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Details
Link-It Detail - Disease - Brain Ischemia
Debug Stats
  • ### Total Build Time: 40 ms 43.674 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 326 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 389 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 561 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 1.843 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 2.805 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 13.917 KB
  • CONCEPT_GENES gt=34 ms Completed: 34 ms rowSize= 22.504 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Brain Ischemia C0007786
Definition (1)
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Cerebrovascular Disorders C0007820
Children (4)
img Brain Infarction C0751955
img Ischemic Attack, Transient C0007787
img Vertebrobasilar Insufficiency C0042568
img Hypoxia-Ischemia, Brain C0752308
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Cerebrovascular Disorders C0007820
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Cerebrovascular Disorders C0007820
Relationships (311)

Relation Types:
diso_​to_​anat : 45
diso_​to_​chem : 113
diso_​to_​diso : 111
diso_​to_​gene : 1
diso_​to_​phen : 2
diso_​to_​phys : 39


Relationships:
none : 293
isa : 1
may_​treat : 16
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 13
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO3242img Cerebrovascular accident C0038454
DISO_to_DISO1531img Complication Aspects C1171258
DISO_to_DISO1394img Cerebrovascular accident C0038454
DISO_to_DISO859img Complication Aspects C1171258
DISO_to_CHEM612img Agents, Neuroprotective C0242912
DISO_to_ANAT586img Brain C0006104
DISO_to_ANAT554img Brain C0006104
DISO_to_CHEM494img Agents, Neuroprotective C0242912
DISO_to_PHEN491img genetic aspects C0017399
DISO_to_ANAT476img In Blood C0005768
DISO_to_DISO387img Damage, Reperfusion C0035126
DISO_to_ANAT353img Neurons C0027882
DISO_to_CHEM332img Alteplase C0032143
DISO_to_ANAT327img Neurons C0027882
DISO_to_CHEM316img Fibrinolytic Agents C0016018
DISO_to_PHEN316img genetic aspects C0017399
DISO_to_ANAT286img In Blood C0005768
DISO_to_PHYS282img Cerebrovascular Circulation C0007818
DISO_to_ANAT245img Hippocampus C0019564
DISO_to_DISO240img Damage, Reperfusion C0035126
DISO_to_ANAT203img Hippocampus C0019564
DISO_to_DISO198img Cerebral Infarction C0007785
DISO_to_PHYS191img Cerebrovascular Circulation C0007818
DISO_to_DISO186img CEREBRAL INFARCT MIDDLE CEREBRAL ARTERY C0740392
DISO_to_DISO180img Cerebral Hemorrhage C2937358
Genes (73)

Species:
human : 73
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanEGLN154583egl-9 family hypoxia-inducible factor 1
img GENERIF, Score=1000, Pubmed Id: 17932321, UMLKSK CUI: C0007786
HumanKCNK1054207potassium channel, subfamily K, member 10
img GENERIF, Score=1000, Pubmed Id: 17689202, UMLKSK CUI: C0007786
HumanNDUFA1351079NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
img GENERIF, Score=901, Pubmed Id: 17523870, UMLKSK CUI: C0007786
HumanSMARCAL150485SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanAIFM19131apoptosis-inducing factor, mitochondrion-associated, 1
img GENERIF, Score=1000, Pubmed Id: 18593521, UMLKSK CUI: C0007786
HumanPROZ8858protein Z, vitamin K-dependent plasma glycoprotein
img GAD, Score=1000, Pubmed Id: 14671240, UMLKSK CUI: C0007786
HumanTNFSF128742tumor necrosis factor (ligand) superfamily, member 12
img GENERIF, Score=899, Pubmed Id: 15681834, UMLKSK CUI: C0007786
HumanCYP4F28529cytochrome P450, family 4, subfamily F, polypeptide 2
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanUCP27351uncoupling protein 2 (mitochondrial, proton carrier)
img GENERIF, Score=1000, Pubmed Id: 17052689, UMLKSK CUI: C0007786
HumanTP537157tumor protein p53
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanTLR47099toll-like receptor 4
img GENERIF, Score=1000, Pubmed Id: 15258789, UMLKSK CUI: C0007786
HumanTHBD7056thrombomodulin
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanTBXA2R6915thromboxane A2 receptor
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanTAC16863tachykinin, precursor 1
img GENERIF, Score=734, Pubmed Id: 12578734, UMLKSK CUI: C0007786
HumanROS16098c-ros oncogene 1 , receptor tyrosine kinase
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanRELA5970v-rel avian reticuloendotheliosis viral oncogene homolog A
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanPTGIS5740prostaglandin I2 (prostacyclin) synthase
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanPRNP5621prion protein
img GENERIF, Score=1000, Pubmed Id: 16192387, UMLKSK CUI: C0007786
HumanPRKCH5583protein kinase C, eta
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanPON15444paraoxonase 1
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanSERPINE25270serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanPDE4D5144phosphodiesterase 4D, cAMP-specific
INFERRED, Score=800, UMLKSK CUI: C0007786
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
INFERRED, Score=800, UMLKSK CUI: C0007786
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0007786Brain Ischemia0self