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Details
Link-It Detail - Disease - Cholesteatoma
Debug Stats
  • ### Total Build Time: 31 ms 31.062 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 450 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 545 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 563 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.505 KB
  • CONCEPT_RELATIONSHIPS gt=12 ms Completed: 12 ms rowSize= 12.334 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 14.027 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cholesteatoma C0008373
Definition (1)
A non-neoplastic mass of keratin-producing squamous EPITHELIUM, frequently occurring in the MENINGES; bones of the skull, and most commonly in the MIDDLE EAR and MASTOID region. Cholesteatoma can be congenital or acquired. Cholesteatoma is not a tumor nor is it associated with high CHOLESTEROL.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Keratosis C0022593
Children (1)
img Cholesteatoma, Middle Ear C0155490
Ancestral Roots
RootRoot Plus OneDepthParent
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Keratosis C0022593
Relationships (28)

Relation Types:
diso_​to_​anat : 11
diso_​to_​diso : 17


Relationships:
none : 16
classifies : 1
is_​associated_​anatomic_​site_​of : 1
isa : 4
mapped_​to : 6
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT26img Ear Canal C0013444
DISO_to_DISO25img Complication Aspects C1171258
DISO_to_ANAT22img Ear Canal C0013444
DISO_to_DISO20img Ear Diseases C0013447
DISO_to_DISO17img Complication Aspects C1171258
DISO_to_ANAT15img Mastoid C0446908
DISO_to_ANAT11img Mastoid C0446908
DISO_to_ANAT9img Petrous Bone C0031266
DISO_to_ANAT9img Temporal Bone C0039484
DISO_to_DISO9img Bone Diseases C0005940
DISO_to_ANAT8img Petrous Bone C0031266
DISO_to_ANAT8img Temporal Bone C0039484
DISO_to_ANAT8img Tympanic Membrane C0041445
DISO_to_ANAT6img Ear, External C0013453
DISO_to_DISO6img Bone Diseases C0005940
DISO_to_DISO6img Otitis Media C0029882
DISO_to_ANATis_associated_anatomic_site_ofimg Head and neck structure C0460004
DISO_to_DISOmapped_toimg CHOLESTEATOMA, CONGENITAL C0395886
DISO_to_DISOmapped_toimg Cholesteatoma C0008373
DISO_to_DISOmapped_toimg Cholesteatoma &/or aural polyp C0395856
DISO_to_DISOisaimg Cholesteatoma extern ear C0155398
DISO_to_DISOisaimg Cholesteatoma of middle ear / mastoid C0008374
DISO_to_DISOmapped_toimg Cholesteatoma with complications C0395885
DISO_to_DISOisaimg Cholesteatoma, Middle Ear C0155490
DISO_to_DISOmapped_toimg Keratosis - middle ear C0271465
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=812, Pubmed Id: 12684689, UMLKSK CUI: C0008373
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=694, Pubmed Id: 17989584, UMLKSK CUI: C0008373
HumanSLC3A26520solute carrier family 3 (amino acid transporter heavy chain), member 2
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanS100A86279S100 calcium binding protein A8
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanS100A16271S100 calcium binding protein A1
img GENERIF, Score=812, Pubmed Id: 16969478, UMLKSK CUI: C0008373
HumanMAPK35595mitogen-activated protein kinase 3
img GENERIF, Score=1000, Pubmed Id: 15880942, UMLKSK CUI: C0008373
HumanPGF5228placental growth factor
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanIVL3713involucrin
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanICAM23384intercellular adhesion molecule 2
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanHGF3082hepatocyte growth factor (hepapoietin A; scatter factor)
img GENERIF, Score=812, Pubmed Id: 15875782, UMLKSK CUI: C0008373
HumanFGF22247fibroblast growth factor 2 (basic)
img GENERIF, Score=812, Pubmed Id: 15875782, UMLKSK CUI: C0008373
HumanEGF1950epidermal growth factor
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanDEFB4A1673defensin, beta 4A
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanCTSL11514
img GENERIF, Score=1000, Pubmed Id: 11771045, UMLKSK CUI: C0008373
HumanCTSD1509cathepsin D
img GENERIF, Score=1000, Pubmed Id: 12011767, UMLKSK CUI: C0008373
HumanBCL2L1598BCL2-like 1
INFERRED, Score=800, UMLKSK CUI: C0008373
HumanANXA2302annexin A2
INFERRED, Score=800, UMLKSK CUI: C0008373
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0008373Cholesteatoma0self