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Details
Link-It Detail - Disease - Choriocarcinoma
Debug Stats
  • ### Total Build Time: 543 ms 71.890 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 328 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 589 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=17 ms Completed: 17 ms rowSize= 1.409 KB
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 1,023 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=48 ms Completed: 48 ms rowSize= 9.264 KB
  • CONCEPT_RELATIONSHIPS gt=345 ms Completed: 345 ms rowSize= 14.146 KB
  • CONCEPT_GENES gt=108 ms Completed: 108 ms rowSize= 43.817 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Choriocarcinoma C0008497
Definition (1)
A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
Semantic Types (1)
Neoplastic Process (T191)
Parents (3)
img Gestational Trophoblastic Disease C1135868
img Trophoblastic Neoplasms C0041182
img Adenocarcinoma C0001418
Children (2)
img Choriocarcinoma, Non-gestational C1135873
img Trophoblastic Tumor, Placental Site C0206666
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Gestational Trophoblastic Disease C1135868
img Neoplasms C0027651img Pregnancy Complications, Neoplastic C00329665img Gestational Trophoblastic Disease C1135868
img Female Urogenital Diseases and Pregnancy Complications C1720765img Pregnancy Complications C00329626img Gestational Trophoblastic Disease C1135868
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Trophoblastic Neoplasms C0041182
img Neoplasms C0027651img Pregnancy Complications, Neoplastic C00329664img Trophoblastic Neoplasms C0041182
img Female Urogenital Diseases and Pregnancy Complications C1720765img Pregnancy Complications C00329625img Trophoblastic Neoplasms C0041182
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Adenocarcinoma C0001418
Relationships (76)

Relation Types:
diso_​to_​anat : 12
diso_​to_​chem : 12
diso_​to_​diso : 47
diso_​to_​phen : 2
diso_​to_​phys : 3


Relationships:
none : 47
is_​abnormal_​cell_​of_​disease : 5
is_​finding_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
isa : 10
may_​be_​finding_​of_​disease : 2
may_​treat : 7
use : 2
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO150img Uterine Neoplasms C0042138
DISO_to_DISO136img NEOPL UTERINE C0042138
DISO_to_PHEN45img genetic aspects C0017399
DISO_to_PHEN39img genetic aspects C0017399
DISO_to_DISO36img Complication Aspects C1171258
DISO_to_DISO33img Complication Aspects C1171258
DISO_to_DISO33img Testicular Neoplasms C0039590
DISO_to_DISO32img Lung Neoplasms C0024121
DISO_to_DISO28img Hydatidiform Mole C0020217
DISO_to_DISO27img Testicular Neoplasms C0039590
DISO_to_DISO25img Lung Neoplasms C0024121
DISO_to_DISO24img Hydatidiform Mole C0020217
DISO_to_ANAT22img In Blood C0005768
DISO_to_DISO22img Pregnancy Complications, Neoplastic C0032966
DISO_to_ANAT21img Placenta C0032043
DISO_to_ANAT21img Trophoblasts C0041178
DISO_to_DISO21img COMPL NEOPL PREGN C0032966
DISO_to_ANAT20img Trophoblasts C0041178
DISO_to_ANAT19img Placenta C0032043
DISO_to_DISO19img Gestational trophoblastic disease C2931618
DISO_to_DISO18img Brain Neoplasms C0006118
DISO_to_DISO17img Ovarian Neoplasms C0919267
DISO_to_ANAT16img In Blood C0005768
DISO_to_CHEM16img Chorionic Gonadotropin C0018062
DISO_to_DISO14img Stomach Neoplasms C0038356
Genes (163)

