Human | EGLN1 | 54583 | egl-9 family hypoxia-inducible factor 1 | PHD inhibitors preferentially bind to the active site of PHD2 and stabilize HIF activity, induce angiogenesis and protect against cerebral ischemia |
Human | KCNK10 | 54207 | potassium channel, subfamily K, member 10 | Predicts the role of TREK-2 in brain ischemia, memory and other tissues.[REVIEW] |
Human | NDUFA13 | 51079 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | The IFN-beta- and tretinoin-induced GRIM-19 is upregulated during focal cerebral ischemia |
Human | SMARCAL1 | 50485 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | AIFM1 | 9131 | apoptosis-inducing factor, mitochondrion-associated, 1 | Promoting neuronal survival of GDNF might be related to the reduction of AIF nuclear translocation, indicating the high therapeutic potency of SeV/GDNF for cerebral ischemia |
Human | PROZ | 8858 | protein Z, vitamin K-dependent plasma glycoprotein | Title:A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young.|Association:Y|Conclusion:The A allele of an intron F polymorphism of the PZ gene appears to be a novel protective genetic marker for the risk of cerebral ischemia in young adults. In the context of juvenile stroke, high PZ plasma levels may represent a prothrombotic condition. |
Human | TNFSF12 | 8742 | tumor necrosis factor (ligand) superfamily, member 12 | TWEAK may play an important role in ischemia-induced brain injury |
Human | CYP4F2 | 8529 | cytochrome P450, family 4, subfamily F, polypeptide 2 | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | UCP2 | 7351 | uncoupling protein 2 (mitochondrial, proton carrier) | In conclusion, our results provide correlative evidence for the "PPARgamma-->UCP2-->neuroprotection" cascade in ischemic brain injury |
Human | TP53 | 7157 | tumor protein p53 | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | TNF | 7124 | tumor necrosis factor | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | TLR4 | 7099 | toll-like receptor 4 | The Asp299Gly TLR4-allele might have a protective role in carotid atherosclerosis, but not in cerebral ischemia |
Human | THBD | 7056 | thrombomodulin | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | TBXA2R | 6915 | thromboxane A2 receptor | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | TAC1 | 6863 | tachykinin, precursor 1 | The release of substance P is higher during the first 12 hours after a cerebral ischemia attack, decreasing later but remaining high compared to controls |
Human | ROS1 | 6098 | c-ros oncogene 1 , receptor tyrosine kinase | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | RELA | 5970 | v-rel avian reticuloendotheliosis viral oncogene homolog A | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | PTGIS | 5740 | prostaglandin I2 (prostacyclin) synthase | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | PRNP | 5621 | prion protein | study suggests that PrPC has physiological relevance to cerebral ischemic injury and could be useful as a therapeutic target for the treatment of cerebral ischemia |
Human | PRKCH | 5583 | protein kinase C, eta | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | PON1 | 5444 | paraoxonase 1 | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | SERPINE2 | 5270 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | PDE4D | 5144 | phosphodiesterase 4D, cAMP-specific | INFERRED, Score=800, UMLKSK CUI: C0007786 |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | INFERRED, Score=800, UMLKSK CUI: C0007786 |