734, Pubmed Id: 12421162, UMLKSK CUI: C0009088
HumanNOS24843nitric oxide synthase 2, inducible
img GENERIF, Score=734, Pubmed Id: 12421162, UMLKSK CUI: C0009088
HumanNOS14842nitric oxide synthase 1 (neuronal)
img GENERIF, Score=734, Pubmed Id: 12421162, UMLKSK CUI: C0009088
HumanHCRTR23062hypocretin (orexin) receptor 2
img GAD, Score=1000, Pubmed Id: 15477554, UMLKSK CUI: C0009088
img GENERIF, Score=1000, Pubmed Id: 17883525, UMLKSK CUI: C0009088
img GENERIF, Score=1000, Pubmed Id: 17563843, UMLKSK CUI: C0009088
img GENERIF, Score=1000, Pubmed Id: 15477554, UMLKSK CUI: C0009088
HumanGNB32784guanine nucleotide binding protein (G protein), beta polypeptide 3
img GENERIF, Score=694, Pubmed Id: 17361120, UMLKSK CUI: C0009088
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0009088Cluster Headache0self