Species:
human : 163
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanERVK7449619
img NCI, Score=801, Pubmed Id: 9524581, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 9474889, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 8909261, UMLKSK CUI: C0008497
HumanNCR3259197natural cytotoxicity triggering receptor 3
img NCI, Score=801, Pubmed Id: 11137207, UMLKSK CUI: C0008497
HumanCHCHD1118487coiled-coil-helix-coiled-coil-helix domain containing 1
img NCI, Score=801, Pubmed Id: 15177562, UMLKSK CUI: C0008497
HumanKISS1R84634KISS1 receptor
img NCI, Score=801, Pubmed Id: 12414911, UMLKSK CUI: C0008497
HumanHOPX84525HOP homeobox
img NCI, Score=801, Pubmed Id: 14614883, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 12573257, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 12573257, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 12573257, UMLKSK CUI: C0008497
HumanMCM884515minichromosome maintenance complex component 8
img NCI, Score=801, Pubmed Id: 12771218, UMLKSK CUI: C0008497
HumanINHBE83729inhibin, beta E
img NCI, Score=801, Pubmed Id: 9591212, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 10775170, UMLKSK CUI: C0008497
HumanNCAPG64151non-SMC condensin I complex, subunit G
img NCI, Score=801, Pubmed Id: 380508, UMLKSK CUI: C0008497
HumanERVK664006
img NCI, Score=801, Pubmed Id: 9524581, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 8909261, UMLKSK CUI: C0008497
HumanMMP2656547matrix metallopeptidase 26
img NCI, Score=801, Pubmed Id: 12087081, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 12087081, UMLKSK CUI: C0008497
HumanERAP151752endoplasmic reticulum aminopeptidase 1
img NCI, Score=801, Pubmed Id: 14691298, UMLKSK CUI: C0008497
HumanCD24451744CD244 molecule, natural killer cell receptor 2B4
img NCI, Score=801, Pubmed Id: 11137207, UMLKSK CUI: C0008497
HumanERVWE130816
img NCI, Score=801, Pubmed Id: 15888734, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 14580378, UMLKSK CUI: C0008497
HumanBRMS125855breast cancer metastasis suppressor 1
img NCI, Score=801, Pubmed Id: 12414911, UMLKSK CUI: C0008497
HumanPEG1023089paternally expressed 10
img NCI, Score=801, Pubmed Id: 12620933, UMLKSK CUI: C0008497
HumanKLRK122914killer cell lectin-like receptor subfamily K, member 1
img NCI, Score=801, Pubmed Id: 11137207, UMLKSK CUI: C0008497
HumanMGAT4A11320mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
img NCI, Score=801, Pubmed Id: 10463590, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 10571021, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 10571021, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 10463590, UMLKSK CUI: C0008497
HumanHTATIP210553HIV-1 Tat interactive protein 2, 30kDa
img NCI, Score=801, Pubmed Id: 3265633, UMLKSK CUI: C0008497
HumanNFE2L39603nuclear factor, erythroid 2-like 3
img NCI, Score=801, Pubmed Id: 15388789, UMLKSK CUI: C0008497
HumanGDF159518growth differentiation factor 15
img NCI, Score=801, Pubmed Id: 15297175, UMLKSK CUI: C0008497
HumanPTTG19232pituitary tumor-transforming 1
img NCI, Score=801, Pubmed Id: 12213878, UMLKSK CUI: C0008497
HumanSGCE8910sarcoglycan, epsilon
img NCI, Score=801, Pubmed Id: 12620933, UMLKSK CUI: C0008497
HumanENDOU8909endonuclease, polyU-specific
img NCI, Score=801, Pubmed Id: 8543850, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 8543850, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 2446567, UMLKSK CUI: C0008497
HumanSQSTM18878sequestosome 1
img NCI, Score=801, Pubmed Id: 8390539, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 8390539, UMLKSK CUI: C0008497
HumanDLEU28847deleted in lymphocytic leukemia 2 (non-protein coding)
img NCI, Score=801, Pubmed Id: 6443577, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 3054885, UMLKSK CUI: C0008497
img NCI, Score=801, Pubmed Id: 3054885, UMLKSK CUI: C0008497
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0008497Choriocarcinoma0self