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Details
Link-It Detail - Disease - Hydatidiform Mole, Invasive
Debug Stats
  • ### Total Build Time: 21 ms 27.352 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 405 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 502 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 553 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 4.084 KB
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 9.051 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 11.412 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Hydatidiform Mole, Invasive C0008493
CHORIOADENOMA DESTRUENS
Definition (1)
A uterine tumor derived from persistent gestational TROPHOBLASTS, most likely after a molar pregnancy (HYDATIDIFORM MOLE). Invasive hyadatiform mole develops in about 15% of patients after evacuation of a complete mole and less frequently after other types of gestation. It may perforate the MYOMETRIUM and erode uterine vessels causing hemorrhage.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Hydatidiform Mole C0020217
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276527img Hydatidiform Mole C0020217
img Female Urogenital Diseases and Pregnancy Complications C1720765img Pregnancy Complications C00329627img Hydatidiform Mole C0020217
img Neoplasms C0027651img Pregnancy Complications, Neoplastic C00329666img Hydatidiform Mole C0020217
Relationships (17)

Relation Types:
diso_​to_​anat : 7
diso_​to_​diso : 9
diso_​to_​phen : 1


Relationships:
none : 4
associated_​with : 2
is_​abnormal_​cell_​of_​disease : 2
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 3
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
location_​of : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO11img NEOPL UTERINE C0042138
DISO_to_DISO10img NEOPL UTERINE C0042138
DISO_to_DISO5img Choriocarcinoma C0008497
DISO_to_PHEN5img genetic aspects C0017399
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Female Reproductive System C0700038
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Round Germ Cell with Glycogen-Rich Cytoplasm and Round Nucleus C1881590
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Trophoblastic Cell C1514116
DISO_to_ANATlocation_ofimg Placenta C0032043
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATlocation_ofimg Uterus C0042149
DISO_to_DISOassociated_withimg Abnormal Pregnancy C0278056
DISO_to_DISOassociated_withimg CHORIOADENOMA DESTRUENS C0008493
DISO_to_DISOis_finding_of_diseaseimg Hydropic Villous Change C1334065
DISO_to_DISOis_finding_of_diseaseimg Invasive Lesion C1334278
DISO_to_DISOis_not_finding_of_diseaseimg Mixture of Germ Cell Neoplastic Components Present C1711227
DISO_to_DISOis_finding_of_diseaseimg Pregnancy Complications C0032962
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanRFC25982replication factor C (activator 1) 2, 40kDa
img NCI, Score=801, Pubmed Id: 14960244, UMLKSK CUI: C0008493
HumanRASA15921RAS p21 protein activator (GTPase activating protein) 1
img NCI, Score=801, Pubmed Id: 7747802, UMLKSK CUI: C0008493
HumanPZP5858pregnancy-zone protein
img NCI, Score=801, Pubmed Id: 7882729, UMLKSK CUI: C0008493
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 11963831, UMLKSK CUI: C0008493
HumanIGFBP13484insulin-like growth factor binding protein 1
img NCI, Score=801, Pubmed Id: 6318674, UMLKSK CUI: C0008493
img NCI, Score=801, Pubmed Id: 6318674, UMLKSK CUI: C0008493
HumanGPC12817glypican 1
img NCI, Score=801, Pubmed Id: 10629564, UMLKSK CUI: C0008493
HumanERV32086endogenous retrovirus group 3, member 1
img NCI, Score=801, Pubmed Id: 3346101, UMLKSK CUI: C0008493
HumanASCL2430achaete-scute complex homolog 2 (Drosophila)
img GENERIF, Score=1000, Pubmed Id: 17165436, UMLKSK CUI: C0008493
HumanA2M2alpha-2-macroglobulin
img NCI, Score=801, Pubmed Id: 6165464, UMLKSK CUI: C0008493
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0008493Hydatidiform Mole, Invasive0self